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Blood Transfusion Part 3
Blood Transfusion Part 3
Whole blood: When having acute massive blood loss of greater than 1000ml, requiring the
oxygen carrying properties of RBCs and the volume expansion provided by plasma. It should be
transfused within 2-4 hours.
Packed Red Blood Cells: Restoration or maintenance of adequate organ oxygenation with
minimal expansion of blood volume. It should be transfused within 2-4 hours for adult and 2 to 5
ml/kg per hour for pediatric.
Platelet concentrates: Prevention or resolution of hemorrhage in patients with thrombocytopenia
or platelet dysfunction. It should be transfused within 30-60 minute.
Fresh frozen plasma (FFP): Treatment of blood loss or blood clotting disorders related to liver
disease and failure, Disseminated intravascular coagulation (DIC) and Over-anticoagulation with
warfarin. It should be transfused within 15- 30 minutes.
Cryoprecipitate: Correction of deficiencies of factor VIII and bleeding due to hemophilia or
DIC. It can be completed within 3 to 15 minutes.
Granulocyte: Treatment of life-threatening bacteria or fungal infection unresponsive to other
therapy in patient with severe neutropenia. It should be transfused within 30 minutes.