Kristyn Joy D.

Atangen October 26, 2020

BSN IV/ Section -A/ Group-D Josephine Minger
DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT / SIDE NURSING
CONTRAINDICATION EFFECTS RESPONSIBILITIES

GENERIC INDICATIONS CNS  If large doses are given,

CEFTRIAXONE Inhibits cell-wall synthesis, Septicemia, Susceptible bacterial Pseudomembranous colitis, therapy is prolonged, or
promoting osmotic instability; infections diarrhea patients is at high risk,
BRAND usually bactericidal monitor patient for s/s of
ROCEPHIN CONTRAINDICATION HEMATOLOGIC super infection
Contraindicated in patients Esinophilia, Thrombocytosis,  Drug is commonly used in
CLASSIFICATION hypersensitive to drug or other Leukopenia home antibiotic programs for
SOURCE: cephalosporins. Use cautiously in outpatient treatment of serious
THERAPEUTIC patients hypersensitive to SKIN infections, such as
ANTIBIOTIC Karch, A. M., & Lippincott penecillin because of possibility of Pain, Induration, Tenderness at osteomyelitis & community
Williams & Wilkins. cross- sensitivity with other beta- injection site, Rash acquired pneumonia
PHARMACOLOGIC (2013). 2013 Lippincott's nursing lactam antibiotics  Don’t confuse drug with other
THIRD- GENERATION drug guide. Philadelphia: Wolters  May increase alkaline cephalosporins that sound
CEPHALOSPORIN Kluwer Health/Lippincott DRUG TO DRUG phosphatase, ALT, AST, alike
Williams & Wilkins. INTERACTION bilirubin, BUN, and LDH  Tell patient SO to report
DOSAGE Aminoglycosides, P. aeruginosa & levels adverse reactions promptly
5 mg/kg Enterobacteriaceae, Probenecid,  May increase eosinophil &  Instruct patient SO to report
Warfarin platelet counts discomfort at I.V. insertion
ROUTE  May increase PTT, PT, & site
I.V. INR  Teach patient SO receiving
 May falsely increase serum or home care how to prepare &
urine creatinine level in tests give drug
using Jaffe reaction  If home care patient is
diabetic & is testing his urine
for glucose, tell him drug may
affect results of cupric sulfate
test; he should use an
enzymatic test instead
 Tell patient SO to notify
prescriber about loose stools
or diarrhea
Kristyn Joy D. Atangen October 26, 2020
BSN IV/ Section -A/ Group-D Josephine Minger

DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT / SIDE NURSING

CONTRAINDICATION EFFECTS RESPONSIBILITIES

GENERIC Inhibits toxin A- mediated INDICATIONS CNS  Assess patient for abdominal
ENTEROL diarrhea, intestinal inflammation & Indicated in the specific and Hypotension, Fever, Nausea, distention, presence of bowel
histological damage by reducing symptomatic treatment of bacterial Emesis, Headache sounds, and usual pattern of
BRAND toxin A- receptor binding or protozoal diarrhea and enteritis bowel function.
SACCHAROMYCES caused by susceptible GI  Assess color, consistency, and
BOULARDII organisms. Enterol products are Colitis, Bloating, Constipation, amount of stool produced.
well tolerated, have a very low Flatulence  Instruct patient SO to take as
CLASSIFICATION SOURCE: incidence of adverse reactions. directed.
GU
THERAPEUTIC Hossain MN, Afrin S, Humayun S, CONTRAINDICATION Proctitis, Anal pruritus,
ANTIDIARRHEALS Ahmed MM, Saha BK. Front Nutr. In general M.O. drugs, tyramine Staphylococcic enteritis
2020; 7:27. Epub 2020 Apr 3. containing foods & indirectly
PHARMACOLOGIC acting sympathomimetic amines MUSCULOSKELETAL
PHARMACOKINETICS are contraindicated or should be Arthralgia
used with caution in patients
DOSAGE receiving enterol RESPIRATORY
2. 5- 5.0 ml Dyspnea

