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  • Captopriloxidation Int JPharm

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    This study investigated factors that affect the stability of the drug captopril in aqueous solution, including pH, temperature, and the presence of common excipients. The drug was found to be most stable at pH 5-6 and degraded more quickly at higher temperatures. Several excipients like HPMC helped to improve the chemical stability of captopril in solution.

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    CaptopriloxidationIntJPharm

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    This study investigated factors that affect the stability of the drug captopril in aqueous solution, including pH, temperature, and the presence of common excipients. The drug was found to be most stable at pH 5-6 and degraded more quickly at higher temperatures. Several excipients like HPMC helped to improve the chemical stability of captopril in solution.

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    © All Rights Reserved
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    13 views9 pages

    Captopriloxidation Int JPharm

    Uploaded by

    armiatin
    This study investigated factors that affect the stability of the drug captopril in aqueous solution, including pH, temperature, and the presence of common excipients. The drug was found to be most stable at pH 5-6 and degraded more quickly at higher temperatures. Several excipients like HPMC helped to improve the chemical stability of captopril in solution.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    See discussions, stats, and author profiles for this publication at: https://www.researchgate.

    net/publication/256595621

    Factors affecting captopril stability in aqueous solution

    Article  in  International Journal of Pharmaceutics · August 1982


    DOI: 10.1016/0378-5173(82)90083-7

    CITATIONS READS

    41 676

    3 authors, including:

    Peter Timmins Y. John Wang


    Bristol-Myers Squibb Genentech
    151 PUBLICATIONS   3,033 CITATIONS    72 PUBLICATIONS   2,165 CITATIONS   

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    Some of the authors of this publication are also working on these related projects:

    HPMC Research View project

    Currently developing projects for polymer-based oral drug delivery in the area of drug-polymer-water interactions View project

    All content following this page was uploaded by Y. John Wang on 11 January 2018.

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