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BIOL

 3290  –  MEDICINAL  &  HALLUCINOGENIC  PLANTS  –  SUMMER  2020  


COURSE  CALENDAR  DESCRIPTION  AND  DISCLAIMER:  
A  botanical  and  historical  survey  of  medicinal,  hallucinogenic  and  poisonous  plants  used  in  various  
cultures.    
This  course  is  not  intended  as  a  guide  to  the  personal  use  of  medicinal,  hallucinogenic  or  poisonous  
plants.  Ingestion  or  other  uses  of  plant  products  discussed  in  this  course  can  be  dangerous,  even  fatal.  
INSTRUCTOR:  
Dr.  N.  Kenkel,  Professor  
Email:  norman.kenkel@umanitoba.ca  
COURSE  DELIVERY  AND  MATERIALS:  
All  Summer  Session  2020  courses  (both  lectures  and  exams)  at  the  University  of  Manitoba  are  
delivered  on-­‐line  via  UM  Learn.  BIOL  3290  is  delivered  in  “self-­‐study”  format,  foregoing  video  
lectures.  Students  are  provided  with  comprehensive  Course  Notes  and  Lecture  Slides  (as  PDF  
documents),  available  through  UM  Learn.  For  each  of  the  20  lectures,  students  are  encouraged  to  
self-­‐study  the  appropriate  Course  Notes  and  Lecture  Slides  during  the  assigned  class  time  (9:00  –  
10:30  AM,  Monday  to  Friday;  refer  to  the  Lecture  Schedule  on  page  2).  Please  direct  questions  
related  to  the  lecture  material  to  me  via  email  at  norman.kenkel@umanitoba.ca  
GRADING  SCHEME:    
• Research  Quiz  (10%):  Monday,  June  8  2020  from  9:00-­‐9:15  AM  (15  minutes,  9  questions).    
• Midterm  Exam  (35%):  Monday,  June  15  2020  from  9:00-­‐10:15  AM  (75  minutes,  66  questions).    
• Final  Examination  (55%):  date  and  time  TBA,  week  of  July  6-­‐10  (2  hours,  102  questions).  
All  examination  questions  are  MULTIPLE  CHOICE,  and  have  only  ONE  correct  answer.    
All  examinations  are  on-­‐line  and  MUST  be  accessed  through  UM  Learn  on  the  stated  date  and  time  –  
no  exceptions.  Make  sure  you  have  a  reliable  internet  connection  when  accessing  these  exams.      
MATERIAL  COVERED  ON  EXAMS:  
• Research  Quiz  (9  questions):  Material  from  the  Research  Project  (see  page  4  for  details).  
• Midterm  Examination  (66  questions):  Material  from  Lectures  1-­‐9  (see  page  2).    
• Final  Examination  (102  questions):  Material  from  Lectures  10-­‐20  (92  questions,  see  page  2),  
AND  material  from  the  5  Internet  Projects  (10  questions,  see  pages  5  and  6  for  details).    
PLAGIARISM  AND  CHEATING:  
Plagiarism,  cheating  or  impersonation  in  the  completion  of  assignments,  and  at  examinations,  are  
very  serious  offences.  Refer  to  the  University  of  Manitoba  Academic  Regulations  Section  7  
(Undergraduate  Calendar  2019-­‐2020)  for  definitions  and  penalties.      
COPYRIGHT:  
All  Course  Notes  and  Lecture  Slides  provided  in  this  course  are  subject  to  copyright  owned  by  Dr.  N.  
Kenkel.  Further  reproduction,  in  whole  or  in  part,  is  strictly  prohibited.  
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
BIOL  3290  –  MEDICINAL  AND  HALLUCINOGENIC  PLANTS  
LECTURE  &  EXAMINATION  SCHEDULE:  SUMMER  SESSION  (June  1  –  July  3,  2020)  
 

DAY     DATE       LECTURE  N UMBER  AND  TOPIC  


 
Monday   June  1         1  –  History  of  Medicinal  Plants  
Tuesday   June  2         2  –  History  of  Psychoactive  Plants  /  Plant  Biochemistry  
Wednesday   June  3         3  –  Poisonous  Fungi  a nd  Plants    
Thursday   June  4         4  –  Deterrents  from  Fungi  and  Plants  
Friday     June  5         5  –  Medicinal  Plants:  Cancer  Treatments    
 

Monday     June  8     RESEARCH  QUIZ  –  Plant  Irritants  (15  m inutes,  9:00-­‐9:15  AM,  9  questions)    
Tuesday   June  9         6  –  Medicinal  Plants:  Adaptogens,  Metabolism,  Immune  S ystem  …  
Wednesday   June  10         7  –  Medicinal  Plants:  Heart  and  Circulatory  S ystem  
Thursday   June  11     8  –  Medicinal  Plants:  Urogenital  and  Gastrointestinal  S ystem  
Friday     June  12       9  –  Medicinal  Plants:  Muscoskeletal  System  
 