ROUTE SKIN
ORAL Vesicular morbilliform rash,
Flushing

DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT / SIDE NURSING

CONTRAINDICATION EFFECTS RESPONSIBILITIES
GENERIC Thought to produce analgesia & INDICATIONS EENT  For inflammatory conditions,
ASPIRIN exert its anti-inflammatory effect Thrombocytosis Tinnitus, Hearing loss rheumatic fever, &
by inhibiting prostaglandin & other thrombosis, give aspirin on a
BRAND substances that sensitize pain CONTRAINDICATION GI schedule rather than as needed
Kristyn Joy D. Atangen October 26, 2020
BSN IV/ Section -A/ Group-D Josephine Minger
ASAPHEN, ASATAB, BAYER, receptors. Drug may relieve fever Contraindicated in patients Nausea, GI bleeding, Dyspepsia,  Because enteric-coated &
ECOTRIN, EMPIRIN, through central action in the hypersensitive to drug & in those GI distress, Occult bleeding sustained release tablets are
ENTROPHEN, HALFPRIN, hypothalamic heat-regulating with NSAID-induced sensityvity slowly absorbed, they aren’t
NORWICH, NOVASEN, ST. center. In low doses, drug also reactions, G6PD deficiency or GU suitable for rapid relief of
JOSEPH, ZORPRIN appears to interfere with clotting bleeding disorder, such as Renal insufficiency acute pain, fever, or
by keeping a platelet-aggregating hemophilia, von Willebrand inflammation
CLASSIFICATION substance from forming disease, or telangiectasia HEMATOLOGIC  For patients who can’t tolerate
Prolonged bleeding time, oral drugs, ask prescriber
THERAPEUTIC DRUG TO DRUG Leukopenia, Thrombocytopenia about using aspirin rectal
NSAID SOURCE: INTERACTION suppositories
ACE inhibitors, Ammonium HEPATIC  Febrile, dehydrated children
PHARMACOLOGIC Karch, A. M., & Lippincott chloride & other urine acidifiers, Hepatitis can develop toxicity rapidly
SALICYLATE Williams & Wilkins. Antacids in high doses & other  Monitor elderly patients
(2013). 2013 Lippincott's nursing urine alkalinizers, Anticoagulant, SKIN closely because they may be
DOSAGE drug guide. Philadelphia: Wolters Beta blockers, Corticosteroids, Rash, Bruising, Urticaria more susceptible to aspirin’s
5 mg/kg Kluwer Health/Lippincott Heparin toxic effects
Williams & Wilkins.  May increase liver function  Tell patients who’s allergic to
ROUTE DRUG TO FOOD test values, blood urea tartazine to avoid aspirin
P.O. INTERACTION nitrogen, creatinine, &  Advise patient on a low salt
Caffeine potasium levels diet that 1 tablet of buffered
 May decrease platelet & aspirin contains 553 mg of
WBC counts sodium
 May falsely increase protein-  Advised patient to take drug
bound iodine level with food, milk, antacid, or
 May interfere with urine large glass of water to reduce
glucose analysis with GI reactions
Diastrix, Chemstrip uG,  Tell patient not to crush or
Clinitest, & Benidict solution; chew sustained-release or
with urinary 5- enteric-coated forms but to
hydroxyindoleacetic acid & swallow them whole
vanillylmandelic acid tests; &  Instruct patient to discard
with Gerhardt test for urine aspirin tablets that have a
acetoacetic acid strong vinegar- like odor
 Tell patient to consult
Kristyn Joy D. Atangen October 26, 2020
BSN IV/ Section -A/ Group-D Josephine Minger
prescriber if giving drug to
children for longer than 5
days or adults for longer than
10 days

DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT / SIDE NURSING

CONTRAINDICATION EFFECTS RESPONSIBILITIES
GENERIC Direct-acting trichomonicide & INDICATIONS CNS  Monitor liver function test
METRONIDAZOLE amebicide that works inside & Intestinal amebiasis Headache, Seizures, Fever, results carefully
outside the intestines. It’s thought Vertigo, Ataxia, Dizziness,  Observe patient for edema
BRAND to enter the cells of CONTRAINDICATION Syncope, Irritability  Record number & character of
FLAGYL, FLAGYL ER, microorganisms that contain Contraindicated in patients CV stools when drug is used
FLORAZOLE ER, NOVO- nitroreductase, forming unstable hypersensitive to drug or other Flattened T wave, Edema  Don’t confuse metronidazole
NIDAZOL, FLAGYL IV RTU compounds that bind to DNA & nitroimidazole derivatives with metformin
inhibit synthesis, causing cell EENT  Instruct patient SO to give
CLASSIFICATION death DRUG TO DRUG Rhinitis, Sinusitis, Pharyngitis extended-release tablets at
INTERACTION least 1 hour before or 2 hours
THERAPEUTIC Busulfan, Cimetidine, Disulfiram GI after meals but to take all
ANTIPROTOZOAL SOURCE: Nausea, Abdominal cramping or other oral forms with food to
pain, Stomatitis, Epigastric minimize GI upset
PHARMACOLOGIC Karch, A. M., & Lippincott Distress, Vomiting, Anorexia,  Inform patient SO in proper
NITROIMIDAZOLE Williams & Wilkins. Diarrhea, Dry mouth hygiene
(2013). 2013 Lippincott's nursing  Tell patient SO that she may
DOSAGE drug guide. Philadelphia: Wolters GU experience a metallic taste &
7.5 mg/kg Kluwer Health/Lippincott Vaginitis, Darkened urine, have dark or red-brown urine
Williams & Wilkins. Polyuria, Dysuria, Cystitis  Tell patient SO to report to
ROUTE prescriber symptoms of
P.O. HEMATOLOGIC candidal overgrowth
Transient leukopenia  Tell patient SO to report to
prescriber immediately any
MUSCULOSKELETAL neurologic symptoms like
Transient joint pains seizures, peripheral
neuropathy
Kristyn Joy D. Atangen October 26, 2020
BSN IV/ Section -A/ Group-D Josephine Minger
RESPIRATORY
URTI

SKIN
Rash

 May decrease WBC &

neutrophil counts
 May falsely decrease
triglyceride &
aminotransferase levels