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Infection: Medicine Update 2017 - Volume 2
Infection: Medicine Update 2017 - Volume 2
Infection: Medicine Update 2017 - Volume 2
CONTENTS
Medicine uPdate 2017 • VoluMe 2
SECtION 1
Infection
1. Basics of Prescribing Antimicrobial Drugs
Mahadev T Desai 3
2. rational for Antibiotics – Guidelines
Mangesh Tiwaskar, Tanuja Manohar 6
3. Pyrexia of Unknown Origin - Physician’s Challenge
Asha N Shah 16
4. Vector Borne Diseases
Falguni S Parikh 20
5. Tropical Fevers
Smarajit Banik, Sabyasachi Mukhopadhyay 23
6. Diagnostic Challenges of Malaria in India
Sarita Behera 28
7. Changing Profile of Dengue Infection in India
Prasanta Kumar Bhattacharya, Aakash Roy 32
8. Dengue Profile in Guwahati
PC Bhattacharyya, Manabendra Nayak, Lalit Mohan Bhardwaj 35
9. Leptospirosis in Current Status
Shobha Manish Itolikar 39
10. Management of Kala-Azar – from Bench to Bedside
Shyam Sundar, Jaya Chakravarty 42
11. Viral Hemorrhagic Fever
Debasis Chakrabarti 45
xl 12. Swine Flu
Bala Vinoth, D Suresh Kumar 50
13. Clinical Presentation and Systemic Manifestations of Zika Virus
Rajib Ratan Chaudhary 54
14. Typhoid Fever: An Index of Sanitation in India
K Nagesh 59
15. Typhoid Fever – Recent Management
Uttam Kumar Paul 64
16. Atypical Presentation of Typhoid Fever: A Case Report
CONTENTS
SECtION 2
Tuberculosis
21. Available Diagnostic Tools in Mycobacteriology: A recap on Utility
Mohanjeet Kaur, Ashish Chawla 91
22. Molecular Diagnosis of Tuberculosis
Supriya Sarkar 98
23. Challenges in the Diagnosis of Extrapulmonary Tuberculosis
Bidita Khandelwal 102
24. Approach to Neurotuberculosis
Virendra Kr Goyal 105
25. Indian Scenario Management of Tuberculosis
Vishal Chopra, Jawahar Lal Joshi, Ashrafjit S Chahal 110
26. Drug Resistant Tuberculosis
Pralhad P Prabhudesai, Abha Pandey 114
xli
SECtION 3
HIV
27. HIV Epidemiology
BB Rewari 123
28. HIV & Diabetes – A Double Trouble
PK Agrawal 128
CONTENTS
29. Bone Health in HIV
AR Pazare 132
30. Opportunistic Infections in HIV
Partha S Karmakar, Tuhin Santra, Apu Adhikary 134
31. Management of Failure of Antiretroviral Treatment
Subhasish Kamal Guha, Dolanchampa Modak 139
SECtION 4
Immunology
32. ‘Hygiene Hypothesis’ and Development of Immunity
Bidyut Kumar Das, Aditya K Panda 145
33. Adult Immunization
OP Sharma 148
34. Monoclonal Antibodies: what Clinicians Should Know
Anand Sudhakar Bhave 152
SECtION 5
Rheumatology
35. Approach to Arthritis
Liyakat Ali Gauri, BR Ajay, Asim Khan, Nadeem Liyakat, Qadir Fatima 157
