DRUG STUDY

Patient: B.V Diagnosis: Invasive Ductal Carcinoma

Age: 58y/o Date: October 8, 2020

Name of Drug Mechanism of Action Indication Contraindication Side Effects Nursing Intervention

Generic Name:
CYCLOPHOSPHAMIDE
Brand Name:Cytoxan
Dosage:
PO: 1-5 mg/kg over 2-5
IV: 40-50 mg/kg in
divided doses
PO/IV: 1-5 mg/kg in divided
doses or 50-150 mg/m2
Route:
IV,IO
Inhibition of protein synthesis
through interference with
DNA
replication by alkylation of
DNA
Its most important areas of use  Hypersensitivity, Vomiting • Encourage patient to
are non-Hodgkin's diarrhea drink 2000 – 3000
lymphomas, multiple  Severe bone marrow mL/day to promote
myelomas, chronic lymphatic depression. Caution: weight loss excretion of uric
leukemia, breast cancer, hematuria acid.
small-cell lung cancer,  Pregnancy,
alopecia
neuroblastomas, and several  Liver or kidney • Alkalinization of the
sarcomas. impotence
disease urine may be used to
sterility help prevent uric
acid nephropathy.
ovarian fibrosis
headache
• Assess cardiac and
dizziness respiratory status for
dermatitis dyspnea,
rales/crackles,
cough, weight gain,
edema.

Frequency:

maintenance therapy is 1–5

mg/kg daily

Classification:

Alkylating agents