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NCM 112: Nursing Care of Sexually-Transmitted Infections, Hiv Infections & Aids
NCM 112: Nursing Care of Sexually-Transmitted Infections, Hiv Infections & Aids
NCM 112: Nursing Care of Sexually-Transmitted Infections, Hiv Infections & Aids
NCM 112:
NURSING CARE OF SEXUALLY-TRANSMITTED INFECTIONS,
HIV INFECTIONS & AIDS
I. NURSING PROCESS IN THE CARE OF CLIENTS WITH SEXAULLY TRANSMITTED INFECTIONS
A. Health history
An STD (also known as a sexually transmitted infection [STI]) is a disease acquired through sexual contact
with an infected person.
A sexual history allows you to identify those individuals at risk for STDs, including HIV, and to identify
appropriate anatomical sites for certain STD tests.
Sexual health can greatly impact overall quality of life.
The impact of STDs on a patient’s health can range from irritating to life threatening.
Try to put patients at ease and let them know that taking a sexual history is an important part of a regular
medical exam or physical history
5 P’s
1. Partners
Remember: Never make assumptions about the patient’s sexual orientation.
It is important to determine the number and gender of your patient’s sex partners.
Ask about the partner’s risk factors, such as current or past sex partners or drug use.
2. Practices
If a patient has had more than one sex partner in the past 12 months or has had sex with a partner
who has other sex partners, you may want to explore further his or her sexual practices and
condom use (or non-use)
3. Protection from STDs
Based on the answers, you may discern which direction to take the dialogue.
Explore the subjects of abstinence, monogamy, condom use, the patient’s perception of his or
her own risk and his or her partner’s risk, and the issue of testing for STDs.
4. Past History of STDs
5. Prevention of Pregnancy
You may determine that the patient is at risk of becoming pregnant or of fathering a child. If so,
first determine if pregnancy is desired.
C. Diagnostic Tests
Gram Staining and Culture& Sensitivity- Gram stain where a sample is looked at under a
microscope after having a stain applied. A culture also helps determines what organism is
causing an infection by allowing the bacteria to grow to be better examined
and sensitivity determines how the organism can best be treated.
Nucleic Acid Amplification Test- is a technique used to detect a particular nucleic acid sequence
and thus usually to detect and identify a particular species or subspecies of organism, often
a virus or bacteria that acts as a pathogen in blood, tissue, urine, etc.
o PCR- Polymerase Chain Reaction is a fast and inexpensive technique. A very small sample
of DNA is taken and amplified large enough amount to study in detail
ELISA- Enzyme-Linked Immunosorbent Assay, is used to detect HIV infection
Western Blot- detects the specific proteins (called HIV antibodies) that indicate an HIV infection.
The Western blot is used to confirm a positive ELISA
F. Implementation
Increasing Knowledge and Preventing Spread of Disease- Discussion should emphasize that the same
behaviors that led to infection with one STD increase the risk for any other STD, including HIV. The
relative value of condoms in reducing the risk for infection with STDs should be addressed.
Reducing Anxiety- If the patient is especially apprehensive about this aspect, referral to a social worker
or other specialists may be appropriate.
Increasing Compliance
Monitoring and Managing Potential Complications
Infertility and increase risk in ectopic pregnancy
Congenital Infections. All STDs can be transmitted to infants in utero or at the time of birth
Neurosyphilis, Gonococcal Meningitis, Gonoccocal arthritis, and Syphilitic Aortitis. STDs can
cause disseminated infection. The central nervous system may be infected, as seen in cases of
neurosyphilis or gonococcal
HIV-related complications. HIV infection leads to the profound immunosuppression
characteristic of AIDS.
