The document summarizes homeostasis and the human urinary system. It contains multiple questions and answers about:
1) The key components of the nephron (proximal convoluted tubules, distal convoluted tubules, loop of Henle) and their locations in the kidney cortex and medulla.
2) The mechanisms of urine concentration including water reabsorption through osmosis and sodium/glucose reabsorption through active transport in different parts of the nephron.
3) Homeostatic mechanisms like sweating, shivering and hormone secretion that help regulate body temperature in cold/hot environments.
The document summarizes homeostasis and the human urinary system. It contains multiple questions and answers about:
1) The key components of the nephron (proximal convoluted tubules, distal convoluted tubules, loop of Henle) and their locations in the kidney cortex and medulla.
2) The mechanisms of urine concentration including water reabsorption through osmosis and sodium/glucose reabsorption through active transport in different parts of the nephron.
3) Homeostatic mechanisms like sweating, shivering and hormone secretion that help regulate body temperature in cold/hot environments.
The document summarizes homeostasis and the human urinary system. It contains multiple questions and answers about:
1) The key components of the nephron (proximal convoluted tubules, distal convoluted tubules, loop of Henle) and their locations in the kidney cortex and medulla.
2) The mechanisms of urine concentration including water reabsorption through osmosis and sodium/glucose reabsorption through active transport in different parts of the nephron.
3) Homeostatic mechanisms like sweating, shivering and hormone secretion that help regulate body temperature in cold/hot environments.
CHAPTER 13 HOMEOSTASIS AND THE HUMAN URINARY SYSTEM 1 The proximal convoluted tubules and distal convoluted tubules are found in the cortex, whereas the loop of Henle is found in the medulla. Formative Practice 13.1 2 Eating salty foods and drinking less water 1 Homeostasis is the regulation of the physical and chemical factors of the internal environment within a 3 Water is reabsorbed through osmosis. The normal range so that cells can function optimally. reabsorption of sodium ions and glucose occurs through active transport. The mechanism of homeostasis occurs by negative feedback: 4 The individual does not need undergo • A values that exceeds the normal range is haemodialysis. The individual only needs to reduce reduced back to normal. food rich in protein and salt as well drink enough • A value that drops below the normal range is water. raised back to normal. Formative Practice 13.3 2 Mechanism of homeostasis: • Vasodilation occurs 1 Kidney stones may block the ureter and reduce the production of urine. • Sweat glands secrete sweat • Erector muscles relax – body hairs are lowered 2 Not drinking enough water and excessive intake of mineral salts such as calcium • Skeletal muscles contract and relax lesser. Body does not shiver. Summative Practice 13 • The adrenal and thyroid glands are less stimulated – metabolism rate is lowered 1 The loop of Henle can be found in the kidney medulla. 3 Excess glucose is not converted into glycogen. The glucose level in the blood rises (hyperglycaemia) 2 (a) Diluted urine in large amounts and glucose is excreted through the urine (b) Concentrated urine in small amounts (glycosuria). In this condition, the individual is considered as having diabetes mellitus. A diabetic 3 Benedict’s tests patient is constantly feeling thirsty, exhausted 4 The liver slows down cellular respiration, converts and lethargic and experiences weight loss. If left glycogen to glucose and prevents the conversion of untreated, it may lead to death. glucose to glycogen. 4 • B lood pressure rises. The baroreceptor on the 5 (a) The amino acid concentration in blood aortic arch and arterial carotid are stimulated. plasma is higher than that found in the urine. • The cardiovascular control centre in the medulla Reabsorption occurs. 100% of the amino oblongata is stimulated. acids are reabsorbed into the blood capillaries • The smooth muscles of the artery wall relax through active transport at the proximal (vasodilation), hence reducing resistance to convoluted tubule. blood flow in the blood vessels. (b) The kidney failed to function as • The cardiac muscles contract weakly. osmoregulatory organ. The water content in • Blood pressure returns to normal. the body cannot be regulated.
