DRUG STUDY

Ceftriaxone 1g IVTT Antibiotics Ceftriaxone is used for the Ceftriaxone is used for the Hypersensitive to • Nurse should
treatment of the infections treatment of the infections cephalosporins, penicillins advise the
(respiratory, skin, soft tissue, (respiratory, skin, soft tissue, UTI, andrelatedantibiotics. patient to
UTI, ENT) caused by susceptible promptly report
ENT) caused by susceptible organisms. Organisms that are sign of adverse
organisms.11 Organisms generally susceptible to reaction
that are generally ceftriaxone include S. • Nurse should
susceptible to ceftriaxone pneumoniae, S. pyogenes (group instruct patient
include S. pneumoniae, A beta-hemolytic streptococci), to report pain
S. pyogenes (group A coagulase-negative • Nurse should
betahemolytic staphylococci, Some advise patient to
streptococci), Enterobacter spp, H. influenzae, report
coagulasenegative N. gonorrhoeae, P. mirabilis, E. immediately
staphylococci, Some coli, Klebsiella spp, M. catarrhalis, when loose stool
Enterobacter spp, H. B. burgdorferi, and some oral or
influenzae, N. gonorrhoeae, anaerobes. diarrhea occurs
P. mirabilis, E. coli,
Klebsiella spp, M.
catarrhalis, B. burgdorferi,
and some oral
anaerobes.1
Ranitidine 50 g IVTT Histamine H2 After a meal, the hormone This drug is used alone or with Ranitidine is contraindicated Before
Antagonists gastrin, produced by cells in concomitant antacids for the for patients known to have • Assess patient for
the lining of the stomach, following conditions: short-term hypersensitivity to the drug epigastric or
stimulates the release of treatment of active duodenal or any of the ingredients abdominal pain
histamine, which then binds ulcer, treating gastric acid Acute polyuria, treatment and frank or
to histamine H2 receptors, hypersecretion due to Zollinger- with ranidine may mask the occult blood in
leading to the secretion of Ellison syndrome, systemic symptoms of other gastric the stool, emesis,
gastric acid. Ranitidine mastocytosis, and other disease, raised liver enzyme or gastric aspirate
reduces the secretion of conditions that may may occur with high doses. • Assess geriatric
gastric acid by reversible pathologically raise gastric acid and debilitated
binding to histamine (H2) levels. It also used in the short patients routinely
receptors, which are found term treatment of active benign for confusion.
on gastric parietal cells. This gastric ulcers and maintenance report
process leads to the therapy of gastric ulcers at a promptly
inhibition of histamine reduced dose. In addition to the During
binding to this receptor, above, ranitidine can be used for • Administer over
causing the reduction of the treatment of GERD at least 5 mins.
gastric acid secretion. The symptoms, treatment of erosive Rapid
relief of gastric-acid related administration
 symptoms can occur as may

soon as 60 minutes after esophagitis (endoscopically cause hypotension

administration of a single dose, diagnosed) and the maintenance of and arrhythmias.
and the effects can last from 4-10 gastric or duodenal ulcer healing. After
hours, providing fast and effective • Ranitidine may cause
symptomatic relief. false positive results
for urine protein: test
with sulfos alicylic
scid
• Administer with
meals or immediately
afterward and at
bedtime to prolong
effect