A. Hba and HBF Are Usually Normal or Decreased

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1.

Regarding fetal Hb (HbF) which of the following is the CORRECT statement:


a. It is about 10% at birth
b. It consists of 2  and 2  globin chains
c. It has poor affinity to O2
d. High level of HbF minimize sickle cell crisis
e. Genes coded for its globin chains are located on chromosom19 &22
2. In Iron deficiency anemia (IDA): which is the CORRECT statement:
a. HbA2 and HbF are usually normal or decreased
b. RDW (red distribution width) is usually normal or decreased
c. Platelets and WBC counts characteristically are decreased
d. Serum iron and TBIC are the gold standard test to confirm IDA
e. It is the common cause of anemia in a full term infant at age of 2
months
3. The following are correct statements regarding neutropenia EXCEPT:
a. In children is defined by absolute count less than 1500 mm 3
b. It is usually presented with fever sore throat fever and mouth ulcer
c. G-CSF (granulocyte colony stimulating factor) has important role in
increasing the count
d. Ampicillin is the drug of choice as empiric treatment in febrile
neutropenia
e. Cyclophosphamide is a recognized cause
4. 2 day old jaundiced newborn with Hb of 10gm/dl, reticulocyte 10% normal
WBC and plat, the most likely diagnosis is:
a. Sickle cell anemia
b.  thalassemia major
c. G6PD deficiency
d. Maternal systemic lupus erythromatosus (SLE)
e. HbC hemoglobinopathy
5. Which of the following is a recognized cause of thrombocytopenia
a. Kawasaki disease
b. Ulcerative colitis
c. Aspirin
d. Splenomeglay
e. Hepatomeglay

6. 5 year old boy with recurrent knee joint swellings which of the following is the
most helpful in the diagnosis:
a. Plat of 50,000 mm3
b. ASO of 1000 unit
c. Activated partial thromboplastin time (aPTT) of 180 seconds
d. Both sister and brother have the same disease
e. Purpurae on legs and buttocks

7. A well looking child with recurrent epistaxis & bleeding gums, normal
activated partial thromboplastin time (aPTT), normal Prothrombin time (PT),
and normal Plat count, most likely has:
a. Warfarin overdosing
b. Thromasthenia
c. Henoch Shoenlein purpura
d. Factor XII deficiency
e. DIC

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