36. Approach to Seronegative Arthritis
Harminder Singh Pannu, Harpreet Kaur, Anmol Singh, Piyush Harchand 166
37. Pre-clinical rheumatoid Arthritis - Identification and Implication
Rohini Handa 171
xlii 38. remission in rheumatoid Arthritis: A reality in 2017
Shankar Subramanian 175
39. Gout in 2017
Arup Kumar Kundu, Abhishek Kundu 179
40. The Future of Systemic Lupus Erythematosus
Satyabrata Ganguly, Anish Kar 183
41. Pulmonary renal Syndrome
Yojana Gokhale, Raosaheb Rathod 186
42. Antiphospholipid Syndrome
CONTENTS
SECtION 6
Pulmonology
43. Chronic Cough - Diagnostic Dilema
M Sabir, Sanjay Kochar, Sanjay Tundwal 197
44. Non resolving Pneumonia
Devendra Prasad Singh 201
45. Health Care Associated Pneumonias
Atul Bhasin, RK Singal 205
46. How to Manage Solitary Pulmonary Nodule (SPN)
Keerat Kaur Sibia, Rajbir Singh, Akash Batta, Rishu Bhanot, RS Bhatia, SS Sibia 207
47. Chronic Granulomatous Disorders: what we Know
Dinesh Gupta, GursimranKaur 213
48. Current Concepts and Controversies in the Treatment of Pulmonary Sarcoidosis
Akashdeep Singh 216
49. Approach to Difficult Asthma
Amita Nene 219
50. Newer Therapies in COPD
Prem Parkash Gupta 222
51. Interstitial Lung Diseases
Ketaki Barve, Jyotsna M Joshi 228
52. Fungal Infection in the Lung
Udas Chandra Ghosh, Kaushik Hazra 232
53. Tropical Pulmonary Eosinophilia
Harpreet Singh 236
54. Role of Bronchoscopy in Diffuse Parenchymal Lung Diseases
Ajay Handa, Jyothi Ranganathan 238
55. Role of Interventions in Pulmonology xliii
Agam Vora 244
56. High Altitude and Respiratory System
BNBM Prasad 256
57. Acute Mountain Sickness
Rajiv Raina, Sanjay K Mahajan 267
58. Pulmonary Hypertension - Hope & Challenges
Sudhir Varma, Samman Verma 273
CONTENTS
SECtION 7
Gastroenterology
59. Long Term PPI Use: Is it Really Safe?
Ramesh Roop Rai 279
60. PPIs and Antiplatelets Latest Concepts
Randhir Sud 282
61. Management if Irritable Bowel Syndrome: A Practical Approach
Uday C Ghoshal 285
62. Making a Positive Diagnosis of Irritable Bowel Syndrome
Ujjwal Sonika, Vineet Ahuja 292
63. Chronic Diarhoea – An Approach
Swaroop Kumar Baruah, Suman Talukdar 295
64. Management of Ulcerative Colitis: Step-up or Step-down Approach?
Bhaskar Nandi 300
65. Medical Management of Acute Pancreatitis
Rajoo Singh Chhina, Amit Bansal, Amanat Sidhu, Rajdeep Singh 306
SECtION 8
Hepatology
66. NAFLD and Diabetes
Lalit Kumar Meher, Sunil Kumar Kota 311
67. Diabetic Hepatopathy
Rajesh Upadhyay 314
68. NAFLD – Where Do We Stand Today
KK Lohani 319
xliv 69. NASH: Do we really have an Effective Treatment?
