Antifungals

Cell wall – echinocandins

Cell membrane – polyenes – Amp B, Nystatin
Inhibit ergosterol – Azoles

Antibiotics – Bugs very mad cos antibiotics taken queen marg, too
Cell wall – beta lactams, vancomycin
Inhibit protein synthesis
- 50s – macrolides (azithromycin, erythromycin), clindamycin
- 30s – aminoglycosides (gentamicin), tetracyclines (doxycycline)
Inhibit DNA – quinolones (ciprofloxacin), metronidazole
Inhibit Folate – Trimethoprim

Immunosuppresants – stop creating the autoimmune man

Inhibit IL-2 action – Sirolimus
Inhibit IL-2 production – Ciclosporin, tacrolimus
Inhibit Purine synth – Azathioprine, Mycophenolate

Renal cysts – Bosniak Class

1 – simple cysts // 2 – thin septa // 2F – increased septa // 3- thick septa // 4- solid mass

DTPA and MAG3 (preferred in neonates, impaired function) – renal function tests

Glucocorticoids INCREASE bone resorption

MCV = HC x 1000/RBC
MCHC = Hb/HC

Urinary clearance = Urine concentration x urine production / plasma concentration

Suxamethonium broken down by plasma cholinesterase (non-depolarising agents broken

down by neostigmine)

Lung volumes – 6 LITER

Lung Capacity 6L = IRV 3.3L, TV 0.5L, ERV 1L, RV 1.2L
IC = TV + IRV
VC = TV+ IRV + ERV
FRC = ERV + RV