Pharmacologic Therapy
1. Beta- Lactams- Penicillin
2. Cephalosporins- Cefriaxone
3. Macrolide- Azithromycin
4. Tetracycline- Doxycycline
5. Nitroimidazole- Metronidazole
6. Antiviral- Acyclovir
7. TCA-Trichloroacetic Acid
8. Antiretroviral Drugs-Efavirenz, Lamivudine, Ritonavir
Nutritional Therapy
Nausea and Vomiting- SFF, bland low-fat foods, avoid greasy/spicy food, cold food than hot foods
Diarrhea-EOF, limit milk/caffeinated drinks, BRAT( Banana,Rice, Applesauce,toast),well-cooked
vegetables
Lack of Appetite- exercise,don’t drink to much before meals, variety of textures,shapes,colors
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Weight loss-dried fruits/nuts for snacks,more CHO CHON Fats, food supplements as prescribed
Mouth/Swallowing Problems- eat soft food like yogurt/mashed potato, avoid raw foods, choose
softer fruits, no acidic foods like orange & lemons
G. Evaluation
1. Exhibits knowledge about STDs and their transmission
2. Demonstrates a less anxious demeanor
a. Discusses anxieties and goals for treatment
b. Inspects self for lesions, rashes, and discharge
c. Accepts support, education, and counseling when indicated
d. Assists with sharing information about infection with sexual partners
e. Discusses risk-reduction behaviors and safer sex practices
3. Complies with treatment
4. Achieves effective treatment
5. Reports for follow-up examinations if necessary
6. Absence of complications
A. SYPHILIS
– etiologic agent: spirochete Treponema pallidum
– acquired through sexual contact or may be congenital in origin
Stages:
1. Primary Syphilis
occurs 2-3 weeks after initial inoculation with the organism.
CHANCRE- painless lesion at the site of infection
these symptoms usually resolve on spontaneously within about 2 months
2. Secondary Syphilis
spread of organism from the original chancre leads to generalized infection
the rash occurs about 2 to 8 weeks after the chancre and involves the trunk and extremities, including
the palms of the hand and the soles of the feet.
contact with these lesions can lead to transmission of the organism
generalized s/s include: lymphadenopathy, arthritis, meningitis, hair loss, fever, malaise and weight
loss
after this stage, there is a period of LATENCY -no s/s of syphilis
3. Tertiary Syphilis
20%-40% of those infected does not exhibit s/s in this final stage
slowly progressive disease with the potential to affect multiple organs
most common manifestation: aortitis and neurosyphilis as evidenced by dementia, psychosis, paresis,
stroke or meningitis
• direct identification of the spirochete obtained from the chancre lesion of primary syphilis.
• Serologic test include:
-Nontreponemal or Reagin tests such as Venereal Disease Research Laboratory (VDRL) or the Rapid
Plasma Reagin Circle Card Test (RPR-CT)
-Treponemal test such as Fluorescent Treponemal Absorption Antibody Test (FTA-ABS) and
Microhemagglutination test (MHA-TP) are used to verify that the screening test did not represent a
false-positive result.
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fails to develop because of early treatment in the primary and secondary stages.
Medical Management
• Penicillin G benzathine is the medication of choice for early/ early latent syphilis of less than 1 year
duration. IM at a single session. Doxycycline if allergic to Pen G.
Nursing Management
• Lesions of primary and secondary syphilis are highy infective : wear gloves and hand hygiene
• Educate pt to refrain from sexual contact with previous or current partners until treated
• Condoms significantly reduce the risk of transmission of syphilis and other STI
• Having multiple partners increases the risk of acquiring syphilis and other STIs
Clinical Manifestations
Women:
- both C. trachomatis and N. gonorrhoeae infections frequently do not cause symptoms in women.
- but when present, dyspareunia, dysuria, bleeding and mucopurulent cervicitis with exudates in
the endocervical canal is the most frequent finding.
- with gonorrhoea, s/s of UTI and vaginitis can often occur
- If pregnant women are infected, stillbirth, neonatal death, and premature labor may occur
Men:
- burning during urination and penile discharge.
- Pus-like discharge from the tip of the penis
- with gonorrhea report of painful, swollen testicles is also present
Complications
o Women: pelvic inflammatory disease (PID), ectopic pregnancy, endometritis, and infertility
o Men: epididymitis (leads to infertility), urethritis
o Both: arthritis or bloodstream infection may be caused by N. gonorrhoeae.
Susceptibility and resistance: Susceptibility is general. No immunity following infection and reinfection is
common.
Medical Management
-the CDC recommends dual therapy even if only gonorrhea has been laboratory proven because of
coinfection
- Serologic testing for syphilis and HIV should be offered to patients with gonorrhea or chlamydia,
because any STD increases the risk of other STD infections.
-Chlamydia: Doxycycline or azithromycin (Zithromax)
- Gonorrhea:
* ceftriaxone (Rocephin), cefixime (Suprax)
* If the patient reports a new episode of symptoms or tests are positive for gonorrhea again, the
most likely explanation is reinfection rather than treatment failure.
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Nursing Management
Gonorrhea and Chlamydia are reportable communicable diseases to ensure follow-up of the patient.