Sandeep Satsangi, Ajay Duseja 322
70. Alcoholic Hepatitis in India: Current Prospective and Management
Suresh Kumar 326
71. Ascites - From Basics to Bedside
Harbir Kaur Rao, Rajinder Singh Gupta 329
72. Approach to Hepatorenal Syndrome
DN Amarapurkar 334
73. Should we Treat Chronic Hepatitis B Carrier
CONTENTS
SECtION 9
Geriatrics
76. Telomere and Ageing
VN Mishra, Nalini Mishra, Ishan 353
77. The Immunity in Elderly
Jyotirmoy Pal, Pradip Kumar Chowdhury 356
78. Atrial Fibrillation in Elderly
Vijay Garg, Raman Parashar, Aadish Kumar Jain, AK Pancholia 362
79. Infections in Elderly
Gandharba Ray, L Ravi Kumar 368
SECtION 10
Neurology
80. Primary Headache Disorders - An Update
Anup Kr Bhattacharya, Agnibha Maity 375
81. Approach to Hyperkinetic Movement Disorders
Balamurugan Namasivayam 384
82. Management Tips of Epilepsy: A Physician’s Perspective
Sudhir V Shah 388
83. Management of Epilepsy in Special Situations xlv
Jaslovleen Kaur, Gagandeep Singh 391
84. recent Advances in Epilepsy
Sushil Tandel 394
85. Surgery for Parkinson’s disease and Epilepsy
Paresh Doshi, Raghvendra Ramdasi, Smita Thorve 398
86. Thrombolysis in Stroke - Experience In India
Apratim Chatterjee, Subhodeep Gupta, Bhaskar Ghosh, Biman Kanti Ray 407
87. Tough Calls in Neurology
CONTENTS
K Mugundhan 412
88. Motor Neuron Diseases
Joy D Desai 418
89. A Case Based Approach to Acute Flaccid Paralysis
Salil Gupta 423
90. Approach Towards a Patient with Vertigo
Sanjiv Maheshwari, Ravi Kumar Meena 427
SECtION 11
Haematology
91. Iron Deficiency Anemia – Needs Attention and Proper Management
Pramod Kumar Sinha 435
92. Iron Deficiency in Heart Failure
K Sarat Chandra 439
93. Anaemia of Chronic Disease: Current Update
Ananda Bagchi, Aradhya Sekhar Bagchi 441
94. Clinical Utility of Erythrocyte Sedimentation rate in Modern Era
Pratap Singh, Sanjay Kumar 447
95. Pancytopenia: Clinical approach
Ajai Kumar Garg, AK Agarwal, GD Sharma 450
96. Current Management of Hemophilia
S Usha 455
97. Hemophilia: Prophylactic Therapy with Conventional and Newer Agents
Tarun Kumar Dutta, Shailendra Prasad Verma, Deepak Charles 463
98. Newer Therapies in Hemophilia
Sandeep Garg, Naresh Gupta, Sunita Aggarwal 466
99. Artificial Blood: An Update on Current red Cell and Platelet Substitutes
AS Mohan 469
xlvi 100. Blood Component Therapy
Mathew Thomas 473
101. Chronic Myeloid Leukaemia – An Overview
Sunita Aggarwal, Jahnvi Dhar, Sandeep Garg, Naresh Gupta 478
SECtION 12
Pregnancy
CONTENTS
SECtION 13
Poisoning
112. Approach to the Patient with Unknown Poisoning
Biranchi Narayan Mohapatra, CBK Mohanty 529
113. Management of Snake Bite in India
Shibendu Ghosh, Prabuddha Mukhopadhyay 532
114. Mushroom Poisoning xlvii
Bhupen Barman, KG Lynrah, Iadarilang Tiewsoh 538
115. Approach to Common Poisoning in Punjab
Gursaran Kaur Sidhu 542
116. Therapeutic Plasma Exchange and Continuous Renal Replacement Therapy as Rescue Therapy in
Paracetamol Induced Fulminant Hepatic Failure
Rajesh Mishra 547
SECtION 14
CONTENTS
Critical Care
117. ABG Analysis in Clinical Setting
Rajesh Mahajan, Suman Sethi 553
118. Electrolytes in ICU
TH Trivedi 558
119. Glycemic Control in I.C.U.
Ramesh Kumar Goenka 562
120. Approach to Sepsis
Gurinder Mohan, AP Singh, Ranjeet Kaur 568
121. Sepsis - Old wine in New Bottle?
Puneet Saxena, Madabhushi Shyam 572
122. Septic Shock: How Do I Manage?
Pravat Kumar Thatoi 576
123. AKI in ICU – Diagnosis and Management
Georgi Abraham, Neethu Venkitakrishnan 578
SECtION 15
Nephrology
124. Microalbumunuria - A risk Factor for CVD
Mritunjay Kumar Singh 587
125. Management of Anemia in Chronic Kidney Disease: Revisited
Narinder Pal Singh, Neena Garg 590
126. Kidney Injury in Tropical Infections
HK Aggarwal, Deepak Jain, Pulkit Chhabra 597
127. Contrast Associated Acute Kidney Injury: Nephrologist’s Perspective
