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Major Findings in The Research of New Coronavirus Pneumonia: The Mechanism of Mutual Mutagenesis and Mutation of New Coronavirus Pneumonia Bacteria (Fangruida
Major Findings in The Research of New Coronavirus Pneumonia: The Mechanism of Mutual Mutagenesis and Mutation of New Coronavirus Pneumonia Bacteria (Fangruida
Major Findings in The Research of New Coronavirus Pneumonia: The Mechanism of Mutual Mutagenesis and Mutation of New Coronavirus Pneumonia Bacteria (Fangruida
The mechanism of mutual mutagenesis and mutation of new coronavirus pneumonia bacteria
(Fangruida)
2021 revision 2021v.1.5
Medical scientist virologist Fang Ruida new coronavirus research) Besque compiles 2020v3.1 online
version e-book
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Fang Ruida's major discovery in the research and prevention of new coronavirus pneumonia
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Abstract
The new coronavirus pneumonia has spread globally for more than a year, with more than 2 million
deaths and more than 20 million infections. In addition to the pathological source of the pandemic and
the development of vaccine drugs, the most critical issue is this virus. The concealment of the specific
spreading variability is particularly important. In addition to the omissions of various methods and
measures for prevention and control of human beings, it is the cause of the generation and spread of
such viruses, especially the biochemical derivative mechanism, the formation and spread of viruses, and
the mutual induction of mutagenesis and cross-infection of various viruses and bacteria. The virus is very
active, the infection spreads very large, the cycle is long, and the outbreak is repeated. Although the
vaccine can play a major role, the complete suppression of the virus still requires unremitting efforts,
prevention and control. Closure of cities and cities, masks and other prevention and treatment methods
have played a considerable role, but in some countries and regions, the virus is still rampant, and the
epidemic and mortality rate remain high. In addition to the season, climate, environment, region,
ethnicity, animals and plants, endemic diseases, infectious diseases, frequently-occurring common
diseases and other factors, the specific and insidious transmission of the mutation and mutation of the
new coronavirus pneumonia virus is very important Pathogenesis and transmission mechanism. Closing
the city, wearing masks, measuring body temperature, including nucleic acid testing, are not completely
effective for some special cases, such as concealed patients and asymptomatic infections. This is the
focus and difficulty of epidemic prevention. Obvious cases are easy to find, while for the latter it is very
difficult and easy to be misdiagnosed and missed. The three mechanisms of mutual mutagenesis and
mutation of the new coronavirus pneumonia virus, the major discovery of the medical scientist virologist
Fangruida medical science, is of special significance for the study of the prevention and treatment of new
coronavirus pneumonia. Pathogens, pathogens, pathology, vaccines, drugs, etc. are also significant
The common side effects of mRNA (messenger ribonucleic acid) vaccines (such as fever, nausea, etc.) may
be the cause of the death of these frail elderly people. The risk of the vaccine is very small. Only in a few
cases, especially for the elderly with poor health, the side effects may cause the elderly to get worse.
China’s health authorities have stepped up efforts to contain the resurgence of new crown cases, and
China is currently facing its worst rebound since the first outbreak at the beginning of last year. There has
been a serious rebound of the epidemic in urban and rural areas in some areas.
Some cities in northern provinces, such as Hebei, Heilongjiang, and Jilin, have established temporary
isolation facilities, imposed lockdown measures on millions of residents, and conducted rounds of full-
staff testing.
The epidemic situation in Europe, the United States and other countries is also very serious, and the
epidemic situation in China has rebounded severely. These data and statistical studies on a large number
of cases, as well as the genetic sequencing of various viruses, including studies on newly discovered
various mutant virus strains, show that; 1. Origin 2. Genetic variation of the virus 3. Virulence and spread
of the virus strain 4. The effectiveness and safety of the vaccine 5. The spread and occult nature of the
new coronavirus and various virus mutations 6. Under certain circumstances, the new coronavirus
progenitor Inducing mutagenesis with various germs, causing the epidemic to continue to spread. This is
the most important factor. Of course, it also includes errors in prevention and control, regions,
population, climate, animals and plants, epidemics and infectious diseases. The use of effective drugs, the
protection of susceptible people, etc. 7. A large number of cases proved that the specific transmission of
new coronavirus pneumonia and the new coronavirus, the specific invisibility and previous coronaviruses
have their particularities, the virus is not easy to inactivate, difficult to detect, even nucleic acid testing,
etc. Sometimes it is not easy to complete accurate verification For example, asymptomatic infections,
concealed patients are difficult to be completely discovered or misdiagnosed and missed, so the epidemic
has spread repeatedly, the number of patients has increased, and the number of deaths has been rising.
