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Why Are Physicians and Laboratories Worried About Biotin
Why Are Physicians and Laboratories Worried About Biotin
Why Are Physicians and Laboratories Worried About Biotin
https://www.corelaboratory.abbott/us/en/offerings/assays/biotin-consumers.html 27/9/2018
Biotin for Consumers | Abbott Core Laboratory Page 2 of 3
Biotin is a key component of the biotin-streptavidin method that is used by many laboratory tests
today. Problems can occurs when these tests are performed on a patient who is taking biotin
supplements. These supplements raise the level of biotin in the patient’s blood which can interfere
with the ability of the test to perform properly.
There are recent published reports of patient misdiagnosis due to biotin interference
• New England Journal of Medicine: August 2016: Biotin Treatment Mimicking Graves’ Disease
• January 2016: Thyroid Month: Beware of Biotin, Endocrine News.
The growing trend of biotin users (in the millions) is making laboratories alert to the increased risk of
test interference. There are also laboratory tests that physicians can request that are not impacted by
biotin.
Inform your doctor if you are taking biotin and alert them that this could interfere with certain blood
tests. Ask your doctor to make sure that the tests ordered are performed on diagnostic products that
are not impacted by biotin.
Skipping your daily biotin supplement before your test does not guarantee that results will be accurate.
Biotin has been known to be in your system for up to several weeks, and can still impact results.
Below is a link to a discussion guide you can take to your physician regarding your biotin usage and
laboratory tests.
https://www.corelaboratory.abbott/us/en/offerings/assays/biotin-consumers.html 27/9/2018
Biotin for Consumers | Abbott Core Laboratory Page 3 of 3
7. Saint Paul LP, Debruyne D, Bernard D, Mock DM and Defer GL. Pharmacokinetics and
pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis,
2016; Expert Opinion on Drug.
https://www.corelaboratory.abbott/us/en/offerings/assays/biotin-consumers.html 27/9/2018