Dinesh Khullar 600
xlviii 128. Chronic Kidney Disease of Unknown Etiology
Sudhir Kulkarni, Kshitija Gadekar 603
129. Complicated Urinary Tract Infection
Dipankar Bhowmik, Sudeep Singh 607
130. My Diet Plan for Diabetic and CKD
Sanjay Dash 610
SECtION 16
Hypertension
131. Power to Control Systolic Blood Pressure-An Indian Evidence
Tiny Nair 615
132. High Altitude Systemic Hypertension (HASH) - A New Entity
Yanamandra Uday, Velu Nair 618
133. Alcohol and Hypertension related Left Ventricular Systolic Dysfunction-Intergrated Approach
Using Echocardiography
Maninder Singh, Suraj Kumar Arora, Rohit Tandon 622
134. renovascular Hypertension
R Chandni, R Gayathri 627
135. Resistant Hypertension
Kidiyur Jayakar Shetty, Manohar Kathige Nageshappa 631
136. Vascular Remodeling in Hypertension
Sanjay Jain, Srikanth Gopi 634
137 Secondary Hypertension: An Age-Based Approach to Diagnosis
Amit A Saraf, Anoosha Bhandarkar 637
138. Difficult to Treat Hypertension
RK Singal, Vivek Pal Singh, AK Vardani 640
139. Hypertension Urgencies & Emergencies
Sekhar Chakraborty 643
140. YOUNG Hypertensives: Do we Need to Look at them Differently?
Sanjay Kalra, KVS Hari Kumar 650
141. NCD Update: Connection between Chronic Kidney Disease and Cardiovascular Disease
C Venkata S Ram 653
142. Hypertension in CKD - Management Issues
Pritam Gupta, Ankur Gupta 658
143. Managing Blood Pressure in Acute Stroke : A Dilemma
Bhupendra Chaudhary, Binay Karak 662
144. Impact of recent Hypertension Guidelines on Clinical Practice xlix
NK Soni, VB Jindal 665
145. Best Practices in Hypertension-2017
PC Manoria, Pankaj Manoria, Piyush Manoria, SK Parashar 670
146. Role of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in
Hypertension 2017
Santosh Bandopant Salagre 677
147. Newer Beta Blocker in Hypertension
Anita Jaiswal 680
CONTENTS
148. Hypertension Guidelines for 2017 – The Evidence So Far
Uday M Jadhav, Amit Saraf 682
149. Combination Drug Therapy in Hypertension
AU Mahajan, Zohaib Shaikh 684
150. Recent Advances in Ambulatory Blood Pressure
Ashok L Kirpalani, Dilip A Kirpalani 690
151. A Review of Nutritional Factors in Hypertension Management
Ashok K Taneja, Tejinder Singh, Ashok Chandna 695
152. Life Style Modification in Non Communicable Diseases
BB Thakur, Smita Thakur 701
153. Approach to the Patients with Hypertension
BR Bansode 705
SECtION 17
Metabolism
154. Exploiting the Gut to Treat Obesity
Soumitra Ghosh 713
155. Newer Lipid Guidelines: Interpretation and Applications for Indians
SN Narasingan 720
156. Management of Dyslipidemia in India: What should be Our Approach in View of the Differing
Guidelines
Santanu Guha, Sumanta Chatterjee 726
157. Pharmacotherapy of Obesity
Sachin Kumar Jain, Rati Singh, Ramesh Aggarwal, Ritika Sud 731
l
SECtION 18
Diabetes
158. Unburdening the Burden of Diabetes
V Seshiah, V Balaji, Madhuri S Balaji 739
159. Diabetes: Ethical Issues
Vitull K Gupta, Meghna Gupta, Sonia Arora 742
CONTENTS
CONTENTS
Parikshit Goswami 826
181. Empagliflozin: Potential Mechanisms of Cardiovascular Benefits
Aparna Kansal, Suman Kirti, YP Munjal 830
SECtION 19
Endocrinology
182. Panhypopituitarism
Minal Mohit 837
183. Vitamin D: In Health and Clinical Practice
BK Mahavarkar, Anoosha Bhandarkar 845
184. Subclinical Hypothyroidism
Gayatri Ghanekar, Manoj Chadha 849
185. Subclinical Hyper and Hypo Thyroidism - When to Treat
Ankit Shrivastav 852
186. Hypothyroidism.....Beyond Thyroid !
Alaka Deshpande 856
187. Obesity- Tackling the Epidemic with an Individual-Centric Approach
Anupam Prakash 859
SECtION 20
Venous Disorders
188. Anatomy, Physiology & Classification of Varicose Veins
Ravul Jindal, Bhanupriya Wadhawan, Piyush Chaudhary 867
189. Incidence and Prevalence of Venous Disease in India
Pinjala Ramakrishna 871
lii 190. Medical Treatment of Varicose Veins
Ajay K Khanna, Soumya Khanna 873