Although countries around the world have adopted stricter control measures, such as closing the city,
wearing masks, measuring body temperature, negative nucleic acid tests, taking drugs and injecting
various vaccines, etc., the virus is still very active, and epidemic prevention still faces serious challenges.
8. The new coronavirus pandemic, the virus continues, spreads widely, and the death toll is huge, which is
no different from the previous major plagues in the world. The changes in the natural universe, the
pollution of the air environment, the activity of microorganisms, the use of a large number of harmful
substances, the defects of human biological evolution, the loss of human gene cells and some non-
adaptive mutations or degradation, etc., will also make various viruses more Rampant (the specific
invisibility of the virus makes prevention, control and treatment more difficult). 9. The repetitive, occult,
asymptomatic transmission of the new coronavirus is difficult to detect asymptomatic (temperature
measurement, nucleic acid, etc. sometimes fail). The harm is very serious. This is the case in Europe,
America and other countries and China, and it is impossible to prevent it. Therefore, don't think that
wearing a mask to measure body temperature will close the city and close the city, and get a vaccine, etc.
It will be safe and reliable. This is also an illusion. Anti-epidemic prevention requires sustained and
unremitting efforts, which must not be taken lightly. The struggle between humans and various viruses
has been repeated for a long time. 10. The research and development of various new coronavirus drugs is
imperative. Only when vaccines and various drugs are mutually used can the disease be fundamentally
treated. This is also a very important aspect of epidemic prevention and fighting. For various drugs,
chemical modification and chemical modification can also develop various new crown drugs. The surface
of the virus has spike-like protrusions, and the spike protein is located on the top of these protrusions,
which looks like a crown, and the coronavirus gets its name. This spike protein contains certain types of
amino acids, which can use furin in the body to break down the cell wall, thereby allowing it to enter
human cells. Spike Glycoprotein (Spike, S): It is a type I transmembrane protein that is composed of a
stick-like protrusion on the surface of the virus particle. It can be broken down by S enzyme into two
functional units, S1 and S2. S1 is used to promote the binding of the virus to the host cell receptor, and
the host receptor interaction region (RBD region) to bind to the receptor. This area can bind to the ACE2
protein. If the binding is completed, the new coronavirus will infect human respiratory epithelial cells,
which will lead to pneumonia.
Hemagglutinin-esterase protein (hemagglutinin-esterase, HE): the structure of β-coronavirus (new
coronavirus), type I transmembrane protein
Membrane glycoprotein (M): It is embedded in the virus envelope through three transmembrane
domains
Envelope protein (envelope, E): transmembrane protein
Nucleocapsid (N): binds to the RNA genome in the form of beads to form a spirally symmetrical
nucleocapsid
Genome
Many hepatitis viruses and papilloma viruses can integrate into the genome of infected cells, causing mild
or no obvious symptoms, but they can continue to release virus particles to infect more cells and people.
Bird flu virus, swine flu virus, and the relatively rare cat scratch fever virus, etc. can lodge in animals, and
they may cross into the human body at any time.
Bacteria and viruses are living organisms and have the ability to inherit, mutate, and evolve.
Viruses are a type of non-cellular microorganisms that are tiny in individuals, simple in structure,
containing only a single nucleic acid (DNA/RNA), and must be parasitic in living cells and proliferate in a
replication manner. A virus is a very small life form with an extremely simple structure. The virus is highly
parasitic and completely relies on the energy and metabolic system of the host cell to obtain the
substances and energy required for life activities. It is just a big When chemical molecules stop their
activities, they can be made into protein crystals. It is a non-living body. When encountering host cells, it
will show the typical characteristics of living body by adsorbing, entering, replicating, assembling, and
releasing offspring viruses. A primitive life form of living things and non-living things.
