ARANDELA, MICHAELA JAN G.

BS MLS 2D

ACTIVITY 4. AMINO ACIDS AND PEPTIDES.

1. FILL IN THE BLANKS

a. Monomers or building blocks of proteins are known as _amino acids_.

b. Amino acids differ from each other due to the _side chain or R- group.

c. Molecules that have positive and negative charges in their structures with zero net charge
are also called __zwitterion_.

d. Because of the presence of a _chiral__ C in its structure, an amino acid (except glycine) can
have 2 isomers namely _levorotatory (L-)__ and _dextrorotatory (D-)_ isomer.

e. The basic amino acids are _lysine__, _histidine_, and __argenine__.

f. The acidic amino acids are _glutamic acid (glutamate)__, and _aspartic acid (aspartate)__.

g. Phenylalanine is an example of an _aromatic__ amino acid.

h. The amino acids cysteine and methionine contain this element __sulfur (S)__ other than C, H,
O, and N.

i. These amino acids _valine_, _leucine__, and _isoleucine __ are examples of neutral, branched
chain amino acids.

j. Amino acids in peptides and proteins are joined together by peptide bonds that result from
__condensation__ reaction.

2. CONSIDER THE PEPTIDE H2N – M-A-T-I-N-I-K – COOH

a. The peptide is a __heptapeptide__ for the number of amino residues in its structure.

b. The N- terminal amino acid is __methionine___.

c. The C-terminal amino acid is ___lysine__.

d. The peptide contains this branched chain amino acids __isoleucine__ and __isoleucine__.

e. The pI of this peptide is _10___.

f. At pH 7.5 this peptide has net __positive__ (positive or negative) charge.