6 (a) • A bsence of lipase. This means less fat – Sweat glands are not stimulated. Therefore, no digestion. sweating occurs. • Absence of trypsin. This means less protein – Erector muscles contract, causing body hairs digestion. to rise. A thick layer of air is trapped on the • When insulin and glucagon are not skin surface and acts as a heat insulator that produced, the regulation of blood sugar level prevents the loss of heat through the skin. is affected. – Body shivers. The skeletal muscles contract and relax, generating heat and increasing body (b) • Reduce the intake of carbohydrates temperature. • Get an insulin injection if the blood glucose – The thyroid gland is stimulated to secrete level rises above normal. thyroxine and the adrenal gland is stimulated 7 (a) Ultrafiltration to secrete adrenaline. Thyroxine increases cell metabolism rate and adrenaline increases (b) Blood cells and plasma protein glycogen conversion into glucose. Glucose is (c) The diameter of the afferent arteriole that oxidised to yield heat energy. carries blood into the glomerulus is larger 9 • There is less oxygen in the atmosphere. than the diameter of the efferent arteriole that carries blood out of it. This creates a high • The oxygen partial pressure is low. hydrostatic pressure in the glomerulus, and • There is less oxygen in the blood. pushes molecules of specific sizes such as • This is detected by the peripheral glucose and amino acid out across a two-cell chemoreceptors. Nerve impulses are generated thick wall between the capillary wall and the and sent to the respiratory and cardiovascular inner wall of the Bowman capsule. control centres, and then to the intercostal (d) Glucose was reabsorbed in the proximal muscles, diaphragm and cardiac muscles. convoluted tubule through active transport. The rate of contraction and relaxation of the intercostal muscles and diaphragm increases, (e) Animals that live in a dry environment have hence increasing the breathing (inhale/exhale) a longer loop of Henle compared to animals rate. Heartbeat also increases. living in a moist environment. This enables • More oxygen is brought to the cells and more more water to be absorbed through the loop of carbon dioxide is transported to the lungs. Henle. The result is concentrated urine. 10 • T he erector muscles relax, causing the body Essay Questions hairs to lean towards the skin surface. 8 • T he body temperature of the worker drops after • Body hairs trap a thin layer of air allowing more sitting in a cold room for 6 hours. heat to be released to the surrounding. • The thermoreceptors on the skin receive stimuli • Sweat glands secrete sweat. When the sweat and transmit nerve impulses to the temperature evaporates, heat is lost to the surrounding. control centre in the hypothalamus through 11 (a) (i) The optimum temperature for all afferent nerves. enzyme-catalysed chemical reactions • A negative feedback mechanism occurs: is 37 °C. If the body temperature rises, – Vasoconstriction takes place. This reduces the enzyme-controlled metabolic reactions flow of blood to the skin surface and hence will be affected because the enzymes will less heat flows to the surrounding. become denatured.
(ii) • T he erector muscles of the skin • As a consequence, blood osmotic pressure contract, raising body hairs. A layer drops and returns to the normal range. of air trapped on the skin surface, • Low osmotic pressure creates a negative functions as an insulator. feedback mechanism that reduces the • When stimulated, skeletal muscles activities of the osmoreceptor cells in the contract and relax more. The body hypothalamus. shivers and heat is generated. • This will then cause the pituitary gland to (b) • Protein is digested into amino acids. cease secreting more ADH. • Excess amino acids are toxic and cannot be Enrichment stored. • Through deamination, the nitrogenous part 12 Seawater fishes do not experience dehydration of amino acids is converted to urea while although sea water is hypertonic to the body fluids the non-nitrogenous (carbon chain) part is due to homeostasis. Through homeostasis, most converted to glycogen or fat for storage. water is reabsorbed into the blood. Only a small amount of concentrated urine is excreted. Fishes • Urea is a nitrogenous waste product that also drink a lot of sea water to replace water loss. needs to be excreted through the urine. Excess salt is expelled through specialised cells • Since the urea concentration is high in a found on the gills, that is, chloride cells. All of these person who ate too much protein-rich foods, maintain the osmotic blood pressure of the fish so urea needs a lot of water to be excreted. that dehydration does not occur. • Therefore, he/she will pass urine frequently. 13 Drugs in the bloodstream are secreted into the (c) • W hen a person drinks too little water, the renal tubule and excreted through urine. By testing blood osmotic pressure will increase above the presence of drugs in urine, we can determine normal levels. whether a person is taking drugs or not. • The osmoreceptor in the hypothalamus is 14 In applying the silicone nanotechnology to produce stimulated. Nerve impulses are transmitted a semipermeable membrane filter that lasts long, to the pituitary gland to secrete more the following should be taken into account: antidiuretic hormone (ADH) into the blood. • The apparatus does not require installation of a • A high concentration of ADH increases the tube. permeability of the distal convoluted tubule • The apparatus must be small and can be inserted and collecting duct walls. into the body without triggering any rejection from • More water is reabsorbed from the filtrate the immune system into the blood. • Able to carry out ultrafiltration process, remove • Urine becomes more concentrated and only all toxins and reabsorb all substances needed by a small amount is excreted. the body.