R-CHOP PROTOCOL FOR DLBCL, NHL

Name: __________________Chart #___________ Age: __yr ,Wt::___kg, Ht::___cm, BSA:___m2

DAY 1 2 3 4 5
RITUXIMAB X
CYCLOPHOSPHAMID X

E
DOXORUBICIN X
VINCRISTINE X
PRIDNISOLONE X X X X X

Premedication

Metoclopramide _______mg slow IV Push over 1-2

minutes q6h (0.5 mg/kg/dose)
Diphenhydramine ______mg PO/IV q4h
(1 mg/kg/dose)
Diphenhydramine 1mg/kg PO 30 – 60 minutes pre-rituximab
Acetaminophen ________PO 30–60 minutes pre-rituximab
Prehydratewith ____________
Rituximab__________mgIV infusion(375 mg/m2) on day 1
Cyclophosphamide________mg in 200 ml NS IV
over 2 hour(750mg/m2) on day 1

Mesna_________

Doxorubicin_________mg in 100ml NS IV over 1hr(50mg/m2) on day 1

Vincristine_____mgIVpush (1.4mg/m2, max 2 mg, 0.05 mg/kg if wt<10 kg) on day 1

Pridnisolone____________ 60mg/m2? Po daily from day1 to day 5