DR.

OLIGO
192c
High Throughput Oligo Synthesizer

Full Service Plan

Covers all parts, labor and travel required to
maintain your instrument to factory functional
specifications.

Low Use Service Plan

Covers parts, labor and travel but is limited in
the number of service visits, labor hours and
parts.

Pay As You Go Service Plan

Pay for service travel, labor and parts as you
need them.

TM
 INTRODUCING THE DR. OLIGO 192C
Biolytic Lab Performance, Inc. is proud to introduce the Dr. Oligo 192c – our latest high throughput oligo
synthesizer. Now restructured with all the same principles that helped us become the industry's gold standard, the
192c is a faster, more compact model that can adapt to fit the various needs of our customers. This instrument
came to life through innovative ideas of quality improvement, upgraded features and cost-efficiency - all of which
have allowed us to provide Biolytic’s proven reliability at a much more affordable price. The Dr. Oligo 192c is truly an
advancement in high throughput oligo synthesis.
Customers all over the world use nucleic acids produced by our Dr. Oligo synthesizers for their own unique
purposes. From applications like oligonucleotide and gene synthesis, genetic test kits, PCR/RT-PCR, siRNA/RNAi,
miRNA, CRISPR Cas9, and DNA/RNA sequencing - to broader areas like evolutionary history, forensics, immuno-
therapy, diagnostic and therapeutic research – to high-throughput screening, natural product biosynthesis, reverse
transcription PCP, hybridization, and SNPS – the variety is tremendous. Recently some have even endeavored into
using nucleic acids as computer information storage devices, storing animated videos in DNA. The Dr. Oligo line
has evolved alongside these cutting-edge discoveries, and with the 192c it will continue to play a significant role in
modern science.

FEATURES
Reduced Footprint
The Dr. Oligo 192c has been reduced in volume by more than 40% from the original 192,* taking up just a fraction of the
space in your lab.

Secure Bottle Containment System

A new bottle containment system protects the
instrument and its users against spills and
breakage. Your bottles are safely isolated
behind a transparent door, and in the event of
breakage, our innovative sealed catch tray
drains directly to waste.

Flexibility
Our Dr. Oligo 192c base model is compatible with up to 10 reagents - 4
standard and up to 6 additional reagents of any combination of the
following: specials, second oxidation, double deblock or double wash. The
open-frame structure of this instrument provides many opportunities for
customization, supporting increased reagent counts and throughput.

Maintainability
Maintenance is made simpler. Purge, drain and pneumatic plumbing is
physically separate from the bottle system, enabling easy and individual
access. This industry-leading design creates unparalleled efficiency and
serviceability.

Certified Training
As with all of our instruments, Biolytic Certified Training (CIT) is available for
the Dr. Oligo 192c. Upon successful completion of the certificate program,
recipients will be able to understand the function of the instrument, how to
operate it, and how to perform basic troubleshooting.

This training, coupled with the 192c’s simple maintenance, will decrease
total operation costs for the 192c. Please contact our sales department for
more information and restrictions on this optional program.

*Excludes slider plate

www.biolytic.com sales@biolytic.com (510) 795-1142

 FEATURES
CONTINUED
Biolytic Boards
The debut of the Dr. Oligo 192c is also the introduction of Antistatic & Shockproof
our new Driverless Biolytic Control Boards. The control Ensures the control boards are not
boards consist of 32 outputs and 8 inputs, designed by affected by static electricity that can
Biolytic specifically for our Dr. Oligo synthesizer line. They build up and disrupt delivery, and
ensure proper dispensing of as little as 2ul* and are controls instrument movement to
make sure reagents are not affected
complete with an antistatic, shockproof design, on-board during synthesis.
timing, valve short protection, valve flood protection, and
real-time monitoring of valve electrical integrity. On-Board Timing
Guarantees reliability by executing the exact timing required by
delivery.

Valve Short Protection

If a valve shorts electrically, the board shuts down that driver
and protects itself, thus eliminating the need to replace a board.

Valve Flood Protection

This ensures that valves will shut down and synthesis will
pause if communication is lost between the PC and boards.

Real-time Valve Monitoring

Just prior to and during synthesis, the control boards monitor
Improved Software electrical integrity of all instrument valves. If any valve is in poor
condition, the run will immediately pause and allow an operator
The 192c software has faster loading times, updated user to resolve the issue
interface, advanced security, and a new Hardware Monitoring
System.

Security and Encryption

Increased Efficiency
Our original 192 model came with a manual
The software offers encrypted communication, which increases
washing system and an additional automated
system uptime and improves the overall quality of each
wash option. The 192c redefines that standard
synthesis.
by including nozzle washing with every
Hardware Monitoring System instrument. The reagent delivery system is now
This new feature keeps operators updated on the status of made with smaller valves and fills with less
instrument hardware, including the Biolytic Boards and motor. volume, thus cutting down unnecessary costs
The system works in conjunction with our control boards to by reducing waste and allowing for faster,
prompt users to take action in the event of hardware failure. more consistent response times.

Ease of Use
Side-by-side Slider Plate Windows
The Dr. Oligo 192c nozzle plate windows are now located side-by-side, a
reconfiguration that allows users to oversee both reaction plates at the
same time.
LED Bottle Backlighting
We have also added chemically safe LED backlighting to the bottle
compartment, which makes monitoring reagent levels more convenient and
ensures that the instrument is always prepared for synthesis.

The Gold Standard

Backed by Biolytic Lab Performance, Inc.’s 25 years of experience in reliable and
efficient Oligo Synthesizers, these instruments are strategically constructed to optimize
high quality and cost-efficiency, making the Dr. Oligo 192c exceptional and affordable.

*Actual minimal controlled dispense volume is dependent on use of the Biolytic Board V1 and appropriate reagent delivery system

www.biolytic.com sales@biolytic.com (510) 795-1142

 DR. OLIGO
192c
High Throughput Oligo Synthesizer

BASE MODEL
SPECIFICATIONS

Oligos synthesized in one run 192

Synthesis Scales 1nMole to 2uMole

Flow Control Positive Pressure

Synthesis Capabilities DNA, RNA, 2’ Omethyl, LNA

Amidite Delivery Systems Up to 10 (4 standard and 6 special)

Special Amidite Delivery Systems Up to 6

Dispense Nozzles per Reagent 8 or 16

*Wash and Deblock*

Gas Inputs 1) Bottle Blanketing 2) Purge/Drain & Pneumatics

Power 100-240VAC, 50-60Hz, 1,000 VA

Size 56.7 x 17.4 x 28.8

Pneumatics Requires 90-120 PSI

User Control Computer with latest Windows Operating System

5680 STEWART AVE.

FREMONT, CA 94538

TM www.biolytic.com
sales@biolytic.com
(510) 795-1142