Social listening report

PATIENT RECRUITMENT
AND RETENTION
August—September 2020
SEARCHES
Two key searches were carried out, enabling us to see the differences between COVID-19 being
included or excluded on the number of mentions about ‘Patient recruitment’ and ‘Patient retention’.
The timeframe for the research was the last 30 days, which was 23rd August—22nd September 2020
at the time of writing.

Total Mentions Mentions/Day Average

Excluding COVID-19 mentions

(”patient recruitment” OR “patient retention”)
NOT (“coronavirus” OR “COVID-19” OR “COVID 19” OR “corona”)
3.04k 105
+ 52% + 52%

Including COVID-19 mentions

(”patient recruitment” OR “patient retention”)
AND (“coronavirus” OR “COVID-19” OR “COVID 19” OR “corona”)
5.37k 185
+ 16% + 16%
ACTIVITY RESULTS EXCLUDING COVID-19

+ The mentions of ‘Patient recruitment’ and ‘Patient retention’

throughout the past 30 days have shown lots of peaks throughout
the month. The spikes in mentions on certain days may be due to
certain news articles that have been published and shared across
multiple platforms, by different people and businesses.

+ The biggest spike was on 17th September 2020. On this day,

there were 335 news mentions and 21 twitter mentions.

+ The popular news articles and tweets that mentioned patient

recruitment and retention on this day include:
- The Value of Clinical Trial Referral Platforms
- Patient recruitment starts for the international PRO-SID study
evaluating Panzyga® for primary prophylaxis in patients with chronic
lymphocytic leukaemia and secondary immunodeficiency
- HealthLynked Scores An Integration Agreement With athenahealth;
Set’s The Stage For More Exchange

+ Developments of new drugs for specific diseases

+
Online mentions
covered: +
Site development
New recruitment plans
+ One of COUCH Health’s own blogs contributed to this spike,
+ Development of new technologies for patients with a widespread reach of 1.8k views:
- How to lessen site burden with a targeted patient recruitment strategy
ACTIVITY RESULTS INCLUDING COVID-19

+ Similar to the first search, the search results including

COVID-19 showed a high degree of variability throughout the
30-day timeframe.

+ The biggest spike of activity was on 8th September 2020.

On this day, there were 647 news mentions, 99 blog mentions
and 1 Facebook mention.

+ Though not directly related to patient recruitment, the Ascendis

Pharma news regarding their EMA application was a highlight over
the past 30 days. The news article was mentioned in the majority
of posts, as they are seeking approval on an investigational
long-term growth hormone treatment not currently approved yet.

+ Other topics that were mentioned a great deal online included:

- North American Healthcare CRO Services Market 2020-2027: $40 Billion
Opportunity Assessment

Online mentions
- Pfizer’s Call for Clinical Trial Diversity: But How do We Get There?
covered usually + The effect of COVID-19 - MAGI’s clinical research conference
included more + Developments in medicines/drugs
mentions about how + Increase in clinical trials due to COVID-19 - Carlyle Makes Strategic Growth Investment in TriNetX; Acquires Majority
COVID-19 has + Market growth Stake in Leading Global Health Research Network
affected the industry:
- 5 Vital Tactics to Improve Patient Recruitment in Clinical Trials
 TOP KEYWORDS
Keyword/Phrase Occurences Keyword/Phrase Occurences

INCLUDING COVID-19 MENTIONS

EXCLUDING COVID-19 MENTIONS

patients 1239 patients 2294

company 838 covid 1940
patient recruitment 560 statements 1575
statements 554 company 1421
contract research organizations 442 development 1371
drug 423 treatment 1200
data 370 clinical trials 1151
efficacy and safety 364 Both have ‘Patient recruitment’ patient recruitment 968
information 361 as a high-ranking keyword. This data 902
report 360 could be due to new clinical clinical studies 686
clinical trials 347 market 678
study 345
trials needing patients and the transcon hgh 664
different stages 307 emphasis on COVID-19 trials ascendis’ prospectus supplement 604
contract development and manufacturing organizations 307 needing patients. ascendis’ product pipeline and expansion 598
formulation development 307 u.s. food and drug administration 585
development activity 306 patients, science and passion 545
u.s. and companies 304
Both have ‘Development’ as a transcon pth and transcon cnp 545
specific activities 304 keyword, which may be due to unmet patient needs 518
different outsourcing needs 304 the advancements that the ascendis’ ability 513
services and technologies 302 industry is making with drugs actual results 508
technologies 288 results 503
treatment 286
and patient technologies. companies 426
manufacturing needs 284 proprietary transcon platform 423
medical device development 281 ascendis pharma 418
current patient information 280 study 408
technologies, trends, products and market participants 279 unmodified parent drug 403
access 278 study drug 402
cll patients 274 market potential 392
chronic lymphocytic leukaemia 274 north america 376
 TOP LOCATIONS
Locations Count Locations Count

INCLUDING COVID-19 MENTIONS

EXCLUDING COVID-19 MENTIONS

United States 1891 United States 4407

Patient recruitment and retention

United Kingdom 172 Canada 196
is mentioned the most in the
United States, followed by
Canada 171 Canada and the UK. United Kingdom 137

