Republic of the Philippines Founded 1907 RA 9299

NEGROS ORIENTAL STATE UNIVERSITY

Dumaguete, Bais, Guihulngan, Mabinay, Pamplona, Siaton and Bayawan-Sta. Catalina
COLLEGE OF NURSING, PHARMACY AND ALLIED HEALTH SCIENCES

RELATED
READINGS
 Republic of the Philippines Founded 1907 RA 9299

NEGROS ORIENTAL STATE UNIVERSITY

Dumaguete, Bais, Guihulngan, Mabinay, Pamplona, Siaton and Bayawan-Sta. Catalina
COLLEGE OF NURSING, PHARMACY AND ALLIED HEALTH SCIENCES

Reading #1

Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani

Tetanus toxin synthesis is under the control of a complex network of regulation linked to the metabolism in Clostridium tetani including at least two positive and one
negative two component system regulators and the master regulator of metabolism CodY. Inorganic phosphate and carbonate are environmental factors involved in the control of
tetanus toxin synthesis.
 Republic of the Philippines Founded 1907 RA 9299

NEGROS ORIENTAL STATE UNIVERSITY

Dumaguete, Bais, Guihulngan, Mabinay, Pamplona, Siaton and Bayawan-Sta. Catalina
COLLEGE OF NURSING, PHARMACY AND ALLIED HEALTH SCIENCES

Reading #2

Insufficient knowledge and inappropriate practices of emergency doctors towards

tetanus prevention in trauma patients: a pilot survey

Most emergency doctors’ knowledge and practices strayed from the recommendations of Advisory Committee on Immunization Practices (ACIP):

1) TIG alone for most trauma patients instead of vaccine was an overused treatment approach.
2) Most of the emergency doctors lacked formal training on and knowledge of tetanus vaccination.
3) Even the emergency doctors themselves were not properly vaccinated.
4) The tetanus vaccine was only available in a small number of the respondents’ institutions.