 *
Monday   June  15     MIDTERM  EXAMINATION  (75  minutes,  9:00-­‐10:15  AM,  66  questions)    
Tuesday   June  16     10  –  Medicinal  Plants:  Central  Nervous  System  
Wednesday     June  17       11  –  Plant  Stimulants:  Oral  and  Smoked  Stimulants  
Thursday   June  18       12  –  Plant  Stimulants:  Amphetamines  and  Convulsants  
Friday       June  19     13  –  Plant  Stimulants:  Caffeine  
 
Monday     June  22       14  –  Plant  Depressants:  Tranquilizers  and  Opiates  
Tuesday     June  23       15  –  Plant  Depressants:  Alcohol  
Wednesday     June  24     16  –  Hallucinogens:  S erotonin  Enhancers  I  
Thursday     June  25     17  –  Hallucinogens:  S erotonin  Enhancers  II  
Friday       June  26     18  –  Hallucinogens:  Norepinephrine  and  GABA  Enhancers  
 
Monday     June  29     19  –  Hallucinogens:  Deliriants  
Tuesday     June  30     20  –  Non-­‐Alkaloid  Hallucinogens    
Wednesday     July  1     HOLIDAY:  CANADA  DAY    
Thursday     July  2     Review  and  Study  Period  
Friday       July  3     Review  and  Study  Period  
 **
M-­‐F       July  6-­‐10     FINAL  EXAMINATION  (2  Hours,  102  questions)  
__________________________________________________________________________________  
         
†      
RESEARCH  QUIZ  –  refer  to  page  4  for  more  information.
 

*
 MIDTERM  –  DISTRIBUTION  OF  QUESTIONS  (total  number  of  questions  =  66)  
History  of  Medicinal  Plants  =  8;  History  of  Psychoactive  Plants/Plant  Biochemistry  =  6;  Poisons  =  7;    
Deterrents  =  7;  Cancer  Treatments  =  10;  Adaptogens,  Ophthalmology,  Metabolism  &  Immune  System  =  8;    
Heart  &  Circulatory  System  =  8;  Gastrointestinal  &  Urogenital  System  =  6;  Muscoskeletal  System  =  6.  
 
**  
FINAL  EXAM  –  DISTRIBUTION  OF  QUESTIONS  (total  number  of  questions  =  102)  
Central  Nervous  System  =  6;  Oral  &  Smoked  Stimulants  =  12;  Stimulants:  Amphetamines  &  Convulsants  =  8;    
Stimulants:  Caffeine  =  8;  Depressants:  Tranquilizers  &  Opiates  =  10;  Depressants:  A lcohol  =  8;    
Hallucinogens:  Serotonin  Enhancers  =  12;  Hallucinogens:  Nonepinephrine  &  GABA  Enhancers  =  8;    
Hallucinogens:  Deliriants  =  8;  Non-­‐Alkaloid  Hallucinogens  =  12;    
Internet  Projects  1  to  5  (refer  to  pages  5-­‐6  for  more  information)  =  10.    
 
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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
EXAMINATIONS  
Students  are  required  to  write  ALL  THREE  examinations  in  this  course  (i.e.  Research  Quiz,  Midterm  
Examination,  and  Final  Examination)  during  the  scheduled  times.  There  are  no  exceptions  to  this  
requirement,  under  any  circumstances.  Failure  to  write  an  exam  will  result  in  a  grade  of  0%.  Failure  
to  write  the  Final  Examination  will  result  in  a  course  letter  grade  of  “F  (No  Paper)”.    
All  examinations  are  accessible  via  the  Internet  (through  UM  Learn),  and  MUST  be  written  during  the  
following  scheduled  exam  times:  
 

RESEARCH  QUIZ  (10%):  Monday,  June  8  2020  (9:00-­‐9:15  AM,  15  minutes).  
MIDTERM  EXAMINATION  (35%):  Monday,  June  15  2020  (9:00-­‐10:15  AM,  75  minutes).  
FINAL  EXAMINATION  (55%):  date  and  time  TBA,  week  of  July  6-­‐10  (2  hours).  
 
