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    Product Information Sheet Corning Gentamicin Sulfate

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    Miss Hermione
    Gentamicin sulfate is an aminoglycoside antibiotic produced by bacteria that prevents protein synthesis in both gram-positive and gram-negative bacteria. It works by binding to the 30S ribosomal subunit and blocking translocation of peptidyl-tRNA. Gentamicin sulfate is available as a liquid or powder, has a molecular weight of 575.64, and is used in research to inhibit mycoplasma growth in tissue culture at working concentrations of 50 μg/mL for powder or 1 mL/L for liquid. It should be stored at 15-30°C for liquid or 2-8°C for powder and protected from light.

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    Product Information Sheet Corning Gentamicin Sulfate

    Uploaded by

    Miss Hermione
    9 views2 pages
    Gentamicin sulfate is an aminoglycoside antibiotic produced by bacteria that prevents protein synthesis in both gram-positive and gram-negative bacteria. It works by binding to the 30S ribosomal subunit and blocking translocation of peptidyl-tRNA. Gentamicin sulfate is available as a liquid or powder, has a molecular weight of 575.64, and is used in research to inhibit mycoplasma growth in tissue culture at working concentrations of 50 μg/mL for powder or 1 mL/L for liquid. It should be stored at 15-30°C for liquid or 2-8°C for powder and protected from light.

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    Product-Information-Sheet-Corning-Gentamicin-Sulfate

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    Gentamicin sulfate is an aminoglycoside antibiotic produced by bacteria that prevents protein synthesis in both gram-positive and gram-negative bacteria. It works by binding to the 30S ribosomal subunit and blocking translocation of peptidyl-tRNA. Gentamicin sulfate is available as a liquid or powder, has a molecular weight of 575.64, and is used in research to inhibit mycoplasma growth in tissue culture at working concentrations of 50 μg/mL for powder or 1 mL/L for liquid. It should be stored at 15-30°C for liquid or 2-8°C for powder and protected from light.

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    © All Rights Reserved
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    9 views2 pages

    Product Information Sheet Corning Gentamicin Sulfate

    Uploaded by

    Miss Hermione
    Gentamicin sulfate is an aminoglycoside antibiotic produced by bacteria that prevents protein synthesis in both gram-positive and gram-negative bacteria. It works by binding to the 30S ribosomal subunit and blocking translocation of peptidyl-tRNA. Gentamicin sulfate is available as a liquid or powder, has a molecular weight of 575.64, and is used in research to inhibit mycoplasma growth in tissue culture at working concentrations of 50 μg/mL for powder or 1 mL/L for liquid. It should be stored at 15-30°C for liquid or 2-8°C for powder and protected from light.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    of 2

    Gentamicin Sulfate

    Molecular structure

    Product Description
    Gentamicin, also known as gentiomycin C, is an aminoglycoside, which is naturally produced by Gram-
    negative bacteria. This antibiotic functions by preventing protein synthesis. Gentamicin sulfate prevents
    the growth of both Gram positive and Gram negative bacteria, in vivo and in vitro. In tissue culture,
    gentamicin sulfate is used to inhibit the growth of various strains of mycoplasma.

    Product Specification
    Mode of Action: Gentamicin causes codon misreading by binding to the 30S ribosomal
    subunit, blocking the translocation of peptidyl-tRNA from the acceptor
    site to the donor site. The bactericidal effect of gentamicin on
    Pseudomonas aeruginosa is exerted by the binding of gentamicin to the
    outer membrane, where it displaces natural cations, destabilizes the
    membrane, and forms holes in the cell surface.

    Conferred Resistance: high-level aminoglycoside resistance in gram-negative bacteria

    Molecular weight: 575.64

    Formula: C21H43N5O7•H2SO4

    Appearance: Liquid: yellow liquid

    Powder: off white powder

    Working Concentration: Powder: 50 μg/mL


    Liquid: 1 mL/Litre

    Solubility: Powder: H20

    Page 1 of 2
    Life Science Production, a Division of Life Science Group Ltd.
    Tel: +44 (0) 1234 889180; Email: sales@lifesciencegroup.co.uk
    Web: www.lifescienceproduction.co.uk
    Storage and Stability: Liquid: 15°C to 30°C
    Powder: 2°C to 8°C
    Protect from light

    Ordering information
    Cat. No. Description Unit Size Qty/Pk

    30-005 CR Gentamicin Sulfate liquid 50 mg/mL solution 10 x 10 mL 1

    61-098 RA Gentamicin Sulphate Powder 0.1 g 1

    61-098-RF Gentamicin Sulphate Powder 1g 1

    For Research use only. Not approved for human or veterinary use, for application to humans or
    animals, or for use in clinical or in vitro procedures.

    Support
    Life Science Production is a division of Life Science Group Ltd.
    Life Science Production is ISIA Traceability Certified
    Life Science Group Ltd is an ISO 9001:2015 Certified company

    To learn more, contact us:


    Telephone: +44 (0) 1234 889180
    Email: sales@lifesciencegroup.co.uk
    Website: www.lifescienceproduction.co.uk
    Address: PO Box 1519, Bedford, United Kingdom

    Page 2 of 2
    Life Science Production, a Division of Life Science Group Ltd.
    Tel: +44 (0) 1234 889180; Email: sales@lifesciencegroup.co.uk
    Web: www.lifescienceproduction.co.uk

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