Rabies virus and HIV have a long incubation period, and are contagious during the incubation period, and
have escaped human detection. Bacteria are larger germs, about one micron long, and ten thousand
bacteria line up one centimeter. Viruses are the smallest germs, colds, influenza, and measles are all
caused by viral infections.
virus
Viruses are between biological and non-biological, with a total length of less than 0.1 micron, and 1
million viruses are about 1 cm long. Germs are pervasive, and any place is a habitat for germs. Everyone’s
mouth and skin are affected by germs. If germs enter the blood, it can cause sepsis. Bacteria that can
make people or other organisms sick, such as typhi, anthracis, etc. Also called pathogenic bacteria or
pathogenic bacteria. For example, among animals and plants. Plant diseases can be divided into non-
infectious diseases and invasive diseases. Infectious diseases include fungal diseases, bacterial diseases,
and viral diseases. (1) Fungal diseases are the most common and most common plant diseases Kind.
Plants with fungal diseases generally produce white powder layer, black powder layer, downy mildew
layer, rust spore centipede, sclerotia, etc. If one of the above characteristics is seen on the diseased plant,
it can be preliminarily judged as a fungal disease. . (2) Bacterial diseases are the least common type of
plant diseases, but there are many bacterial diseases that have a serious impact on production, causing a
lot of production reduction or destruction of fields. Bacteria invade through the stomata, wounds, etc. of
plants, and the plants after the onset of disease generally show necrosis, decay or wilting. (3) Plant viral
diseases are also called mosaic diseases, which are second only to fungal diseases. Most plant diseases
caused by viruses are systemic diseases, that is, the whole plant exhibits yellowing, partial or whole plant
atrophy, small leaves, small fruits, dwarfing, arbuscular branches, fern-leaf abnormalities and other
pathological changes and symptom. (4) Physiological disease is a disease that affects plants due to
improper management measures. For example, the leaf color of the plant caused by lack of nitrogen is
light green, and the bottom leaves are gradually yellow and withered; the old leaves caused by potassium
deficiency are brown and green, and there are many small brown spots along the leaf margins. (5) Plant
diseases are also caused by mutual induced mutagenesis of bacteria.
In addition, the same is true in animals. 1. Spread through saliva. For example, cats and dogs suffering
from rabies, their saliva contains a large amount of rabies virus. When a cat or dog bites a person, the
virus enters the body with the saliva and causes rabies.
2. Spread by drowning. It is well known that the stool contains various germs. Pathogens such as
tuberculosis, brucellosis, and salmonellosis can all be spread by contaminating human food, drinking
water and supplies through feces. Most parasite eggs are in the feces. The cause of leptospirosis is
transmitted through urine.
3. Sick livestock and poultry often bring out viruses or germs when they have runny nose, sneezing and
coughing, and form infectious droplets in the air to spread diseases.
4. The whole body coat and skin scales of livestock and poultry often contain bacteria on the table and
bed, which may cause comorbidities from them. Human and livestock diseases include various diseases
caused by pathogens such as viruses, bacteria, chlamydia, rickettsiae, mycoplasma, spirochetes, fungi,
protozoa and worms. 5. Other transmissions 6. Most animal diseases are closely related to mutual
induced mutagenesis of viruses and bacteria, of course, there is a difference between primary and
secondary.
According to relevant literature records, there are more than 200 types of animal infectious diseases,
more than half of which can be transmitted to humans, and more than 100 types of parasitic diseases can
also infect humans. There are more than 250 kinds of infectious diseases and parasitic animal diseases
that have been confirmed by humans and animals in the world, for example, viral infectious diseases,
bacterial infectious diseases, animal biochemistry, animal infectious diseases, animal microbiology,
animal immunology and many more. As for anthropology, modern medicine, virology, bacteriology,
quantum biochemistry, etc., there are many more. From the appearance of the new coronavirus
pneumonia, there is not too much speciality, but through a large number of case pathological studies and
analysis, the production and spread of the new coronavirus and the mutual induced mutagenesis of
various viruses and bacteria are significantly related. Questionable, undisputed scientific proof. Animal
infectious diseases are also important evidence.
In the new crown pneumonia epidemic, the concealed transmission of "asymptomatic infections" has
been paid attention to for the first time. The virus hides in the population in this way, which greatly
hinders the detection and control of infected persons.
Global statistics (main countries)
The common side effects of mRNA (messenger ribonucleic acid) vaccines (such as fever, nausea, etc.) may
be the cause of the death of these frail elderly people. The risk of the vaccine is very small. Only in a few
cases, especially for the elderly with poor health, the side effects may cause the elderly to get worse.