The public health department also is responsible for interviewing the patient to identify sexual contacts,
so that contact notification and screening can be initiated.
Target group for health teaching: teens and young adult population
Along with reinforcing the importance of abstinence, when appropriate, education should address
postponing the age of initial sexual exposure, limiting the number of sexual partners, and using condoms
for barrier protection.
Young women and pregnant women should also be instructed about the importance of routine screening
for chlamydia.
Patients should be discouraged from assuming that a partner is “safe” without open, honest discussion.
Non-judgmental attitudes, educational counselling, and role playing may be helpful.
Instructions also include the need for the patient to abstain from sexual intercourse until all of her sex
partners are treated (CDC, 2006a)
D. Trichomoniasis
- often called “trich”
- caused by infection with Trichomonas vaginalis, a flagellated protozoan
- more common in women than in men; may be transmitted by an asymptomatic carrier
- transmission: typically through vaginal, oral, or anal sex with an infected individual
- can also be passed from a mother to her baby at birth, as evidenced by the discovery of the parasite in
the newborn's lungs- babies born to infected mothers are more likely to have preterm delivery and low
birth weight
- In women, the most commonly infected part of the body is the lower genital tract (vulva, vagina, cervix,
or urethra)
- In men, the most commonly infected body part is the urethra
- may increase the risk of contracting HIV, in development of cervical neoplasia, postoperative infections,
adverse pregnancy outcomes, pelvic inflammatory disease (PID), and infertility
Clinical Manifestations
o Men:
- Itching or irritation inside the penis
- Burning after urination or ejaculation
- Discharge from the penis
o Women:
- Discomfort with urination;
- A change in their vaginal discharge (i.e., thin discharge or increased volume) that can be clear, white,
yellowish, or greenish with an unusual fishy smell
- An accompanying vulvitis may result, with vulvovaginal burning and itching
Medical Management
metronidazole or tinidazole (Tindamax)
- The most effective treatment for trichomoniasis
- Both partners receive a one-time loading dose or a smaller dose twice a day for 7 days
- Some patients complain of an unpleasant but transient metallic taste when taking metronidazole
- N/V, as well as a hot, flushed feeling can occur when this medication is taken with an alcoholic beverage
- Patients are strongly advised to abstain from alcohol during treatment and for 24 hours after taking
metronidazole or 72 hours after completion of a course
- of tinidazole
Prevention:
- Abstinence
- Correct use of condoms
- monogamous relationship with a partner who has been tested and has negative STD test results
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Nursing Management
Interventions to help reduce patient anxiety
Avoiding unnecessary antibiotic agents, wearing cotton underwear, and douching
treatment for woman and her partner, if indicated
Advise to reduce tissue irritation caused by scratching or wearing tight clothing
Vulvar self-examination- a good health practice for all women
Educate patients about the risks of unprotected intercourse, particularly with partners who have had
sex with others
Clinical Manifestations
- Genital herpes infections often have no symptoms, or mild symptoms that go unrecognized
- Itching and pain occur as the infected area becomes red and edematous
- macules and papules and progress to vesicles and ulcers
- The vesicular state often appears as a blister, which later coalesces, ulcerates, and encrusts. The lesions
last 2 to 12 days before crusting over.
- In women, the labia are the usual primary site, although the cervix, vagina, and perianal skin may be
affected
- In men, the glans penis, foreskin, or penile shaft is typically affected
- Inguinal lymphadenopathy
- minor temperature elevation, malaise, headache, myalgia and dysuria are often noted
- Pain is evident during the first week and then decreases
Complications
- Rarely, complications may arise from extragenital spread, such as to the buttocks, upper thighs, or even
the eyes, as a result of touching lesions and then touching other areas
- meningitis
- Neonatal herpes, although rare, can occur when an infant is exposed to HSV (HSV-2 or HSV-1) in the
genital tract during delivery. It is a serious condition that can lead to lasting neurologic disability or death
- severe emotional stress related to the diagnosis
Medical Management
Currently, there is no cure for genital herpes infection, but treatment is aimed at relieving the symptoms.