Missed  Final  Examination:    
If  you  miss  the  final  exam  for  personal  or  medical  reasons,  DO  NOT  REPORT  TO  YOUR  INSTRUCTOR.  
The  official  policy  of  the  University  of  Manitoba  regarding  missed  final  exams  is  given  below  (from  
http://umanitoba.ca/student/records/finals/682.html):  
If  you  miss  a  final  examination  for  medical  or  compassionate  reasons,  you  MAY  be  granted  a  deferred  examination.  Applications  for  
a  deferred  examination  after  the  examination  h as  been  missed  MUST  be  filed  w ithin  48  hours  of  the  d ate  of  the  missed  examination.  
A  medical  certificate  or  otherwise  appropriate  documentation  may  be  required.  
Requests  for  deferred  examinations  are  made  to  the  student’s  faculty,  s chool,  or  academic  advising  office.  D eferred  examinations  will  
normally  take  place  within  30  working  days  from  the  end  of  the  examination  series  from  which  the  examination  was  deferred.  Writing  a  
make-­‐up  test  at  your  convenience  may  not  be  a n  o ption.  
Please  note  t hat  students  must  remain  available  until  all  exam  and  test  obligations  have  been  fulfilled.  Travel  plans  are  not  an  
acceptable  reason  t o  miss  examinations.  
Students  w ith  known  exam  conflicts  due  to  religious  o bservance,  participation  in  specific  scholastic  a nd  a thletic  events,  or  a  m edical  
condition  may  request  a  deferred  examination.  Applications  for  a  deferred  examination  due  t o  a  known  conflict,  as  indicated  here,  
must  be  filed  20  working  d ays  PRIOR  to  the  date  of  the  scheduled  exam.  Travel  plans  are  not  an  acceptable  reason  for  missing  an  
exam.  
For  more  information  on  specific  regulations  and  requirements  for  t his  course,  visit:  
http://umanitoba.ca/faculties/science/undergrad/resources/899.html  
 
 

ACADEMIC  DISHONESTY  
Academic  dishonesty  (“cheating”)  takes  many  forms,  and  includes  unauthorized  communications  and  
sharing  of  materials  with  others  when  writing  online  examinations.  Please  be  aware  that  online  
examinations  must  be  approached  with  the  same  obligation  to  academic  integrity  as  exams  in  any  
other  format.      
 
Academic  dishonesty  is  not  tolerated  at  the  University  of  Manitoba.  
The  consequences  of  academic  dishonesty  are  very  serious,  and  may  include:  
   
• Slowing  down  the  progression  of  your  d egree,  costing  you  time  and  money.    
• Visibility  to  potential  employers,  and  on  university/professional  school  applications.  
• Failing  grade  (F)  in  the  course,  and  possible  d isbarment  f rom  the  University.    
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
RESEARCH  PROJECT  AND  QUIZ  –  PLANT  IRRITANTS  
This  Research  Project  (topic:  Plant  Irritants)  requires  you  to  make  your  own  notes,  and  to  use  your  
notes  to  answer  questions  posed  in  the  Research  Quiz.  Three  (3)  multiple-­‐choice  questions,  for  each  
of  the  three  (3)  main  groups  below,  will  appear  on  the  RESEARCH  QUIZ  (total  of  9  questions).    
The  Research  Quiz  MUST  be  completed  online  (accessed  via  UM  Learn)  during  the  scheduled  period:  
• Date:  Monday,  June  8,  2020  
• Time:  9:00-­‐9:15  AM  (15  minutes)  
RESEARCH  PROJECT:  You  are  expected  to  summarize  information  on  the  following  3  main  groups,  
each  containing  species  that  cause  painful  and  inflammatory  irritation  to  human  skin  upon  contact:    
1.  HOGWEEDS  (genus  Heracleum)  
Research  the  following  species:  
• Giant  Hogweed  (Heracleum  mantegazzianum)  
2.  POISON  IVY  –  OAK  –  SUMAC  (genus  Toxicodendron)  
Research  the  following  four  North  American  species:  
• Poison  Ivy  (Toxicodendron  radicans)  
• Poison  Oaks  (T.  diversilobum  and  T.  pubescens)  
• Poison  Sumac  (T.  vernix)  
3.  STINGING  NETTLES  (three  genera:  Urtica,  Laportea,  and  Dendrocnide)  
Research  the  following  four  species:  
• Stinging  Nettle  (Urtica  dioica,  all  subspecies)  
• Tree  Nettle  (U.  ferox)  
• Wood  Nettle  (Laportea  canadensis)  
• Stinging  Brush  (Dendrocnide  moroides)  
For  each  of  these  genera  (and  species  listed  for  each  genus),  summarize  the  following:  
• Taxonomy:  plant  family  for  each  genus.      
• Type  of  Plant:  are  the  species  annual,  biennial  or  perennial;  herbaceous  or  woody?    
• Habitat  and  Ecology:  environmental  requirements  of  each  species.    
• Distribution:  both  native  and  human-­‐introduced  distributions  of  each  species.  
• Phytochemistry:  type  and  name  of  chemical(s)  responsible  for  skin  irritation.    
• Nature  of  Dermatological  Reaction:  how  it  occurs;  symptoms,  longevity,  severity,  etc.    
• Treatment:  methods  for  alleviating  symptoms  of  dermatological  reaction.      
Using  appropriate  and  reliable  Internet  and/or  Library  resources  to  compile  this  information.  
Wikipedia  entries  for  these  plants  (and  associated  links,  as  appropriate)  are  recommended.    

