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Uric Acid, Blood (PubMed
Overview
Indications Cross Links
Interfering Factors
agent
Potential Medical Davis's Lab & Diagnostic Tests " # $ % & '
Diagnosis: Clinical Calculi, Renal
Significance of
Results Uric Acid, Blood calculus
Nursing
Implications Synonym/Acronym: gout
Before the Study: Urate. Hypertension
Planning and
Implementation Rationale hyperuricemia
After the Study: To monitor uric acid levels during treatment for gout and evaluation of tissue
Potential Nursing destruction, liver damage, renal function, and monitor the effectiveness of Hyponatremia
Actions therapeutic interventions.
kidney
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical Leukemia,
direction. Acute

Normal Findings niacin

Method: Spectrophotometry.
Normal
Reference
Age Conventional SI Units (Conventional Units × Laboratory
Units 0.059) Values
1–30 days
Polycystic
Male 1.3–4.9 mg/dL 0.08–0.29 mmol/L Kidney
Disease
Female 1.4–6.2 mg/dL 0.08–0.37 mmol/L

1–3 mo Polycythemia

Male 1.4–5.3 mg/dL 0.08–0.31 mmol/L Preeclampsia

Female 1.4–5.8 mg/dL 0.08–0.34 mmol/L substance

4–12 mo urine
Male 1.5–6.4 mg/dL 0.09–0.38 mmol/L

Female 1.4–6.2 mg/dL 0.08–0.37 mmol/L

1–3 yr Related Topics

Male and female 1.8–5 mg/dL 0.11–0.3 mmol/L hyperuricemia

4–6 yr Uric Acid,

Urine
Male and female 2.2–4.7 mg/dL 0.13–0.28 mmol/L

7–9 yr substance

Male and female 2–5 mg/dL 0.12–0.3 mmol/L rasburicase

10–12 yr agent
Male and female 2.3–5.9 mg/dL 0.14–0.35 mmol/L
sodium citrate
13–15 yr and citric acid

Male 3.1–7 mg/dL 0.18–0.41 mmol/L sulfinpyrazone

Female 2.3–6.4 mg/dL 0.14–0.38 mmol/L
black tea
16–18 yr
probenecid
Male 2.1–7.6 mg/dL 0.12–0.45 mmol/L
more...
Female 2.4–6.6 mg/dL 0.14–0.39 mmol/L

19 yr–Adult

Male 4–8 mg/dL 0.24—0.47 mmol/L

Female 2.5–7 mg/dL 0.15–0.41 mmol/L

Adult older than 60

yr

Male 4.2–8.2 mg/dL 0.25–0.48 mmol/L

Female 3.5–7.3 mg/dL 0.21–0.43 mmol/L

Therapeutic target for patients with gout: Less than 6 mg/dL (SI: Less than 0.4
mmol/L).

Critical Findings and Potential Interventions

Adults

Greater than 13 mg/dL (SI: Greater than 0.8 mmol/L)

Children

Greater than 12 mg/dL (SI: Greater than 0.7 mmol/L)

Timely notification to the requesting health-care provider (HCP) of any critical

findings and related symptoms is a role expectation of the professional nurse. A
listing of these findings varies among facilities.

Symptoms of acute renal dysfunction and/or chronic kidney disease associated

with hyperuricemia include altered mental status, nausea and vomiting, fluid
overload, pericarditis, and seizures. Prophylactic measures against the
development of hyperuricemia should be undertaken before initiation of
chemotherapy. Possible interventions include discontinuing medications that
increase serum urate levels or produce acidic urine (e.g., thiazides and
salicylates); administration of fluids with sodium bicarbonate as an additive to IV
solutions to promote hydration and alkalinization of the urine to a pH greater than
7; administration of allopurinol 1 to 2 days before chemotherapy; monitoring of
serum electrolyte, uric acid, phosphorus, calcium, and creatinine levels; and
monitoring for ureteral obstruction by urate calculi using computed tomography or
ultrasound studies. Possible interventions for advanced renal insufficiency and
subsequent chronic kidney disease may include peritoneal dialysis or
hemodialysis.

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