A. Are The Result of The Trial Valid?

1. Did the trial address a clearly focused issue?

2. Was the assignment of patients to treatments randomized?
3. Were all of the patients who entered the trial properly
accounted for at its conclusion?
4. Were patients, health workers and study personnel “blind” to
treatmenat?
5. Were the groups similar at the start of the trial?
6. Aside from the experimental intervention, were the groups
treated equally?

B. What are The Result?

7. How large was the treatment effect?
8. How precise was the estimate of the treatment effect?

C. Will the Result Help Locally?

9. Can the result be applied to the local population?
10. Were all clinically important outcomes considered?
11. Are the benefits worth the harm and costs?
A. Apakah Hasil Uji Coba Valid?
 
1. Apakah persidangan membahas masalah yang terfokus dengan
jelas?
2. Apakah penugasan pasien untuk perawatan diacak?
3. Apakah semua pasien yang memasuki percobaan
diperhitungkan dengan benar pada kesimpulannya?
4. Apakah pasien, petugas kesehatan dan petugas studi “buta”
terhadap menu pengobatan?
5. Apakah kelompok tersebut serupa pada awal percobaan?
6. Selain dari intervensi eksperimental, apakah kelompok
diperlakukan sama?
 
B. Apa Hasilnya?
7. Seberapa besar efek pengobatannya?
8. Seberapa tepat perkiraan efek pengobatan?
 
C. Akankah Hasilnya Membantu Secara Lokal?
9. Bisakah hasilnya diterapkan pada populasi lokal?
10. Apakah semua hasil penting secara klinis dipertimbangkan?
11. Apakah manfaatnya sepadan dengan kerugian dan biayanya?