A Drug Study on

Sangobion

In Partial Fulfillment of the

Requirements in MCN- RLE

Maternal and Child Nursing Rotation

Submitted to:

Mylahrose Jovita Nazareno Acaba. RN. MN.

Clinical Instructor

Submitted by:

Micaella Monique U. Leonardo. St.N.

BSN 2M – Group 1

December 03, 2020

Generic Name: Ferrous Gluconate

Brand Name:

 Sangobion

Route of administration: Oral

Classification: Antianemics

Mode of Action:

 Required for production of hemoglobin, which is necessary for oxygen transport

to cells.
 Sangobion is the drug choice for anemia, and is also supplemented with Sorbitol
to prevent constipation. Iron in high dosage and well tolerated form is
indispensable for the formation of hemoglobin. Together with other hematopoietic
factors and iron absorption enhancing factors.

Ordered dose and frequency:

Sangobion Iron: One to two capsules daily during or after meals, unless otherwise
prescribed by the physician.

Sangobion Kids:
  1 teaspoonful of syrup daily to prevent deficiencies of iron and of B vitamins
contained in the preparation.
 To treat an iron deficiency determined by the physician, 3-6 teaspoonfuls of
syrup are taken daily.
 ≥1 year: 1.2 mL. 6-12 months: 1 mL. <6 months: As prescribed by the physician.

Suggested dose (by manufacturer):

 The recommended dose is one (1) caplet daily on an empty stomach.

Indication:

 Prevention and treatment of wide range anemia; iron deficiency anemia; anemia
during pregnancy, growth, convalescence and senility; megaloblastic and
macrocytic hyperchromic anemias; alimentary anemia; prophylaxis against
anemia in blood donors.
 Iron deficiency anemia in children.
 Supplementation of iron and folic acid for anemia during growth period of babies.
 Dietary supplement for iron.

Contraindication:

 Undiagnosed anemias.
 Hemochromatosis, hemosiderosis, hemolytic anemia (Iron).
 Uncontrolled hypertension (darbepoetin, epoetin, and peginesatide).

SE/AE:

 Diarrhea/ constipation
 Sleepiness
 Abdominal bloating
  Temporary faintness
 Nausea
 Feeling of swelling of entire body

Drug interaction:

 Drug-drug- Antacids, aluminum-containing phosphate binders, cholestyramine,

cimetidine, vitamin E: Decreases ferrous fumarate absorption. Separate doses by
1- to 2-hour intervals.

Chloramphenicol: Increases response to iron therapy. Monitor patient carefully.

Doxycycline: May interfere with ferrous fumarate absorption even when doses
are separated. Avoid use together.

L-thyroxine: May decrease L-thyroxine absorption. Separate doses by at least 2

hours. Monitor thyroid function.

Levodopa, methyldopa: May decrease absorption of these drugs. Monitor patient

carefully.

Penicillamine: Decreases penicillamine absorption. Separate doses by at least 2

hours.

Quinolones: May decrease quinolone absorption. Monitor patient closely.

Tetracycline: Inhibits absorption of both drugs. Give tetracycline 3 hours after or

2 hours before iron supplement.

Vitamin C: Increases iron absorption. May be used as a beneficial drug

interaction.

 Drug-herb- Black cohosh, chamomile, feverfew, gossypol, hawthorn, nettle,

plantain, St. John’s wort: Decreases iron absorption. Discourage use together.
 Drug-food- Cereals, cheese, coffee, eggs, milk, tea, whole-grain breads, yogurt:
May impair oral iron absorption. Discourage use together.
Nursing responsibilities:

 Lab tests: Monitor Hgb and reticulocyte values during therapy. Investigate the
absence of satisfactory response after 3 wk of drug treatment.
 Continue iron therapy for 2–3 mo after the hemoglobin level has returned to
normal (roughly twice the period required to normalize hemoglobin
concentration).
 Monitor bowel movements as constipation is a common adverse effect.
 Instruct patient to avoid concurrent use of alcohol or OTC medicine without
consulting the physician.
 Instruct the patient/give on an empty stomach if possible because oral iron
preparations are best absorbed then (i.e., between meals). Minimize gastric
distress if needed by giving with or immediately after meals with adequate liquid.
 Inform patient that taking the iron supplement will cause a dark green or black
stool.
 For breast-feeding women; Iron supplements are commonly recommended, with
no adverse effects have been documented.
 Ascorbic acid increases absorption of iron. Consuming citrus fruit or tomato juice
with iron preparation (except the elixir) may increase its absorption.
 To promote absorption, tell patient to take tablets with orange juice.
 Consult your doctor if you observe any of the following side-effects, especially if
they do not go away.
 Caution parents to store drug securely away from children.
Bibliography:

Mims.com (2020). Sangobion. Retrieved December 3, 2020 from,

https://www.mims.com/philippines/drug/info/sangobion?type=full

Glowm.com (2020). Ferrous gluconate. Retrieved December 3, 2020 from,

https://www.glowm.com/resources/glowm/cd/pages/drugs/f010.html

Tabletwise.com (2020). Sangobion Capsule. Retrieved December 3, 2020 from,

Sangobion Capsule - Uses, Side-effects, Reviews, and Precautions - Merck Indonesia
Tbk - TabletWise

Vallaerand, A.H. & Sanoski, C.A. (2019). Davis's Drug Guide for Nurses. Philadelphia,
PA. F. A. Davis Company.