Suspensions

Simple Syrup (BP)

Prepare 250 ml of syrup

Sucrose 66.7%

Water Q.s 100%

Procedure:
1- Add approx. 110 ml water to glass beaker
2- Heat while mixing using magnetic stirrer
3- Add Sucrose gradually while mixing
4- Adjust volume to 250 ml using purified water while mixing until completely dissolved

Sedimentation Volume

Prepare 100 ml of the following Suspension

Zinc oxide 5%

Syrup up to 100%

Procedure

1- Triturate zinc oxide with a small quantity of syrup in a mortar

2- Add slowly small amounts of syrup while triturating
3- Continue until all the syrup is added
4- Transfer to a graduated Cylinder and cover with a para film
5- Leave the suspension for sedimentation

Questions:

1- Calculate the sedimentation volume F

2- How can you increase the stability of this suspension
3- Is this system Flocculated or deflocculated and why
Chloramphenicol suspension

Prepare 100 ml of the following formula

Formula: (prepare 100ml)

Chloramphenicol palmitate 4g
Glycerin 20 g
Xanthan gum 0.2 g
Flavoring agent q.s
Simple syrup 50g
Water up to 100 ml

Procedure
1. Triturate Chloramphenicol palmitate with Glycerin and xanthan gum in a
mortar to give a smooth pourable paste.
2. Dilute the paste with simple syrup , mix.
3. Transfer to a beaker , then add the rest of the syrup and add the flavor.
4. Complete to volume with water.
5. Transfer to a clean bottle and fix a label

Qustions:

1- Describe the purpose of each ingredient

2- How can modify the system flocculation

Ranitidine suspension

Prepare 50 ml of suspensions containing 1%(W/V) ranitidine hydrochloride from available

tablet which contains 150 mg ranitidine hydrochloride per tablet . The suspension also contains
50%(V/V) sugar syrup, 0.9% (W/V) Xanthan gum and Purified water .

Ingredient Percentage Quantity

ranitidine hydrochloride
Xanthan gum
sugar syrup
Purified water
Calculation:
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METHOD OF PREPERATION:
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