Management goals include preventing the spread of infection, making patients comfortable, decreasing
potential health risks, and initiating a counseling and education program
acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir)—anti-viral agents which can
suppress symptoms and shorten the course of the infection; are effective at reducing the duration of
lesions and preventing recurrences
Analgesics and a saline compress
Prophylactic vaccine continues to be investigated in clinical trials
Nursing Management
Assist with Sitz baths- may ease discomfort
The patient is to be alert for possible bladder distention, and to contact primary provider immediately if
she cannot void because of discomfort
Discomfort with urination can be reduced by pouring warm water over the vulva during voiding
When oral antiviral agents are prescribed, the patient is instructed to note for rash and headache
Encourage proper hand hygiene
Provide health teachings:
o Abstain from sexual intercourse during treatment for active disease
o Avoid exposure to the sun, which can cause recurrences
o Avoid self-infection by not touching lesions during an outbreak
o Use barrier methods when engaging in intercourse to provide protection against viral transmission
o Inform sexual partners of herpes diagnosis as transmission is possible even in the absence of active
lesions
o Inform obstetric care provider about the history of genital herpes. In cases of recurrence at time
of delivery, cesarean section may be considered.
o Join a support group to share solutions and experiences and hear about newer treatments
o Take medication prescribed for outbreaks and avoid occlusive ointments, strong perfumed soaps,
or bubble bath.
o Take analgesic agents to control pain during outbreaks.
o Uses the appropriate hygiene practices including hand hygiene, perineal cleanliness, gentle
washing of lesions with mild soap and running water and lightly drying lesions
o Wears loose, comfortable clothing
o Eat a balanced diet; ingest adequate fluids get adequate rest during outbreaks.
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o skin-to-skin contact; intercourse is not required for transmission to occur
o vaginal, anal, or oral sex with someone who has the virus
o The use of condoms can reduce the likelihood of transmission, but transmission can also occur
during skin-to skin contact in areas not covered by condoms
o HPV can be passed even when an infected person has no signs or symptoms
Complications
- Oral and upper respiratory lesions
- Certain strains of HPV can cause cervical cancer. These strains might also contribute to cancers of the
genitals, anus, mouth and upper respiratory tract
- HPV is also responsible for up to 70% of oropharyngeal cancers in the US, wh ich includes all
cancers of the oral cavity and oropharynx
Clinical Manifestations
o Genital warts
appear as flat lesions, small cauliflower-like bumps or tiny stemlike protrusions.
In women, genital warts appear mostly on the vulva but can also occur near the anus, on the
cervix or in the vagina.
In men, genital warts appear on the penis and scrotum or around the anus. Genital warts rarely
cause discomfort or pain, though they may itch or feel tender.
o Common warts- appear as rough, raised bumps and usually occur on the hands and fingers; they can
also be painful or susceptible to injury or bleeding.
o Plantar warts-are hard, grainy growths that usually appear on the heels or balls of feet
o Flat warts- are flat-topped, slightly raised lesions. They can appear anywhere, but children usually get
them on the face and men tend to get them in the beard area. Women tend to get them on the legs.
o Condylomata are rarely premalignant but are an outward manifestation of the virus
Medical Management
No cure for the virus; the goal of management is to relieve symptoms by removing any visible warts and
abnormal cells in the cervix
Cryosurgery: Freezing the warts off with liquid nitrogen.
Loop electrosurgical excision procedure (LEEP): Using a special wire loop to remove the abnormal cells.
Electrocautery: Burning the warts off with an electrical current.
Laser therapy: Using an intense light to destroy the warts and any abnormal cells.
Prescription cream: Topical agents that can be applied by patients to external lesions which include
podofilox (Condylox) and imiquimod (Aldara)- not be used during pregnancy
9-valent HPV vaccine (Gardasil 9 [9vHPV])
88% effective in preventing the combined endpoint of persistent infection, genital warts, vulvar
and vaginal precancerous lesions, cervical precancerous lesions, and cervical cancer related to
HPV types
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Initially approved in 2014, is the only available vaccine in the United States shown to decrease the
risk of certain cancers and precancerous lesions in males and females aged 9-45 years
Children and adolescents aged 15 years and younger need two-rather than the previously
recommended three doses. The second dose should be given 6-12 months after the first dose.
The schedule for older adolescents and young adults aged 15-45 years is 2-3 inoculations
(depending on immunization history) within 6 months
is contraindicated for use in women who are pregnant
Nursing Management
If the treatment includes application of a topical agent by the patient, the patient needs to be carefully
instructed in the use of the agent prescribed and must be able to identify the warts and be able to apply
the medication to them
The patient is instructed to anticipate mild pain or local irritation with the use of these agents.