China’s health authorities have stepped up efforts to contain the resurgence of new crown cases, and
China is currently facing its worst rebound since the first outbreak at the beginning of last year. There has
been a serious rebound of the epidemic in urban and rural areas in some areas.
Some cities in northern provinces, such as Hebei, Heilongjiang, and Jilin, have established temporary
isolation facilities, imposed lockdown measures on millions of residents, and conducted rounds of full-
staff testing.
The epidemic situation in Europe, the United States and other countries is also very serious, and the
epidemic situation in China has rebounded severely. These data and statistical studies on a large number
of cases, as well as the genetic sequencing of various viruses, including studies on newly discovered
various mutant virus strains, show that; 1. Origin 2. Genetic variation of the virus 3. Virulence and spread
of the virus strain 4. The effectiveness and safety of the vaccine 5. The spread and occult nature of the
new coronavirus and various virus mutations 6. Under certain circumstances, the new coronavirus
progenitor Inducing mutagenesis with various germs, causing the epidemic to continue to spread. This is
the most important factor. Of course, it also includes errors in prevention and control, regions,
population, climate, animals and plants, epidemics and infectious diseases. The use of effective drugs, the
protection of susceptible people, etc. 7. A large number of cases proved that the specific transmission of
new coronavirus pneumonia and the new coronavirus, the specific invisibility and previous coronaviruses
have their particularities, the virus is not easy to inactivate, difficult to detect, even nucleic acid testing,
etc. Sometimes it is not easy to complete accurate verification For example, asymptomatic infections,
concealed patients are difficult to be completely discovered or misdiagnosed and missed, so the epidemic
has spread repeatedly, the number of patients has increased, and the number of deaths has been rising.
Although countries around the world have adopted stricter control measures, such as closing the city,
wearing masks, measuring body temperature, negative nucleic acid tests, taking drugs and injecting
various vaccines, etc., the virus is still very active, and epidemic prevention still faces serious challenges.
8. The new coronavirus pandemic, the virus continues, spreads widely, and the death toll is huge, which is
no different from the previous major plagues in the world. The changes in the natural universe, the
pollution of the air environment, the activity of microorganisms, the use of a large number of harmful
substances, the defects of human biological evolution, the loss of human gene cells and some non-
adaptive mutations or degradation, etc., will also make various viruses more Rampant (the specific
invisibility of the virus makes prevention, control and treatment more difficult). 9. The repetitive, occult,
asymptomatic transmission of the new coronavirus is difficult to detect asymptomatic (temperature
measurement, nucleic acid, etc. sometimes fail). The harm is very serious. This is the case in Europe,
America and other countries and China, and it is impossible to prevent it. Therefore, don't think that
wearing a mask to measure body temperature will close the city and close the city, and get a vaccine, etc.
It will be safe and reliable. This is also an illusion. Anti-epidemic prevention requires sustained and
unremitting efforts, which must not be taken lightly. The struggle between humans and various viruses
has been repeated for a long time. 10. The research and development of various new coronavirus drugs is
imperative. Only when vaccines and various drugs are mutually used can the disease be fundamentally
treated. This is also a very important aspect of epidemic prevention and fighting. For various drugs,
chemical modification and chemical modification can also develop various new crown drugs. The surface
of the virus has spike-like protrusions, and the spike protein is located on the top of these protrusions,
which looks like a crown, and the coronavirus gets its name. This spike protein contains certain types of
amino acids, which can use furin in the body to break down the cell wall, thereby allowing it to enter
human cells. Spike Glycoprotein (Spike, S): It is a type I transmembrane protein that is composed of a
stick-like protrusion on the surface of the virus particle. It can be broken down by S enzyme into two
functional units, S1 and S2. S1 is used to promote the binding of the virus to the host cell receptor, and
the host receptor interaction region (RBD region) to bind to the receptor. This area can bind to the ACE2
protein. If the binding is completed, the new coronavirus will infect human respiratory epithelial cells,
which will lead to pneumonia.
Hemagglutinin-esterase protein (hemagglutinin-esterase, HE): the structure of β-coronavirus (new
coronavirus), type I transmembrane protein
Membrane glycoprotein (M): It is embedded in the virus envelope through three transmembrane
domains
Envelope protein (envelope, E): transmembrane protein
Nucleocapsid (N): binds to the RNA genome in the form of beads to form a spirally symmetrical
nucleocapsid
Genome