191. Endovenous Ablation Therapy for Varicose Veins
Shoaib F Padaria 875
192. Over View of Management of Acute Deep Vein Thrombosis
Vimalin Samuel, Edwin Stephen 876
193. Pulmonary Embolism
Harinder Singh Bedi 879
194. Catheter directed Thrombolysis in Deep Vein Thrombosis ( DVT), Technique and results Over Last
CONTENTS
Decade
DB Dekiwadia 886
SECtION 21
Cardiology
195. Back to Bedside Basics - Pulse, Blood Pressure and Jugular Venous Pulse
Ruchit A Shah, BR Bansode 889
196. Coagulation Cascade - What’s New
BL Bhardwaj, Harnoor S Bhardwaj, Pallav Jain, Kanchan Saini 900
197. Anti-Platelet Therapy
Nihar Mehta, Nikesh Jain 903
198. Combined Oral Anticoagulation and Antiplatelet Therapy - Management of a Difficult Situation
Jamshed J Dalal 910
199. How to Prevent and Control the Epidemic of Coronary Artery Disease in Indians
Julian Johny Thottian, Binjo Vazhappilly, Mohanan Padinharepurayil 912
200. Noninvasive Testing for Diagnosis of Stable Coronary Artery Disease
Srinivasan Narayanan, Ajit Mullasari 915
201. Management Strategies in Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) in India
Satyavan Sharma, Nikhil Raut 919
202. Management of Stable Ischemic Heart Disease – Current Perspective
Dev Pahlajani 923
203. STEMI Care in India and the real world: role of Thrombolysis
HK Chopra 925
204. risk Stratification and Management Algorithm of NSTEMI
Lekha Pathak, Ankur Jhavar 934
205. Cardiac Intervention
Pawan K Suri 943
206. Recent Developments in Intensive Cardiac Care for Acute Cardiac Disorders
Suraj Kumar Arora, Abhishek Goyal, Gurpreet S Wander 946
207. Five recent Land Mark Trials in Cardiology: How have They Changed Our Practice liii
VK Bahl, Anunay Gupta 951
208. To Assess Predictive Value of Carotid Artery Intima Media Thickness as a Non-Invasive Marker for
Coronary and Cerebral Artery Disease
Gurmukh S Sainani, Mitul A Shah 954
209. Two-and Three-Dimensional Echocardiographic Assessment of the Aortic Valve
Efstathia Andrikopoulou, Garima Arora, Navin C Nanda 958
210. Management of Atrial Fibrillation in Indian Scenario
Saumitra Ray, Amitava Mazumdar 963
CONTENTS
211. Heart Failure in Young and Elderly – Management Strategies
Brian Pinto, Chetan Rathi, Ankeet Dedhia 966
212. Cardiac Pacemakers: Indications, Choices and Follow Up
Sandeep Bansal, Praloy Chakraborty 976
213. Sudden Cardiac Death in Young People: Can it be Prevented
Harendra Kumar 980
214. Update in Preoperative Cardiovascular Evaluation and Perioperative Cardiovascular Medical
Management
Michael A Mikhail, Arya B Mohabbat, Amit K Ghosh 983
215. Transcatheter Aortic Valve Implantation (TAVI)
Vivek Gupta, Alain Criber 992
SECtION 22
Beyond Medicine
NETAJI OrATION
216. Physician: The Healer and the Professional
Satish V Khadilkar 1001
217. Medical Practices on Cross roads
DN Upasani 1005
218. Personalized Medicine: Making Effective Therapy Safe for Every Individual
Ramchandra D Lele 1007
219. Doctor-Patient relationship
Ambika Prasad Mohanty 1011
220. Democratizing Knowledge to Improve Care for the Underserved: Project ECHO
Sanjeev Arora, Kumud Rai, Sunil Anand 1014
221. ADVANCE to ADVANCE on: The First Evidence of Legacy Effect in
the Management of Hypertensive Diabetic Patients
Sanjay Kalra 1017
222. Laughter is the Best Medicine
Anil Chaturvedi 1019
223. Medicine is a Serious Business?
Arulrhaj, Aarathy Kannan, Ajinkya Borhade, Sachin Babhalsure 1021
liv 224. Saga of Man, Microbiome and P4 Bedside Medicine
Prakash Pispati 1024
225. Nuclear Medicine as a Problem Solver in Diagnosis and Therapy
Vikram R Lele 1027
226. Does Modern Medicine Increase Life-expectancy: Quest for the Moon Rabbit?
Sundeep Mishra 1032
227. The Heart and Lung cannot Live without Each Other
Bhavin Jankharia 1041
228. New Approach to Management of Erectile Dysfunction in 2017
CONTENTS