For plantar warts, advise patient to wear shoes or sandals in public pools and locker rooms
Healthcare professionals must remain alert to any preadolescent child who presents with
anogenital warts, as this may indicate sexual abuse. While the presence of anogenital warts is
not diagnostic for sexual abuse, it is suspicious and warrants further evaluation by a healthcare
provider
Sexual partner counseling can decrease anxiety for the patient and their partner, and offer
opportunities for questions and education on the risk, potent ial infection, and counseling on
prevention.
- HIV is the human immuno deficiency virus. Untreated HIV infects and kills CD4 cells.
- If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome)
- HIV infection in humans came from a type of chimpanzee in Central Africa.
- Two HIV strains have been identified: HIV-1 and HIV-2. HIV-1 is the prototype virus and is responsible
for most cases of AIDS in the United States. HIV-2 is found chiefly in West Africa, appears to be less easily
transmitted, and has a longer incubation period
- The median incubation period is 10 years
- Risks Associated with HIV Infection:
o Sharing infected injection drug use equipment
o Having sexual relations with infected individuals (both male and female)
o Infants born to mothers with HIV infection and/or who are breast-fedby HIV-infected mothers
o People who received organ transplants, HIV-infected blood, or blood products
A. Epidemiology
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B. HIV Transmission
- Higher amounts of HIV and infected cells in the body fluid are associated with the probability that the
exposure will result in infection
- Human immune deficiency virus type 1 (HIV-1) is transmitted in body fluids (blood, seminal fluid, vaginal
secretions, amniotic fluid, and breast milk) that contain infected cells through:
o sexual contact
o the use of needles contaminated by an HIV-infected person
o by blood or other HIV-infected fluids coming in contact with open lesions or mucous membranes
o Deep, open-mouth kissing if both partners have sores or bleeding gums and blood from the HIV-positive
partner gets into the bloodstream of the HIV-negative partner. HIV is not spread through saliva.
o Mother-to-child transmission of HIV-1 may occur in utero, at the time of delivery, or through breast-
feeding, but most perinatal infections are thought to occur after exposure during delivery.
o HIV is not transmitted through casual contact
o Blood and blood products can transmit HIV to recipients (generally blood products given between 1977
and 1985). However, the risk associated with transfusions has been virtually eliminated as a result of
voluntary self-deferral, completion of a detailed health history, extensive testing, heat treatment of
clotting factor concentrates, and more effective virus inactivation methods. Donated blood is tested for
antibodies to HIV-1 and human immunodeficiency virus type 2
C. Prevention
HEALTH PROMOTION:
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ART, antiretroviral therapy; PrEP, pre-exposure prophylaxis.
Total abstinence from addictive drugs might not be a realistic short-term goal.
Other safe and effective woman-controlled methods such as microbicides remain elusive although
clinical trials continue globally. Microbicides are gels, films, or suppositories that can kill or neutralize
viruses and bacteria; vaginal and rectal microbicides are being researched to see if they can prevent
sexual transmission of HIV.
Using a HARM REDUCTION FRAMEWORK:
is an evidence-based, client-centered approach that seeks to reduce the health and social harms
associated with addiction and substance use, without necessarily requiring people who use
substances from abstaining or stopping
acknowledges that many individuals coping with addiction and problematic substance use may
not be in a position to remain abstinent from their substance of choice
those who engage in harm reduction services are more likely to engage in ongoing treatment as
a result of accessing these services
Needle Exchange Programs- a type of harm reduction framework that helps protect individuals
from blood-borne infections like HIV, AIDS and hepatitis by getting used syringes off the streets,
thus reducing the potential for drug users to share a contaminated needle. These programs allow
a person who injects drugs to bring back his or her used needle and/or syringe and receive free,
sterile replacements. Because the exchange is made in person, it offers health care workers an
opportunity to engage people who inject drugs in counseling for health, HIV prevention and
treatment referral
Initial management steps for healthcare personnel exposed to HIV include the following:
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Immediate decontamination
o For percutaneous or cutaneous exposure, washing of the area with soap and water;
o for mucous membrane exposure or eye exposures, copious irrigation of the area with water or
sterile saline;
o for puncture wounds, cleanse with alcohol-based hand wipes
Initiation of institutional PEP plan - Reporting of exposure; confirmation of medication availability;
provision of the initial supply; authorizing release of the drugs; determination of how the healthcare
worker will obtain the medications to complete the 28-day regimen
Ordering of blood tests, immediate treatment, and follow-up within 72 hours, at which time further
review and evaluation can be carried out
Source of exposure - Voluntary testing for HIV, hepatitis C virus antibody, and hepatitis B surface antigen
(HBsAg); if HIV test is positive, confirmatory HIV 1/2 Ab differentiation immunoassay; if HIV infection is
known to be present, obtain relevant information about disease stage
Healthcare worker - Testing for HIV, HCV antibody, HBsAg, and hepatitis B surface antibody (HBsAb); in
females of child-bearing age, pregnancy testing; if HIV PEP is initiated, baseline complete blood (CBC)
count, renal and hepatic function
When indicated, PEP should be initiated as soon as possible The approach to PEP depends on the type
of exposure, the source, and the HIV status of the source.