South Korea 147 This might be because these Germany 78

countries are making the most
developments in patient
India 69 India 55
recruitment and retention, as they
are highly developed countries.
Germany 37 For example, new technologies Switzerland 33
available for patients or more
Switzerland 31 drugs being developed, which Australia 20
means more patients are
needed for participation.
Malaysia 22 Austria 17

US news and discussions also

Singapore 22 tend to have a global reach. France 15

Australia 13 Hong Kong SAR China 15

 TOP HASHTAGS The top hashtag for both searches
was #Covid19, despite COVID-19
Keyword/Phrase Count
being excluded from the first search. Keyword/Phrase Occurences

INCLUDING COVID-19 MENTIONS

EXCLUDING COVID-19 MENTIONS

Covid19 109 Covid19 121

Bradford 70 Both searches have ’Bradford’ as a TechNews-PR Newswire 84
Clinicaltrials 30 Bradford 70
high-ranking hashtag. This might be
Healthcare 25 News 26
Clinicaltrial 22
due to the launch of a website Stock Market News 17
Patient 18 developed by Bradford University, Nasdaq:ASND 16
Cancer 17 allowing patients to sign up for US04351P1012 14
Medicalbilling 16 Clinicaltrial 10
COVID-19 vaccine trials.
Pain 16 Coronavirus 9
Patientengagement 16 Business 8
Cannabinoid 15 Many hashtags are news companies Researchmatters 7
Healthcareit 15 and health organisations. For GlobeNewsWire 7
Digitalhealth 15 GlobeNewswire – Stock Market News 7
example, PRNewswire, Ehealth,
Healthit 15 PR Newswire – Stock Market News 5
Patientrecruitment 14
GlobeNewsWire, NewsEdge – which PRNewsWire 5
Qixleef 14 may be because they are reliable Science 5
Medtwitter 13 places to receive information. World 4
Doctors 13 Covid19vaccine 4
Simplifyingselection 13 North 4
Emrfinder 13
The search which included COVID-19 Stocks 4
Publichealth 13 mentions had more hashtags related Benzinga 3
Whywedoresearch 11 to places to find information about Benzinga – Stock Market News 3
Pharma 9 BusinessWire – Stock Market News 3
patient recruitment and retention,
Research 9 BusinessWire 3
Nhs 9
such as news companies and health Global 3
Watchthisspace 9 organisations. Whereas, the search Rare Diseases 3
Business & professional service press release 8 excluding COVID-19 mentions had NewsEdge 3
Ehealth 8 USA 3
more hashtags relating to patient
Health 8 Clinicalresearch 3
recruitment and retention. For
example, patient engagement,
doctors, clinical trials, and patient.
 EMOTIONAL AND SENTIMENT COMPARISON
Category Count Category Count

INCLUDING COVID-19 MENTIONS

EXCLUDING COVID-19 MENTIONS

Joy 522 Joy 1264

Fear 26 In the emotional analysis of Fear 103

online mentions, joy was reported
the highest across both searches.
Surprise 4 Surprise 10
This may be because of potential
breakthroughs and progress
Anger 2 within clinical trials in general. Anger 0

Love 30 However, fear and negative Love 17

sentiments can also be seen
Sadness 7
across all posts too, which is Sadness 6
understandable with the
devastating impact of COVID-19.
Not Rated 7 Not rated 5

The overall sentiment for both

Negative 39 was Neutral, suggesting mixed Negative 33
views and both positive and
Positive 181 negative terminology used. Positive 532

Neutral 2814 Neutral 4799

TWITTER INSIGHTS EXCLUDING COVID-19
KEY METRICS FOR TWITTER TWEET TYPE BREAKDOWN

259 331 1.33m

Users Mentions Impressions

TOP EMOJIS
MOST RETWEETED
TWITTER INSIGHTS INCLUDING COVID-19
KEY METRICS FOR TWITTER TWEET TYPE BREAKDOWN

157 176 429k

Users Mentions Impressions

TOP EMOJIS
MOST RETWEETED
SUMMARY

Overall, our research has shown that there was a greater number of mentions about ‘Patient
recruitment’ and ‘Patient retention’ when COVID-19 was included in the search during the timeframe.
This could be due to the current climate of clinical trials and finding a vaccine for COVID-19.

The online mentions covered recent developments in drugs, treatments for specific diseases,
and an emphasis on market growth in certain blogs and news articles.

The overall emotion expressed in the online mentions was joy. This could be due to recent
developments the industry has made. However, there are still feelings of fear displayed online
and the overall sentiment was neutral. This suggests that there are still worries and concerns
around the topic of ‘Patient recruitment’ and ‘Patient retention’.

There was a lack of mentions of ‘Patient retention’ in the results. This could suggest there is more
focus on patient recruitment within the industry, and patient retention is overlooked.
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All report information is correct as of October 2020. Unless COUCH Health provide prior written consent, no part of this report should be reproduced, distributed or communicated
to any third party. COUCH Health do not accept any liability if this report is used for an alternative purpose from which it is intended, nor to any third party in respect of this report.