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  • Graziella Beatriz A. Cabuyadao Activity 8.1

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    Beverly Cabuyadao
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    The document discusses the mechanisms of action of antibiotics. It lists 5 targets of antibiotics: the bacterial cell wall, cell membrane, protein synthesis, DNA replication and transcription, and folic acid synthesis. It provides examples of common antibiotics that target each mechanism, such as beta-lactams targeting the cell wall and tetracyclines inhibiting protein synthesis. The document also notes some antibiotics used to treat cancer affect mammalian cell mechanisms.

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    ACT8.1-cabuyadao

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    The document discusses the mechanisms of action of antibiotics. It lists 5 targets of antibiotics: the bacterial cell wall, cell membrane, protein synthesis, DNA replication and transcription, and folic acid synthesis. It provides examples of common antibiotics that target each mechanism, such as beta-lactams targeting the cell wall and tetracyclines inhibiting protein synthesis. The document also notes some antibiotics used to treat cancer affect mammalian cell mechanisms.

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    © All Rights Reserved
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    5 views2 pages

    Graziella Beatriz A. Cabuyadao Activity 8.1

    Uploaded by

    Beverly Cabuyadao
    The document discusses the mechanisms of action of antibiotics. It lists 5 targets of antibiotics: the bacterial cell wall, cell membrane, protein synthesis, DNA replication and transcription, and folic acid synthesis. It provides examples of common antibiotics that target each mechanism, such as beta-lactams targeting the cell wall and tetracyclines inhibiting protein synthesis. The document also notes some antibiotics used to treat cancer affect mammalian cell mechanisms.

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    GRAZIELLA BEATRIZ A.

    CABUYADAO

    GRAZIELLA BEATRIZ A. CABUYADAO

    ACTIVITY 8.1

    Transcription 4 Protein synthesis

    Folic acid synthesis

    DNA replication Cell wall


    Cell membrane

    Mechanism of Action Examples of Antibiotics


    1. Cell wall β-lactams, bacitracin, vancomycin
    2. Cell membrane polymyxins
    GRAZIELLA BEATRIZ A. CABUYADAO

    3. Protein synthesis tetracyclines, aminoglycosides, macrolides


    4. >DNA replication DNA synthesis: quinolones inhibit bacterial topoisomerase II
    >Transcription RNA synthesis: rifampin inhibits bacterial RNA polymerase

    Antibiotics that affect mammalian cells:


    irinotecan, etoposide, doxorubicin, actinomycin D- for cancer treatment
    5. Folic acid synthesis sulfonamides trimethoprim

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