Post-exposure prophylaxis (PEP)
includes taking antiretroviral medicines as soon as possible, but no more than 72 hours (3 days)
after possible HIV exposure
the sooner the better; every hour counts after a possible exposure to HIV to prevent the virus
from taking hold in your body
Health care workers who are exposed to a needle stick involving HIV infected blood in a health
care setting have a 0.23% risk of becoming HIV infected
Other applicable situations: Think you may have been exposed to HIV during sex (for example,
had a condom break), Shared needles or works to prepare drugs, Were sexually assaulted
It is not a substitute for regular use of other proven HIV prevention methods, such as pre-
exposure prophylaxis (PrEP)
PEP is a combination of three drugs taken once or twice a day for 28 days:
o For adults, the CDC recommends tenofovir, emtricitabine (these two drugs come in one pill), and a
third drug, either raltegravir or dolutegravir.
o Women who are in early pregnancy, who are sexually active and could become pregnant while
taking PEP, or who were sexually assaulted without birth control should take raltegravir rather than
dolutegravir because of a risk of birth defects.
Follow-up HIV antibody testing
Rechecking of CBC, renal function, and hepatic function at 2 weeks
E. Pathophysiology
HIV:
HIV targets and infects a particular type of T-cell called CD4 ‘helper’ cells. These are so called because
they do not kill or neutralize foreign antigens but, instead, signal to and recruit other immune cells to do
so.
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After entering a host’s body, HIV rapidly seeks out the CD4 cells and infects them.
The virus commandeers the function of the CD4 cells, turning them into factories that produce multiple
new copies of the virus; between 10 million and 10 billion new virus cells can be produced daily.
Once infected, CD4 cells develop a much shorter lifespan and are eventually destroyed; their
progressively declining number in the host causes immunological failure and susceptibility to infection.
Oropharyngeal candidiasis
- Is a fungal infection characterized by painless, creamy white, plaque-like lesions that can occur on the
buccal surface, hard or soft palate, oropharyngeal mucosa, or tongue surface
Kaposi Sarcoma
- is a type of cancer that forms in the lining of blood and lymph vessels.
- The tumors (lesions) of Kaposi's sarcoma typically appear as painless purplish spots on the legs, feet or
face. Lesions can also appear in the genital area, mouth or lymph nodes
- In severe Kaposi's sarcoma, lesions may develop in the digestive tract and lungs
- Involvement of internal organs may eventually lead to organ failure, hemorrhage, infection, and death.
Peripheral Neuropathy
- can by caused by the virus itself, by certain drugs used in the treatment of HIV/AIDS or other
complications, or as a result of opportunistic infections like cytomegalovirus [CMV], candidiasis
[thrush], herpes, tuberculosis
- symptoms patients usually experience include burning, stiffness, prickling, tingling, and numbness or a
loss of feeling in the toes and soles of the feet. Sometimes the nerves in the fingers, hands, and wrists
are also affected
HIV encephalopathy
- was formerly referred to as AIDS dementia complex
- HIV causing the brain to swell
- HIV has been found in the brain and cerebrospinal fluid (CSF)
- Early manifestations include memory deficits, headache, difficulty concentrating, progressive confusion,
psychomotor slowing, apathy, and ataxia
- Later stages include global cognitive impairments, delay in verbal responses, a vacant stare, psychosis,
hallucinations, tremor, incontinence, seizures, mutism, and death.
Depressive Manifestations
- Estimates suggest that the prevalence of current depression is between 30% and 40% in persons with
HIV/AIDS.