Here  is  an  example  of  a  question  that  might  appear  on  the  Research  Quiz:  
           The  tree  nettle  (Urtica  ferox)  is  native  to:  
             •    (a)  North  America              (b)  Europe                (c)  Australia                (d)  New  Zealand                  (e)  India.  
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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
INTERNET  PROJECTS  (FINAL  EXAMINATION)  
For  the  Final  Examination,  you  are  responsible  for  all  material  covered  in  Lectures  10  to  20  of  the  
BIOL  3290  Course  Notes  and  Slides.  You  are  ALSO  responsible  for  Internet  Project  material:  
Two  (2)  multiple-­‐choice  questions  from  each  of  five  (5)  Internet  Projects  will  appear  on  the  Final  
Examination  (10  questions  in  total).  
Each  Internet  Project  consists  of  a  series  of  questions  regarding  a  medicinally  important  plant  species  
(one  not  discussed  in  the  Course  Notes).  Students  must  obtain  answers  to  the  questions  posed  (i.e.  
make  your  own  notes),  using  Internet  or  Library  resources.  In  answering  the  questions,  be  sure  to  use  
reliable  Internet  sites.  Wikipedia  entries  for  the  species  are  highly  recommended.    

For  each  Internet  Project,  you  are  expected  to  make  your  own  notes  and  study  your  notes  for  the  
Final  Examination.  
 
NOTE:  These  are  NOT  Assignments  to  hand  in  to  your  professor  for  grading.  
 
 
 
Here  are  the  five  INTERNET  PROJECTS  (compile  answers  to  all  of  the  following  questions):  
 

1.  ARNICA  (Arnica  montana)  


       BOTANICAL  INFORMATION:    
• To  which  p lant  family  does  this  species  b elong?    
• What  type  of  p lant  is  it:  (a)  h erbaceous  or  woody;  (b)  h erb,  shrub  or  tree;  (c)  annual,  b iennial  or  
perennial?  
• What  is  its  native  d istribution?  
       USE  AS  A  MEDICINAL  PLANT:  
• Which  part  of  the  p lant  is  used  for  medicinal  purposes?    
• For  what  a ilment(s)  is  this  p lant  recommended?    
• Does  recent  clinical  research  support  its  efficacy?  

2.  PSYLLIUM  (Plantago  ovata)  


         BOTANICAL  INFORMATION:    
• What  type  of  p lant  is  it:  (a)  h erbaceous  or  woody;  (b)  h erb,  shrub  or  tree;  (c)  annual,  b iennial  or  
perennial?  
• What  is  its  native  d istribution?  
         MODERN  UTILIZATION  AS  A  MEDICINAL  PLANT:    
• What  part  of  the  p lant  is  used  for  medicinal  purposes?  
• For  what  medicinal  and/or  therapeutic  use  is  psyllium  recommended  ( MAJOR  use  only)?    
 
 
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
 

3.  RESIN  SPURGE  (Euphorbia  resinifera)  


         BOTANICAL  INFORMATION:    
• To  which  family  does  this  species  b elong?  
• What  type  of  p lant  is  it:  (a)  h erbaceous  or  woody;  (b)  h erb,  shrub  or  tree;  (c)  annual,  b iennial  or  
perennial?  
• What  is  its  native  d istribution?  
         MODERN  UTILIZATION  AS  A  MEDICINAL  PLANT:    
• What  is  the  medicinal  secondary  product  found  in  this  plant?  
• This  compound  is  undergoing  clinical  trials:  for  what  p urpose?    

4.  KRATOM  (Mitragyna  speciosa)  


         BOTANICAL  INFORMATION:    
• To  which  family  does  this  species  b elong?  
• What  type  of  p lant  is  it:  (a)  h erbaceous  or  woody;  (b)  h erb,  shrub  or  tree;  (c)  annual,  b iennial  or  
perennial?  
• What  is  its  native  d istribution?  
       HISTORY  OF  USE:  
• What  part  of  this  p lant  species  is  used?    
• What  is  the  major  psychoactive  chemical  compound  present  in  this  plant  species?  
• What  is  kratom  used  for,  and  what  are  its  effects?  

5.  WAIRUAKOHU  (Radula  marginata)  


         BOTANICAL  INFORMATION:    
• Which  Plant  Division  does  this  species  b elong  to  (provide  s cientific  and  common  names  for  the  
Division)?  
• What  are  the  main  characteristics  of  p lants  b elonging  to  this  Division?  
• What  is  the  native  distribution  of  this  species?  
       HISTORY  OF  USE:  
• Which  group  of  indigenous  p eoples  used  this  species  a s  a  herbal  medicine?    
• What  is  the  major  psychoactive  chemical  found  in  this  species,  and  what  are  its  effects?  
• The  psychoactive  in  this  species  is  similar  to  which  group  of  psychoactive  chemicals  d iscussed  in  this  
course?  
 
Here  is  an  example  of  a  question  that  might  appear  on  the  Final  Examination:  
 

           Arnica  (Arnica  montana)  is  a  member  of  the  __________  family.  


             •    (a)  Carrot  [Apiaceae]                          (b)  Legume  [Fabaceae]                          (c)  Mint  [Lamiaceae]                  
                     (d)  Aster  [Asteraceae]                      (e)  Rose  [Rosaceae].  
 
