Flouoroquinolones:

A quinolone antibiotic is a member of a large group of broad-spectrum

bacteriocidals that share a bicyclic core structure related to the
substance 4-quinolone. They are used in human and veterinary
medicine to treat bacterial infections. They are commonly used to treat a
variety of illnesses such as respiratory and urinary tract infections. These
medicines include ciprofloxacin (Cipro), gemifloxacin (Factive),
levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and
ofloxacin (Floxin).

Ciprofloxacin:
Ciprofloxacin is an antibiotic used to treat several bacterial infections.
This includes bone and joint infections, intra abdominal infections,
certain type of infectious diarrhea, respiratory tract infections, skin
infections, typhoid fever, and urinary tract infections, among others.
SIDE EFFECTS.
  rash
 hives
 itching
 tingling
 swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or
lower legs
 difficulty breathing or swallowing
 hoarseness

CONTRAINDICATIONS:
 diarrhea from an infection with Clostridium difficile bacteria.
 diabetes.
 low blood sugar.
 glucose-6-phosphate dehydrogenase (G6PD) deficiency.
 low amount of magnesium in the blood.
 low amount of potassium in the blood.
 a low seizure threshold.
 pseudotumor cerebri

USES: Ciprofloxacin ophthalmic solution is used to treat bacterial

infections of the eye including conjunctivitis (pinkeye; infection of the
membrane that covers the outside of the eyeball and the inside of the
eyelid) and corneal ulcers (infection and loss of tissue in the clear front
part of the eye).

GATIFLOXACIN:
Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone
family, that like other members of that family, inhibits the bacterial
enzymes DNA gyrase and topoisomerase IV.
SIDE EFFECTS:
  red, irritated, itchy, or teary eyes
 blurred vision
 eye pain
 eye discharge
 swollen eyelids
 broken blood vessels in the eyes
 headache
 unpleasant taste

CONTRAINDICATIONS:
 Fungal infection. Prolonged use of gatifloxacin ophthalmic
preparations may result in overgrowth of nonsusceptible organisms.
 Quinolone hypersensitivity.
 Pregnancy.
 Breast-feeding.

ROUTE OF ADMINISTRATIONS:
Gatifloxacin is for topical ophthalmic use only.
USES:
Gatifloxacin ophthalmic solution is used to treat bacterial conjunctivitis
(pinkeye; infection of the membrane that covers the outside of the
eyeballs and the inside of the eyelids) in adults and children 1 year of
age and older.
REFFERENCES: www.webmd.com
www.medlineplus.gov