- Similarly, apathy, which refers to reduced, self-initiated, cognitive, emotional, and behavioral activity, is
also commonly reported among those living with a diagnosis of HIV with rates as high as 65%
G. Diagnostic Findings
- HIV can be diagnosed through blood or saliva testing.
- Blood tests can detect HIV infection sooner after exposure than oral fluid tests because the level of
antibody in blood is higher than it is in oral fluid. Likewise, antigen/antibody and RNA tests detect
infection in blood before antibody tests.
- The CDC recommends at least one HIV test for everyone ages 13 to 64 years. Yearly testing is
recommended if you are at higher risk of infection. The CDC recommends that sexually active gay and
bisexual men consider testing every three to six months
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If a patient receives a diagnosis of HIV/AIDS, several tests can determine the stage of your disease and
the best treatment, including:
CD4 T cell count-CD4 T cells are white blood cells that are specifically targeted and destroyed by HIV.
Even if the patient has no symptoms, HIV infection progresses to AIDS when the CD4 T cell count dips
below 200.
Viral load (HIV RNA)- This test measures the amount of virus in the blood. After starting HIV treatment,
the goal is to have an undetectable viral load. This significantly reduces your chances of opportunistic
infection and other HIV-related complications.
Drug resistance. Some strains of HIV are resistant to medications. This test helps determine if the
specific form of the virus has resistance and guides treatment decisions.
H. Medical Management
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Entry inhibitors
o prevent the virus from entering the targeted cells.
o To penetrate immune cells, HIV must fuse to the cells’ receptors, and these drugs work to stop
this from happening.
o Examples: enfuvirtide (Fuzeon)
Integrase inhibitors
o HIV uses a protein called integrase to send its genetic material into the cells that it targets.
Integrase inhibitors block this action.
o Examples: dolutegravir (Tivicay)
Other management:
Treatment of opportunistic infections. For Pneumocystis pneumonia, trimethoprim–sulfamethoxazole
(TMP-SMP)is the treatment of choice
Antidiarrheal therapy. Therapy with octreotide acetate (Sandostatin), a synthetic analog of
somatostatin, has been shown to be effective in managing severe chronic diarrhea.
Antidepressant therapy. involves cognitive behavioral therapy integrated with pharmacotherapy.
Nutrition therapy. For all AIDS patients who experience unexplained weight loss, calorie counts should
be obtained, and appetite stimulants and oral supplements are also appropriate.
Alternative medicine
- many may interfere with other medications being taken
- Supplements that may be helpful
o Acetyl-L-carnitine. It may also ease neuropathy linked to HIV if the patient is lacking in the substance.
o Whey protein and certain amino acids. Early evidence suggests that whey protein, a cheese byproduct,
can help some people with HIV gain weight. Whey protein also appears to reduce diarrhea and increase
CD4 T cell counts. The amino acids L-glutamine, L-arginine and hydroxymethylbutyrate (HMB) may also
help with weight gain.
o Probiotics. There is some evidence that the probiotic Saccharomyces boulardii may help with HIV-
related diarrhea, but use only as directed by the doctor
o Vitamins and minerals
- Supplements that may be dangerous:
o St. John's wort. A common depression remedy, St. John's wort can reduce the effectiveness of several
types of anti-HIV drugs by more than half.
o Garlic supplements. Although garlic itself may help strengthen the immune system, garlic supplements
may interact with some anti-HIV drugs and reduce their ability to work. Occasionally eating garlic in food
appears to be safe.
o Red yeast rice extract. Some people use this to lower cholesterol, but it must be avoided if taking a
protease inhibitor or a statin.
J. Nursing Management
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anticholinergic agents, antispasmodic agents, or opioids, can be prescribed to decrease diarrhea by
reducing intestinal spasms and motility.
PREVENTING INFECTION
monitor for signs and symptoms of infection
The nurse also monitors laboratory test results that indicate infection
IMPROVING ACTIVITY TOLERANCE
Assistance in planning daily routines that maintain a balance between activity and rest may be necessary.
energy conservation techniques, such as sitting while washing or preparing meals.
Personal items that are frequently used should be kept within the patient’s reach.
relaxation and guided imagery may be beneficial
MAINTAINING COHERENT THOUGHT PROCESSES
The patient is assessed for alterations in mental status
Reorientation to surroundings and location is conducted as needed.
Activities that the patient previously enjoyed are encouraged.