 
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
 
FINAL  GRADES  
 
Final  grades  in  this  course  (and  all  other  courses  at  the  University)  use  the  official  University  of  
Manitoba  ranking  system,  http://umanitoba.ca/student/records/grades/686.html:    
   
Letter  Grade                               Grade  Point  Value                              Description              
 
A+       4.5     Exceptional  
A       4.0     Excellent  
B+       3.5     Very  Good  
B       3.0     Good  
C+       2.5     Satisfactory  
C       2.0     Adequate  
D       1.0     Marginal  
F       0.0     Failure  
 
Final  grades  are  expressed  as  letters,  ranging  from  D,  the  lowest  passing  grade,  to  A +  the  h ighest.  Each  letter  grade  has  an  
assigned  numerical  value,  which  is  used  to  calculate  grade  p oint  averages.  
 
 
 
 
Note  that  this  is  a  relative  scale,  in  which  letter  grades  are  determined  based  on  a    
student’s  ranking  relative  to  other  students  in  the  class.  
 
 
In  this  course,  the  following  grading  system  is  used:  
 
A+    ≥  90%                                    A  =  80  –  89.9%                B+  =  74  –  79.9%                  B  =  68  –  73.9%  
C+  =  62  –  67.9%              C  =  56  –  61.9%                  D  =  50  –  55.9%                      F  <  50%  
 
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
USE  OF  COPYRIGHTED  MATERIAL  
All  students  are  required  to  respect  copyright  as  per  Canada’s  Copyright  Act.  S taff  and  s tudents  p lay  a  key  role  
in  the  University’s  copyright  compliance,  as  we  balance  user  rights  for  educational  purposes  with  the  rights  of  
content  creators  from  around  the  world.  
• The  content  used  in  this  course  is  appropriately  acknowledged  and  copied  in  accordance  with  copyright  laws  
and  University  guidelines.  
• Copyrighted  works,  including  those  created  b y  Dr.  N.  Kenkel,  are  made  available  for  private  s tudy  and  
research  and  m ust  not  be  distributed  in  any  format  w ithout  permission.  
• Do  not  upload  copyrighted  works  to  a  learning  management  s ystem  (such  as  UM  Learn),  or  any  website,  
unless  an  exception  to  the  Copyright  Act  applies  or  written  p ermission  has  b een  confirmed.  
• For  more  information,  see  the  University’s  Copyright  Office  website  at  http://umanitoba.ca/copyright/  or  
contact  um_copyright@umanitoba.ca.  
 
COURSE  LECTURES  AND  NOTES    
• Dr.  N.  Kenkel  holds  copyright  over  a ll  course  materials,  presentations  and  lectures  p ertaining  to  this  course.  
• No  video  or  photographic  recording  of  course  m aterials  is  allowed  in  any  format,  openly  or  surreptitiously,  
in  w hole  or  in  part,  w ithout  explicit  permission  from  Dr.  N.  Kenkel.  
• Digital  course  materials  are  for  the  student’s  private  study  and  research  only.  
 
 
USE  OF  TECHNOLOGY  
• Technology  is  to  b e  used  in  a  responsible,  ethical  and  legal  manner.  
• The  following  a ctivities  are  not  p ermitted  during  exam  times:  electronic  messaging  and  p osting,  including  
texting,  social  n etworking,  video  or  voice  chat,  email,  wikis,  b logs,  etc..  
• Use  of  cell  phones  during  exam  times,  except  in  emergencies,  is  not  permitted.  
 
 
EXPECTATIONS  OF  STUDENTS  
• The  Research  Quiz  and  Internet  Projects  are  to  b e  completed  independently;  collaboration  is  prohibited.  
• Students  are  encouraged  to  use  email  to  ask  their  professor  questions  related  to  the  course  material  
presented.  
• The  University  of  Manitoba  fosters  a  respectful  work  a nd  learning  environment;  professors  t reat  students  
with  respect,  and  expect  t he  same  courtesy  in  return.  Please  refer  to  the  Respectful  Work  and  Learning  
Environment  Policy:  
http://umanitoba.ca/admin/governance/media/Respectful_Work_and_Learning_Environment_RWLE_Poli
cy_-­‐_2016_09_01.pdf.  
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
CLASS  (EMAIL)  COMMUNICATION    
Students  are  required  to  activate  a n  official  University  of  Manitoba  email  account,  and  must  use  this  a ccount  
for  all  email  communication  b etween  themselves  and  their  professors  and  University  employees.  The  
Electronic  Communication  with  Students  Policy  includes  the  following  policies  and  regulations    
(from    http://umanitoba.ca/admin/governance/media/Electronic_Communication_with_Students_Policy_-­‐_2013_09_01_RF.pdf  ):  

