Name of Drug Classification Mechanism of Action Contraindication Indication Adverse Effects Nursing

Responsibilities
Generic Antiasthmatic and Aminophylline is a Acute porphyria, relief of Nausea, vomiting,  Administer
Name: COPD preparation methylxanthine bronchodil concomitant use bronchospasm headache, to pregnant
Aminophylline ator composed with other associated hypokalaemia, patients
of theophylline (Respbid,  xanthine with asthma hypophosphatae only when
Brand Slo-Bid, Theo-24, Theolai derivatives and in chronic mia, clearly
name/s: r) and ethylenediamine. obstructive hypernatraemia, needed—
Norphyl, The mechanism of action pulmonary hyperglycemia, neonatal
Phyllocontin, of aminophylline is not disease acid/base tachycardia,
Truphylline. completely understood. disturbance, jitteriness,
Dosage: Theophylline relaxes anxiety, insomnia, and
PO Chronic smooth muscle in the maniacal withdrawal
bronchospasm respiratory tract and behavior, apnea
(tablet) initial: suppresses airway stimuli. delirium, observed
225-450mg bid Theophylline also confusion, when
IV Acute increases contraction restlessness, mothers
severe of diaphragm muscles by irritability, received
bronchospasm increasing calcium uptake hyperventilation, xanthines
loading: through chemical dizziness, tremor, up until
5mg/kg or channels. convulsions delivery.
250-500mg by  Caution
slow inj or patient not
infusion to chew or
Maintenance: crush
0.5mg/kg/hr enteric-
Maximum: coated
25mg/min timed-
Route: release
Intravenous forms.
Oral  Do not give
timed-
release
forms with
food; these
should be
given on an
empty
stomach 1
hr before or
2 hr after
meals.
 Maintain
adequate
hydration.
 Monitor
results of
serum
theophylline
levels
carefully,
and arrange
for reduced
dosage if
serum
levels
exceed
therapeutic
range of
10–20
mcg/mL.
 Take serum
samples to
determine
peak
theophylline
concentrati
on drawn
15–30 min
after an IV
loading
dose.
 Monitor for
clinical
signs of
adverse
effects,
particularly
if serum
theophylline
levels are
not
available.
 Ensure that
 diazepam is
readily
available to
treat
seizures.
Generic Cephalosporin - Bactericidal: inhibits Contraindicated Cefuroxime is headache,  Check the
Name: Antibiotic given to
synthesis of bacterial cell with allergy to dizziness, doctor’s
Cefuroxime postpartum
wall, causing cell death cephalosporins or mothers to lethargy, order
prevent them
penicillin paresthesia,  Assess for
Brand from post-
name/s: operational nausea, vomiting, history:
Ceftin infections
diarrhea, hepatic and
especially c/s
Dosage: mothers. anorexia, renal
750mg every
abdominal pain, impairment,
8hrs,
flatulence, lactation,
depending on
nephrotoxicity, pregnancy
the severity
bone marrow  Assess for
depression physical
Route:
Tablets: (decreased WBC, cues: skin
125,250,500m platelets, Hct), status,
g Hypersensitivity LFTs, renal
Suspension:12 ranging from rash function
5mg/5ml, to fever to tests,
250mg/5ml anaphylaxis; culture of
serum sickness affected
reaction area

 Have Vit. K
available in
case
hypoprothro
 mbinemia
occurs
 Culture
injection
site, and
arrange for
sensitivity
tests before
and during
therapy if
expected
response is
not seen
take the
patients BP

During
 Administer
the right
drug

 Explain to
the patient
about the
importance
and
purpose of
the drug
  Administer
at the right
time and
right
dosage
 Avoid
alcohol
while taking
this drug
and for 3
days after
because
severe
reactions
often occur
 Discontinue
if
hypersensiti
vity reaction
occurs

After:

 Document
and record.
 Take note
of side
effects:
 stomach
upset or
diarrhea
 Report
severe
diarrhea,
difficulty
breathing
and
unusual
tiredness or
fatigue,
pain at
injection
site
 Take
patient’s
Vital Signs
 Perform
bedside
care
Generic Mucolytic It enhances pulmonary There are no Productive Gastrointestinal  Monitor for
Name: surfactant production and absolute cough disturbances, S&S of
Ambroxol stimulates ciliary activity. contraindications allergic reaction aspiration
These actions result in but in patients of excess
Brand improved mucus flow and with gastric secretions
name/s: transport (mucociliary ulceration relative and for
Mucosolvan clearance). Enhancement caution should be bronchospa
of fluid secretion and observed. sm
Dosage: mucociliary clearance (unpredicta
Adults: daily facilitates expectoration ble);
dose of 30 mg and eases cough. withhold
(one Ambroxol drug and
tablet ) to 120 notify
mg (4 hysician
Ambroxol immediately
tablets) taken if either
in 2 to 3 occur.
divided doses  Lab test:
Monitor
Children up to ABGs,
2 years: half a pulmonary
teaspoonful functions
Ambroxol and pulse
syrup twice oximetry as
daily indicated.
 Have
Children 2 - 5 suction
years: half a apparatus
teaspoonful immediately
Ambroxol available.
syrup 3 times Increased
daily volume of
respiratory
Children over tract fluid
5 years: One may be
teaspoonful liberated;
Ambroxol suction or
syrup 2-3 endotrache
times daily. al aspiration
may be
Route: necessary
Oral to establish
and
maintain an
open
airway.
Patient Education
 Report
difficulty
with
clearing the
airway or
 any other
respiratory
distress.
Generic Beta-Blockers History of  tremors, angin Cold extremities,  WARNING:
Name: Antimigraine bronchial asthma, a (chest insomnia, fatigue, Do not
Propanolol preparation The way that this drug bronchospasm pain), hyperten dizziness, vivid discontinue
chronic sion (high bloo dreams, drug abruptly
works to lower blood
Brand obstructive d pressure), lassitude, after long-term
name/s: pressure is not clearly airways disease, heart rhythm nausea, therapy
Hemangeol, bradycardia, disorders, and constipation or (hypersensitivi
Inderal LA, understood. It reduces the cardiogenic other heart or diarrhoea, ty to
Inderal XL, workload of the heart and shock, circulatory vomiting, catecholamine
InnoPran XL, hypotension, conditions, anorexia, s may have
Inderal blocks the release of a metabolic heart attack, stomach developed,
substance called renin acidosis, severe and to reduce discomfort, causing
Dosage: peripheral arterial the severity impotence. exacerbation
Oral: from the kidneys. circulatory and frequency Weakness, of angina, MI,
20mg/5ml – disturbances, 2nd of migraine paraesthesia, and ventricular
40mg/5ml or 3rd degree headaches. wheezing, arrhythmias).
IV: 1mg/ml The beta-blocking heart block, sick pharyngitis, Taper drug
properties help to control sinus syndrome, bronchospasm. gradually over
Route: untreated CNS 2 wk with
Oral heart rhythm, delay the pheochromocyto disturbances at monitoring.
Intravenous ma, uncontrolled higher doses and  WARNING:
start of chest pain, prevent
heart failure, mood alterations. Ensure that
migraines, and Prinzmetal’s Thrombocytopeni alpha-
angina. c purpura, adrenergic
reduce tremors. It isn’t
agranulocytosis, blocker has
fully understood how this nonthrombocytop been given
enic purpura, before giving
drug works to treat these thrombocytopenia propranolol
problems. . Depression, when treating
confusion, patients with
cognitive pheochromocy
dysfunction, toma;
emotional lability, endogenous
fatigue, catecholamine
hallucinations. s secreted by
Potentially the tumor can
Fatal: Heart cause severe
failure, heart hypertension if
block and vascular beta
bronchospasm. receptors are
blocked
without
concomitant
alpha
blockade.
 Consult
with physician
about
withdrawing
drug if patient
is to undergo
surgery
(withdrawal is
controversial).
 Provide
continuous
cardiac and
regular BP
monitoring
with IV form.
Change to oral
form as soon
as possible.
 Give oral
drug with food
to facilitate
absorption.