IMPROVING AIRWAY CLEARANCE
Respiratory status, as well as mental status and skin color, must be assessed
Pulmonary therapy (coughing, deep breathing, postural drainage, percussion, and vibration) is provided
as often as every 2 hours to prevent stasis of secretions and to promote airway clearance.
Adequate rest is essential to minimize energy expenditure and prevent excessive fatigue
Humidified oxygen may be prescribed, and nasopharyngeal or tracheal suctioning, intubation, and
mechanical
ventilation may be necessary to maintain adequate ventilation.
RELIEVING PAIN AND DISCOMFORT
The patient is assessed for the quality and severity of pain associated with impaired perianal skin
integrity, the lesions of KS, and peripheral neuropathy.
Antispasmodic and antidiarrheal medications may be prescribed to reduce the discomfort and frequency
of bowel movements.
Pain management may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids
plus nonpharmacologic approaches
IMPROVING NUTRITIONAL STATUS
Nutritional status is assessed by monitoring weight; dietary intake; and serum albumin, BUN, protein,
and transferrin levels.
implement specific measures to facilitate oral intake.
The dietitian is consulted to determine the patient’s nutritional requirements.
The patient is encouraged to eat foods that are easy to swallow and to avoid spicy or sticky food items
and foods that are excessively hot or cold.
Patients who cannot maintain their nutritional status through oral intake may require enteral feedings
or parenteral nutrition.
DECREASING THE SENSE OF ISOLATION
People with AIDS are at risk for double stigmatization
People with HIV infection may be overwhelmed with emotions such as anxiety, guilt, shame, and fear.
Nurses are in a key position to provide an atmosphere of acceptance and understanding for people with
AIDS and their social networks.
IMPROVING KNOWLEDGE OF HIV
The patient and family are educated about HIV infection
The patient is instructed to avoid others with active infections, such as upper respiratory infections
Condom Do’s
use a condom every time you have sex.
put on a condom before having sex.
read the package and check the expiration date.
make sure there are no tears or defects.
store condoms in a cool, dry place.
use latex or polyurethane condoms.
use water-based or silicone-based lubricant to prevent breakage.
Condom Don’ts
store condoms in your wallet as heat and friction can damage them.
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use nonoxynol-9 (a spermicide), as this can cause irritation.
use oil-based products like baby oil, lotion, petroleum jelly, or cooking oil because they will cause the
condom to break.
use more than one condom at a time.
reuse a condom.
REPUBLIC ACT No. 11166 :Philippine HIV and AIDS Policy Act
- Approved: December 20, 2018
SCREENING, TESTING AND COUNSELING
- In every circumstance, proper counseling shall be conducted by a social worker, a health care provider,
or other health care professional accredited by the DOH or the DSWD
Section 30. Compulsory HIV testing shall be allowed only in the following instances:
When it is necessary to test a person who is charged with serious and slight physical injuries, and on rape
and simple seduction
When it is necessary to resolve relevant issues under "The Family Code of the Philippines"
As a prerequisite in the donation of blood
Section 32. HIV Testing for Pregnant Women- A health care provider who offers pre-natal medical care
shall offer provider-initiated HIV testing for pregnant women.
CONFIDENTIALITY
Section 44. Confidentiality
- The confidentiality and privacy of any individual who has been tested for HIV, has been exposed to HIV,
has HIV infection or HIV- and AIDS-related illnesses, or was treated for HIV-related illnesses shall be
guaranteed.
Violations:
Disclosure of Confidential HIV ad AIDS Information. - Unless otherwise provided, it shall be unlawful to
disclose, without written consent, information that a person has AIDS, has undergone HIV-related test,
has HIV infection or HIV-related illnesses, or has been exposed to HIV.
Penalty: Six months to two years of imprisonment for any person who breaches confidentiality, and/or a
fine of P50,000.00 to P150,000.00
Media Disclosure. - It shall be unlawful for any editor, publisher, reporter or columnist, or any announcer
or producer or any other individual or organization in case of social media, to disclose the name, picture,
or any information that would reasonably identify persons living with HIV and AIDS, or any confidential
HIV and AIDS information, without the prior written consent of their subjects except when the persons
waive said confidentiality through their own acts and omissions
Penalty: Two years and one (1) day to five (5) years of imprisonment for any person who causes the mass
dissemination of the HIV status of a person, and/or a fine of P150,000.00 to P350,000.00
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Confidentiality shall likewise be observed
Further the DOH shall establish an enabling environment to encourage newly tested HIV positive
individuals to disclose their status to partners.
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