• The  University  requires  a ll  students  to  activate  an  official  University  email  a ccount.  
• The  University  authorizes  the  use  of  electronic  communication  for  official  communication  between  university  
staff  and  students,  subject  only  to  the  confidentiality  a nd  privacy  provisions  outlined  below.  
• All  students  are  expected  t o  comply  w ith  established  guidelines  and  procedures  t hat  define  the  proper  use  
of  electronic  communications  as  outlined  in  this  policy  and  in  the  University’s  Use  of  C omputer  Facilities  
Policy.  
• Certain  University  electronic  communications  m ay  be  time-­‐critical.  Students  are  responsible  for  checking  
their  University  email  account  on  a  regular  basis  in  order  t o  stay  current  w ith  University  communications.  
• In  general,  electronic  communications,  including  email,  are  not  appropriate  for  transmitting  sensitive  or  
confidential  information,  including  personal  information,  unless  an  appropriate  level  of  s ecurity  matches  its  
use  for  such  purposes:  
(a)  Confidentiality  regarding  s tudent  records  is  protected  under  FIPPA.  All  use  of  electronic  communication,  
including  use  for  s ensitive  or  confidential  information,  must  b e  consistent  with  the  University  FIPPA  and  PHIA  
Policy.  
(b)  Personal  Health  Information  should  NOT  be  transmitted  via  e lectronic  communication  at  any  t ime.  
 
When  emailing  your  professor:  
• Include  in  t he  subject  heading  a  clear  summary  of  t he  purpose  of  your  email.  
• Use  an  appropriate  and  respectful  salutation:  “Dr.  Smith”  or  “Professor  S mith”.  Avoid  using  “Mr.”,  “Ms.”  or  
“Mrs.”,  and  n ever  address  your  professor  b y  h is/her  given  name.  
• Write  your  email  in  a  clear,  professional  m anner  (i.e.  formal  English),  paying  careful  a ttention  to  grammar  
and  spelling.  
• Include  your  full  name  and  student  number,  and  indicate  the  course  you  are  e nrolled  in  ( e.g.  BIOL  3290).  
 
 
STUDENT  ACCESSIBILITY  SERVICES  (SAS)  
If  you  are  a  student  with  a  d isability,  you  may  wish  to  contact  SAS  for  academic  accommodation  support  and  
services  such  as  note-­‐taking,  interpreting,  assistive  technology  and  exam  accommodations.  Students  who  have,  
or  believe  they  may  have,  a  disability  (e.g.  medical,  h earing,  injury-­‐related,  visual,  mental  h ealth,  learning)  are  
invited  to  contact  S AS  to  arrange  a  confidential  consultation.    
http://umanitoba.ca/student/accessibility/index.html  
520  University  Centre  
(204)  474-­‐7423  
email:  student_accessibility@umanitoba.ca  

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
ACADEMIC  SUPPORT  AVAILABLE  TO  STUDENTS  
 
Writing  and  Learning  Support  
The  A cademic  Learning  Centre  (ALC)  offers  services  that  may  be  h elpful  to  you  throughout  your  a cademic  program.  The  
ALC  a lso  offers  peer  supported  study  groups  called  Supplemental  Instruction  (SI)  for  certain  courses  that  students  have  
typically  found  difficult.  In  these  study  groups,  students  can  ask  questions,  compare  notes,  discuss  content,  solve  practice  
problems,  and  d evelop  n ew  study  strategies  in  a  group-­‐learning  format.  These  A cademic  Learning  Centre  services  are  f ree  
for  U  of  M  students.  For  more  information,  please  contact  t he  A cademic  Learning  Centre:        
http://umanitoba.ca/student/academiclearning/              201  Tier  Building  (204)-­‐480-­‐1481  
 
University  of  Manitoba  Libraries  (UML)  
As  the  primary  contact  for  all  research  n eeds,  your  liaison  librarian  can  play  a  vital  role  when  completing  a cademic  papers  
and  assignments.    Liaisons  can  answer  questions  about  managing  citations,  or  locating  appropriate  resources,  and  will  
address  any  other  concerns  you  may  have  regarding  the  research  p rocess.    Liaisons  can  b e  contacted  by  email  or  phone.    A  
complete  list  of  liaison  librarians  can  b e  found  by  subject:  http://bit.ly/WcEbA1  or  name:  http://bit.ly/1tJ0bB4.  For  a  
listing  of  all  libraries,  please  consult  the  following:  http://bit.ly/1sXe6RA.  When  working  remotely,  students  can  also  
receive  h elp  online,  via  the  Ask-­‐a-­‐Librarian  chat  found  on  the  Libraries’  homepage:  www.umanitoba.ca/libraries.        
 
