GENERIC BRAND CLASSIFIC INDICATION CONTRAINDIC MECHANISM OF DOSAGE AND ADVERSE NURSING

NAME NAME ATION ATION ACTION FREQUENCY EFFECTS CONSIDERATION

Ceftriaxone Rocephin  Pharmacologi For treatment of: Contraindicated Bactericidal; inhibits Maximum dose: CNS: headache, Before:
sodium c: > Lower respiratory with allergy to synthesis of 4g/day dizziness, > check doctor’s order
3rd generation infections caused cephalosporin or bacterial cell wall, Minimum dose: lethargy > perform handwashing
Patient’s cephalosporin bystreptococcus penecillins causing cell death. 50-75 mg/kg/day GI: nausea, > introduce drug to the patient
dose: pneumoniae Precaution: Available forms: vomiting, and educate her about its
700 mg IV Therapeutic: > acute bacterial Use cautiously Powder for injection – diarrhea, purpose and importance
infusion OD Antibiotic otitis media with renal failure, 2 g; injection – 1, 2g anorexia, > assess for hepatic and renal
ANST > UTIs caused by lactation, pseudomembrano impairment, lactation,
E. coli pregnancy us colitis pregnancy
> Gonorrhea GU: > assess skin status, LFTs,
> intra-abdominal nephrotoxicity renal function tests, culture of
infections Hematologic: affected area, sensitivity tests
> PID caused by N. bone marrow During:
gonorrhoeae depression – > administer the right drug at
> skin and skin decrased WBC the right dose
structure infections count,decreased > check the patency of the IV
> septicaemia platelets, site and IV line
> bone and joint decreased Hct > have vitamin K ready in case
infections Hypersensitivity: hypoprothrombinemia occurs
> meningitis ranging from rash > do not mix ceftriaxone with
> Lyme disease to fever to any other antimicrobial drug
anaphylaxis > discontinue if
Patient’s actual hypersensitivity reaction
indications: Local: pain, occurs
> postoperative abscess at After:
prophylaxis for injection site > educate patient to avoid
potentially Others: alcohol while taking this drug
contaminated superinfections, and for 3 days after because
surgical procedure disulfram-like severe reactions often occur
(1o LSTCS + BTL) reaction with > monitor ceftriaxone blood
alcohol levels in patients with severe
renal impairment and in
patients with renal and hepatic
impairment
> report severe diarrhea,
difficulty breathing, unusual
tiredness or fatigue, pain at
injection site
> document and record.