most widely used suppository base:

cocoa butter or theobroma oil

most stable use form of cocoa butter:

2 form of cocoa butter:

Alpha form

Beta form

size of vaginal suppositories:

no definite size or it varies

coitus interference:
a newborn mother cannot have sexual intercourse

1. Give a good characteristic of a paste.

• The pastes are usually less greasy, more absorptive, and stiffer in consistency than

ointments because of the large quantity of powdered ingredients present. Some pastes

consist of a single phase, such as hydrated pectin, and others consist of a thick, rigid

material that does not flow at body temperature.

• They have good adhesion on skin and less greasy. Thus when protective, rather than

therapeutic action is desired, the formulation pharmacists will favor a paste.

2. Differentiate paste vs. ointment.

• Ointments are homogenous, translucent, viscous, semi solid preparation intended for

external application to skin or mucous membranes. Ointment may be medicated or not.

Applied to mucous membrane or skin. While paste are homogeneous, semi-solid

preparations containing high concentrations of insoluble powdered substances (usually

not less than 20%) dispersed in a suitable base. Pastes are semisolid preparations intended
for application to the skin; They generally contain a larger proportion of solid material

than ointments and therefore are stiffer.

3. Give an example of paste preparation that generally absorbs serous charges.

• (e.g., Zinc Oxide Paste) The fatty pastes appear less greasy and more absorptive than

ointments by reason of a high proportion of drug substance (s) having an affinity for

water. These pastes tend to absorb serous secretions and are less penetrating and less

macerating than ointments, so that they are preferred for acute lesions that have a

tendency towards crusting, vesiculation or oozing.

Prep 9

Preparation No. 9: Zinc Gelatin

1. What is the components of glycerogelatin? Describe each.

Are plastic masses containing gelatin (15%), glycerin (40%), water (35%) and an

added medicinal substance (10%), suc as zinc oxide.

2. Give the use of glycerogelatin.

Used as a vehicle for suppositories and pessaries, its proportion is changed

according to its intended purpose.

3. What is the medicinal component of the preparation?

Zinc Gelatin is a component of mixture that is applied over ulcers and varicose

veins.

It is used as a protectant to support varicosities in the lower limbs and similar

lesions that require adhesive gel for healing.

Compose of:
Zinc oxide as an antiseptic, astringent, protective

Gelatin as Solidifying agent

Glycerin as Humectant/Preservative and;

Purified water as Vehicle/solvent

4. What is the function and use of humectant properties?

A humectant is a common moisturizing agent found in lotions, shampoos, and

other beauty products used for your hair and skin. They're known for their ability to

retain moisture while also preserving the overall properties of the product at hand.

Answer the following questions:

1. Identify the characteristic of o/w creams and w/o creams.

O/w creams contain emulsifying agent and creams are elegant drug delivery system.

W/o creams contain lipophilic emulsifying agent and used as emollient or as

cleansing agent.

2. Why creams preferred over ointment by many patients and physicians?

Creams are easier to spread and to remove.

3. A Greek pharmacist namely Claudius Galen is honored from his work called Galen’s

cerate which has similarities in cold cream?

Answer the following questions:

1. What do you called a medical device primarily used in administering suppositories

that is used to cover one or more finger?

➢ Finger cot

2. Give example and classification of suppository bases.

4 types of bases:

➢ Fatty bases (cocoa butter “Theobroma oil”

➢ Water soluble/ dispersible bases

➢ Hydrogels

➢ Glycerinated gelatin

3. Glycerin suppositories can be used for adult or infant or both. Explain your answer.

➢ Both, infants/geriatics people who cannot swallow oral medication. Glycerol

Suppositories are used for the relief of acute and temporary constipation in

infants, children and adults. But, when using this medication in any child, use

only the forms that are specially made for children. Certain brands of Fleet

Glycerin Suppositories Pediatric rectal should not be used in children. Do not

use Fleet Glycerin Suppositories Pediatric rectal in a child younger than 2

years old without the advice of a doctor.

4. What are pessaries?

Pessaries come in many shapes and sizes. The device fits into vagina and provides

support to vaginal tissues displaced by pelvic organ prolapse. The pessary is an

effective tool in the management of a number of gynecologic problems. The pessary

is most commonly used in the management of pelvic support defects such as cystocele

and rectocele. Pessaries can also be used in the treatment of stress urinary

incontinence.

A traditional herbal medicine product used for the symptomatic relief of minor digestive complaints such
as dyspepsia, flatulence and stomach cramps, based on traditional used only.

Acetic acid is used in many industrial processes for the production of substances and is often as a
chemical reagent for the production of a number of chemical compounds like acetic anhydride, ester,
vinyl acetate monomer, vinegar and many other polymeric materials.
Topics for next 2 meetings : Rizal's Cultural Roots: 1.The Ascendance of the Chinese Mestizo; 2. Rizal's
Genealogy 3.Agrarian Relations and the Friar Lands