HEALTH  AND  WELLNESS  REFERRAL  INFORMATION  
 
Student  Counselling  Centre  (SCC)  
For  24/7  m ental  health  support,  contact  the  Mobile  Crisis  Service  at  (204)  940-­‐1781.  Contact  SCC  if  you  a re  concerned  
about  any  aspect  of  your  m ental  health,  including  anxiety,  stress,  or  depression,  o r  for  help  with  relationships  o r  other  life  
concerns.  SCC  offers  crisis  services  as  well  as  individual,  couple,  and  group  counselling.  Contact  the  Student  Counselling  
Centre  (SCC):    
http://umanitoba.ca/student/counselling/index.html        474  University  Centre  or  S207  Medical  Services    (204)  474-­‐8592    
 
Student  Support  Case  Management  (SSCM)  
Contact  the  SSCM  t eam  if  you  are  concerned  about  yourself  or  another  student  and  don’t  know  where  to  turn.  SSCM  h elps  
connect  students  with  on  and  off  campus  resources,  provides  safety  planning,  and  offers  other  support,  including  
consultation,  educational  workshops,  and  referral  to  the  STATIS  threat  assessment  t eam.  
http://umanitoba.ca/student/case-­‐manager/index.html            520  University  Centre  (204)  474-­‐7423  
 
University  Health  Service  (UHS)  
Contact  UHS  for  any  m edical  concerns,  including  m ental  h ealth  problems.  UHS  offers  a  full  range  of  medical  services  to  
students,  including  psychiatric  consultation.    
http://umanitoba.ca/student/health/      104  University  Centre      (204)  474-­‐8411    
 
Health  and  Wellness  
Contact  the  H ealth  and  Wellness  Educator  if  you  a re  interested  in  information  on  a  b road  range  of  h ealth  topics,  including  
physical  and  m ental  h ealth  concerns,  alcohol  and  substance  use  harms,  and  sexual  assault.  
Health  a nd  Wellness  Educator  http://umanitoba.ca/student/health-­‐wellness/  
469  University  Centre    (204)  295-­‐9032    
 
For  comprehensive  information  about  the  full  range  of  h ealth  and  wellness  resources  available  on  campus,  visit  the  Live  
Well  @  UofM  site:  http://umanitoba.ca/student/livewell/index.html  
 
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
UNIVERSITY  POLICIES  &  PROCEDURES    
 
Rights  and  Responsibilities  
As  a  student  of  the  University  of  Manitoba  you  have  both  rights  and  responsibilities.  Become  familiar  with  policies  and  
procedures  of  the  University,  and  Regulations  specific  to  your  faculty,  college  o r  school.  The  A cademic  Calendar  
http://umanitoba.ca/student/records/academiccalendar.html  is  one  important  source  of  information.  View  the  sections  
University  Policies  and  Procedures  and  General  Academic  Regulations.  While  all  information  contained  in  these  t wo  
sections  is  important,  the  following  information  is  highlighted:    
 
•    If  you  have  questions  a bout  your  grades,  speak  with  your  instructor.  There  is  a  process  for  term  work  a nd  final  grade  a ppeals.  See  the  
Registrar’s  Office  website  for  more  information  including  a ppeal  deadline  dates  a nd  the  appeal  form  http://umanitoba.ca/registrar/  
 
•    Students  are  expected  to  v iew  the  General  Academic  Regulation  section  o f  the  Academic  Calendar,  and  especially  the  Academic  
Integrity  regulations.  Consult  the  course  syllabus  or  a sk  your  Professor  for  additional  information  regarding  academic  integrity  in  your  
academic  work.  Visit  the  Academic  Integrity  Site  for  tools  and  support:  http://umanitoba.ca/academicintegrity/    
 
•    The  University  is  committed  to  a  respectful  work  and  learning  environment.  You  have  the  right  to  be  treated  with  respect,  and  are  
expected  to  conduct  yourself  in  a n  a ppropriate  respectful  manner.  Policies  governing  behavior  include:  
 
Respectful  Learning  Environment:  
   http://umanitoba.ca/admin/governance/governing_documents/community/230.html    
Student  D iscipline:  
   http://umanitoba.ca/admin/governance/governing_documents/students/student_discipline.html    
Violent  or  Threatening  Behaviour:  
     http://umanitoba.ca/admin/governance/governing_documents/community/669.html  
 
•    If  you  experience  sexual  a ssault  or  k now  a  member  of  the  U niversity  community  who  has,  it  is  important  to  k now  there  is  a  policy  
that  provides  information  a bout:  (a)  support  available  to  those  who  disclose,  and  (b)  process  for  reporting.  The  Sexual  Assault  policy  
may  be  found  at:    
               http://umanitoba.ca/admin/governance/governing_documents/community/230.html    
               More  information  a nd  resources  can  be  found  by  reviewing  the  Sexual  Assault  site:          
               http://umanitoba.ca/student/sexual-­‐assault/  
 
•    For  information  about  rights  and  responsibilities  regarding  Intellectual  Property  v iew  the  policy:    
               http://umanitoba.ca/admin/governance/governing_documents/community/235.html  
 
For  information  on  regulations  that  are  specific  to  your  academic  program,  read  the  section  in  the  A cademic  Calendar  and  
on  the  respective  faculty/college/school  web  site  http://umanitoba.ca/faculties/  
 
Contact  an  A cademic  Advisor  within  our  faculty/college  or  school  for  questions  about  your  academic  program  and  
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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
BIOL  3290  –  MEDICINAL  &  HALLUCINOGENIC  PLANTS  
 
