I. Drug Study: Denosuma B Natalizuma B, Roflumilast

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I.

DRUG STUDY

Dosage, Drug-to-
Contra- Mechanism Adverse Nursing
Name of Drug Route and Indication Drug
indication of Action Effects Responsibility
Frequency Interaction
Generic Name: IV 15mg q Serious Contraindicat Inhibits Denosuma CNS: fever, > Do skin testing
12hr infections ed in patients protein b: headache, before
Gentamicin Sulfate caused by hypersensitiv synthesis by natalizuma lethargy, administering the
Brand Name: sensitive e to drug or binding b, seizures, drug.
strains of other directly to roflumilast: vertigo, > Evaluate
Cidomycin, Pseudomo aminoglycosi the 30S May dizziness patient’s hearing
Garamycin nas des ribosomal increase EENT: before and during
Therapeutic aeruginosa subunit; risk of ototoxicity, therapy, report if
Classification: , E. Coli, bactericidal serious blurred there are
Proteus, infection. vision, alterations in the
Antibiotics Klebsiella, Consider tinnitus hearing process.
or therapy GI: Nausea > Weigh patient
Staphylocc modification and and review renal
ocus . vomiting function studies
Leflunomid GU: before therapy
e: May nephrotoxici begins.
increase ty > Obtain blood
risk of Hematologic peak gentamicin
hematologic : anemia, level 1 hour after
toxicity, leukopenia, I.M injection
such as thrombocyto > Watch signs
pancytopeni penia, and symptoms of
a, agranulocyt superinfection.
agranulocyt osis > Therapy usually
osis, or Respiratory: continues for 7 to
thrombocyt apnea 10 stop therapy
openia. Skin: rash, and obtain new
Live - virus urticaria, specimens for
vaccines: pruritus culture and
Immunosup Other: sensitivity testing.
pressants anaphylaxis
may
enhance
adverse or
toxic effect
of live-virus
MEDICATION
vaccines.
TICKET:
Pimecrolim
us,
tacrolimus
(topical):
May
enhance
adverse or
toxic effect
of
immunosup
pressants.
Tofacitinib:
May
enhance
immunosup
pressive
effect of
tofacitinib.
Trastuzuma
b: May
enhance
neutropenic
effect of
immunosup
pressants.

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