TABIJE, ARVIE JAYSELLE P.

NCENHL07

DRUG DATA DRUG ACTION NURSING INTERVENTIONS

Generic Name: Methyldopa Mechanism of action not conclusively Before:
demonstrated; probably due to drug’s metabolism -check doctor’s order
Trade name: which lowers arterial BP by stimulating the alpha- -assess sensitivity to the drug, hepatic disease,
Methyldopa adrenergic receptors, which in return decreases renal failure, dialysis.
sympathetic outflow from the CNS. -assess weight, skin color, lesions, mucous
Patient’s dose: membrane color, lesions affect
250mg 1tab TID -educate client about the drug, its purpose and
importance.
Classification:
Pharmacologic-sympatholytic (centrally acting) During:
-check the label twice
Route: PO -administer at the right dose and in the right time.
-do not crush nor chew tablets, swallow whole.
-discontinue drug if Coombs positive hemolytic
anemia occurs.

After:
-monitor blood counts periodically to detect
haemolytic anemia
-monitor hepatic function, especially in the first 6-8
weeks of therapy or if unexplained fever appears
-ensure that methyldopa is not reinstated in such
patients.
-report unexplained, prolonged, general tiredness,
yellowing of the skin or eyes, fever, bruising, rash
-document and record.
 DRUG DATA DRUG ACTION NURSING INTERVENTIONS
Generic Name: Acts directly on vascular smooth muscle to cause Before:
Hydrazaline vasodilation, primarily arteriolar, decreasing -check blood pressure
peripheral resistance, maintains or increases renal -arrange for cbc, LE cell preparations, and ANA
Trade name: ad cerebral flow. titers before therapy.
Apresoline, Novo-hylazin -assess for contraindicated conditions.
Pharmacokinetics -observe the 15 rights of drug administration.
Dose: A: Rapidly absorbed from the GI tract after oral -assess bowel sounds.
5mg/hr administration. -assess voiding pattern.
D: About 90% bound to plasma proteins.
Route: M: Undergoes considerable first pass metabolism During:
IV infusion by acetylation in the GI mucosa and liver. -give oral drug with food.
E: Mainly excreted in urine as metabolites -use parenteral drug immediately after opening
Classification: ampule.
Vasodilator, Anti-hypertensive -discard discolored solutions.
-instruct to take drug exactly as prescribed.

After:
-withdraw drug gradually
-discontinue if blood dyscrasias occur.
-arrange for pyridoxine therapy if patient develops
symptoms of peripheral neuritis.
-monitor for orthostatic hypotension
-report persistent or severe constipation,
unexplained fever or malaise, muscle or joint
aching, chest pain, rash, numbness, tingling.
-do proper documentation.

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DRUG NAME DRUG ACTION NURSING INTERVENTIONS
Generic name: Blocks pain impulses in CNS inhibition of -check and verify with doctors order and kardex
Aspirin prostaglandin synthesis; antipyretic action results -observe rights in medication administration such
from vasodilation of peripheral vessels; decreases as giving the right drug to the right patient using the
Brand name: platelet aggregation. right route and at the right time.
Arthrinol, -assess skin color and presence of lesions as this
may indicate hepatotoxicity, allergy, bleeding, and
Classification: other complications.
Non-narcotic analgesics, non-steroidal -assess patient’s orientation to time and place as
inflammatory, antipyretic, anti platelet the drug may cause dizziness and confusion.
-Give drug with food or after meal if GI upset
Route: occurs.
PO -to reduce the risk of the tablet lodging in the
esophagus, give drug with full glass of water.
Dosage: -ensure that the patient does not crush and chew
Adult: 2.6-5.2 g/day (q4- q6h) the tablets as well as sustained release
Child: 90-130 mg/kg/day (q4-q6) preparations t prevent losing drugs effectivity.
-if aspirin has vinegar-like odor , do not use and
dispose.
-movital sins
-raise side rail to ensure for safety.
_monitor for signs and symptoms of drug allergy
such as difficulty of breathing, pruritus, and rashes.