COURSE  NOTES  –  TABLE  OF  CONTENTS  
 
         Page  
 
HISTORY  OF  MEDICINAL  PLANTS  .….…………………………………...……………………………….…      1  

HISTORY  OF  PSYCHOACTIVE  PLANTS:  ENTHEOGENS  …………….............................……      5  

PLANT  BIOCHEMISTRY:  SECONDARY  PRODUCTS  ….………………………………….…………….      8  

POISONOUS  FUNGI  AND  PLANTS  ……………………………………………………………………...…..              9  

DETERRENTS  FROM  FUNGI  AND  PLANTS  ………………………………………………..………....…   12  

MEDICINAL  PLANTS:  CANCER  TREATMENTS    …...…….………………………….…………….…..   16  

MEDICINAL  PLANTS:  ADAPTOGENS,  OPHTHALMOLOGY,    

               METABOLISM    &  IMMUNE  SYSTEM    …………………………………………………..….………   21  

MEDICINAL  PLANTS:  HEART  &  CIRCULATORY  SYSTEM    …..……………………………….…….   25  

MEDICINAL  PLANTS:  UROGENITAL  &  GASTROINTESTINAL  SYSTEMS  ……………………..   30  

MEDICINAL  PLANTS:  MUSCOSKELETAL  SYSTEM    ……….........………………………..…….…..   33  

MEDICINAL  PLANTS:  CENTRAL  NERVOUS  SYSTEM    ……………………………….....…..….....   35  

PLANT  STIMULANTS:  ORAL  &  SMOKED  STIMULANTS      …..…………………………….….……   39  

PLANT  STIMULANTS:  AMPHETAMINES  &  CONVULSANTS  …………………………….……….   44  

PLANT  STIMULANTS:  CAFFEINE  ………………………………………………………….……….…....….   47  

PLANT  DEPRESSANTS:  TRANQUILIZERS  AND  OPIATES  …..………………………….….…..…..   50  

PLANT  DEPRESSANTS:  ALCOHOL  …..……………………………………..…………………….….…..…..   54  

HALLUCINOGENS:  SEROTONIN  ENHANCERS    ……………..…….………………………..….……..   58  

HALLUCINOGENS:  NOREPINEPHRINE  &  GABA  ENHANCERS    …….………………….….……   65  

HALLUCINOGENS:  DELIRIANTS    ………………...…………………………………..…….…..….….……   68  

NON-­‐ALKALOID  HALLUCINOGENS    ………………...…………….…………………………….…..……   71  

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  
PREFACE  
 
 
The  material  presented  in  this  textbook  is  taken  from  a  great  many  sources,  some  of  which  are  listed  
at  the  end  of  each  chapter.  Hundreds  of  books  and  journal  articles  were  consulted  to  produce  this  
textbook,  and  the  material  was  revised,  updated  and  expanded  in  fall  2019  to  keep  it  as  current  as  
possible;  the  field  of  medical  botany  is  evolving  rapidly.      
 
The  following  books  are  essential  reading  for  those  interested  in  learning  more:  
 
nd
Lewis,  W.H.  and  M.  P.  Elvin-­‐Lewis.  2003.  Medical  botany.  2  edition.  Wiley,  New  York.  
 
Perrine,  D.  M.  1996.  The  chemistry  of  mind-­‐altering  drugs:  history,  pharmacology,  and  cultural  context.  American  Chemical  
Society,  Washington.    
 
Ratsch,  C.  2005.  The  encyclopedia  of  psychoactive  plants:  ethnopharmacology  and  its  applications.  Park  Street  Press,  
Rochester.    
 
nd
Schultes,  R.  E.,  A .  Hoffman  and  C.  Ratsch.  2001.  Plants  of  the  Gods:  t heir  sacred,  healing  and  hallucinogenic  powers.  2  
edition.  H ealing  A rts  Press,  Rochester.    
 
Sneader,  W.  2005.  Drug  discovery:  a  history.  Wiley,  Chichester.    
 
       
 
The  illustrations  used  in  this  textbook  are  copyright-­‐free.  Most  are  taken  from:  
 
Harter,  J.  (editor).  1988.  The  plant  k ingdom  compendium:  a  definitive  volume  of  more  than  2,400  copyright-­‐free  
engravings.  Bonanza  Books,  New  York.    
 
 
 
This  textbook  offers  a  botanical  and  historical  survey  of  medicinal,  hallucinogenic  and  poisonous  
plants  used  by  various  societies  and  cultures.  It  is  not  intended  as  a  guide  to  the  personal  use  of  
medicinal,  hallucinogenic  or  poisonous  plants.  The  ingestion  or  other  uses  of  many  of  the  plant  
products  discussed  here  can  be  dangerous  or  even  fatal.      
 
 
 
N.  Kenkel  
May  2020  
 
 

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©  2020  N.  Kenkel.  M aterial  reproduced  in  accordance  with  copyright  law.  Further  reproduction,  in  p art  or  in  full,  is  strictly  prohibited.  

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