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Diagnosis and Management of Gastroesophageal Reflux in Preterm Infants
Diagnosis and Management of Gastroesophageal Reflux in Preterm Infants
and feeding regimen manipulation, have not been shown to reduce clinically This document is copyrighted and is property of the American
Academy of Pediatrics and its Board of Directors. All authors have
assessed signs of GER in the preterm infant. In addition, preterm infants filed conflict of interest statements with the American Academy
with clinically diagnosed GER are often treated with pharmacologic agents; of Pediatrics. Any conflicts have been resolved through a process
approved by the Board of Directors. The American Academy of
however, a lack of evidence of efficacy together with emerging evidence of Pediatrics has neither solicited nor accepted any commercial
involvement in the development of the content of this publication.
significant harm (particularly with gastric acid blockade) strongly suggest
that these agents should be used sparingly, if at all, in preterm infants. Clinical reports from the American Academy of Pediatrics benefit from
expertise and resources of liaisons and internal (AAP) and external
reviewers. However, clinical reports from the American Academy of
Pediatrics may not reflect the views of the liaisons or the organizations
or government agencies that they represent.
of acidity) and quantity of reflux3,4 as well as potential injury to the FINANCIAL DISCLOSURE: The author has indicated he has no financial
relationships relevant to this article to disclose.
esophageal mucosa. GER is a common diagnosis in the NICU; however,
there is as much as a 13-fold variation in its diagnosis and treatment
across sites.5,6 Preterm infants who are diagnosed with GER have longer To cite: Eichenwald EC and AAP COMMITTEE ON FETUS AND
NEWBORN. Diagnosis and Management of Gastroesophageal
hospital stays and higher hospital costs than infants without GER,5,7, 8
Reflux in Preterm Infants. Pediatrics. 2018;142(1):e20181061
making it an important clinical phenomenon in the NICU.
POTENTIAL CONFLICT OF INTEREST: The author has indicated he has no potential conflicts of interest to disclose.
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References This article cites 70 articles, 23 of which you can access for free at:
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