Status of the Thyroid Ultrasound Examination (released on January 15, 2021)

1. Preliminary Baseline Screening (First Round) (Tallied as of March 31, 2018)

【Conducted in FY2011-2013】
Primary examination (completed on April 30, 2015)
 Target population 367,637
 Participants 300,472 (81.7% participation rate)
 Completed test results 300,472 (100.0% completion rate)
 Test result categories
A (A1) : 154,605 (51.5%)
(A2): 143,573 (47.8%)
B: 2,293 ( 0.8%)
C: 1 ( 0.0%)

Confirmatory examination (as of March 31, 2018)

 Target population 2,293
 Participants 2,130 (92.9% participation rate)
 Completed test results 2,091 (98.2% completion rate)
547 participants underwent fine-needle aspiration cytology (FNAC)
Summary of FNAC results
 Suspicious or malignant 116
 Male : Female 39 : 77
 Average age 17.3±2.7 (8-22), 14.9±2.6 (6-18) at the accident time
 Average tumor diameter 13.9±7.8 mm (5.1-45.0 mm)

Age and sex distribution of 116 suspicious or malignant cases

[Age as of March 11, 2011]

[Age on the date of confirmatory examination]

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2. Full-Scale Screening (Second Round) (as of March 31, 2018)
【Conducted in FY2014-2015】
Primary examination
 Target population 381,244
 Participants 270,540 (71.0% participation rate)
 Completed test results 270,529 (100.0% completion rate)
 Test result categories
A (A1): 108,718 (40.2%)
(A2): 159,584 (59.0%)
B: 2,227 ( 0.8%)
C: 0 ( 0.0%)

Confirmatory examination
 Target population 2,227
 Participants 1,874 (84.1% participation rate)
 Completed test results 1,826 (97.4% completion rate)
207 participants underwent FNAC
Summary of FNAC results
 Suspicious or malignant 71
 Male : Female 32 : 39
 Average age 16.9±3.2 (9-23), 12.6±3.2 (5-18) at the accident time
 Average tumor diameter 11.1±5.6 mm (5.3-35.6 mm)

Age and sex distribution of 71 suspicious or malignant cases

[Age as of March 11, 2011]

[Age on the date of confirmatory examination]

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3. Full-Scale Screening (Third Round) (as of March 31, 2020)
【Conducted in FY2016-2017】
Primary examination
 Target population 336,670
(Excluding those born in FY1992-1993, eligible for Age 25 Milestone Screening)
 Participants 217,921 (64.7% participation rate)
 Completed test results 217,920 (100.0% completion rate)
 Test result categories
A (A1): 76,433 (35.1%)
(A2): 139,986 (64.2%)
B: 1,501 ( 0.7%)
C: 0 ( 0.0%)

Confirmatory examination
 Target population 1,501
 Participants 1,101 (73.2% participation rate)
 Completed test results 1,060 (95.6% completion rate)
78 participants underwent FNAC
Summary of FNAC results
 Suspicious or malignant 31
 Male : Female 13 : 18
 Average age 16.3±2.9 (12-23), 9.6±2.9 (5-16) at the accident time
 Average tumor diameter 12.9±6.4 mm (5.6-33.0 mm)

Age and sex distribution of 31 suspicious or malignant cases

[Age as of March 11, 2011]

[Age on the date of confirmatory examination]

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4. Full-Scale Screening (Fourth Round) (as of June 30, 2020)
【Conducted in FY2018-2019】
Primary examination
 Target population 294,240
(Excluding those born in FY1992-1995, eligible for Age 25 Milestone Screening)
 Participants 181,005 (61.5% participation rate)
 Completed test results 180,978 (100.0% completion rate)
 Test result categories
A (A1): 60,901 (33.7%)
(A2): 118,715 (65.6%)
B: 1,362 ( 0.8%)
C: 0 ( 0.0%)

Confirmatory examination
 Target population 1,362
 Participants 819 (60.1% participation rate)
 Completed test results 758 (92.6% completion rate)
64 participants underwent FNAC
Summary of FNAC results
 Suspicious or malignant 27
 Male : Female 11 : 16
 Average age 16.2±3.0 (9-20), 8.0±3.0 (0-12) at the accident time
 Average tumor diameter 12.8±6.1 mm (6.1-29.4 mm)

Age and sex distribution of 27 suspicious or malignant cases

[Age as of March 11, 2011] Ages 15-18 not included in the fourth round.

[Age on the date of confirmatory examination]

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5. Full-Scale Screening (Fifth Round) (as of June 30, 2020)
【Conducted in FY2020-2021】
Primary examination
 Target population 252,821
(Excluding those born in FY1992-1997, eligible for Age 25 Milestone Screening)
 Participants 564 (0.2% participation rate)
 Completed test results 41 (7.3% completion rate)
 Test result categories
A (A1): 13 (31.7%)
(A2): 27 (65.9%)
B: 1 ( 2.4%)
C: 0 ( 0.0%)

6. Age 25 Milestone Screening (as of March 31, 2020)

【Conducted in FY2017-】
Primary examination
 Target population 66,637 (those born in FY1992-1994)
 Participants 5,578 (8.4% participation rate)
 Completed test results 5,234 (93.8% completion rate)
 Test result categories
A (A1): 2,228 (42.6%)
(A2): 2,762 (52.8%)
B: 244 ( 4.7%)
C: 0 ( 0.0%)

Confirmatory examination
 Target population 244
 Participants 　　　168 (68.9% participation rate)
 Completed test results 160 (95.2% completion rate)
13 participants underwent FNAC
Summary of FNAC results
 Suspicious or malignant 7
 Male : Female 2:5
 Average age 25.3±1.0 (24-27), 17.1±0.7 (16-18) at the accident time
 Average tumor diameter 22.6±15.6 mm (10.8-49.9 mm)

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The numbers of suspicious or malignant cases and surgically confirmed cases

Overall status from the first through fourth rounds as well as Age 25 Milestone Screening
Malignant or suspicious cases 252
Surgically confirmed cases 203
[1 benign nodule, 199 papillary thyroid cancer (PTC), 1 poorly differentiated
thyroid cancer (PDTC), 1 follicular thyroid cancer, and 1 other thyroid cancer]

First round (as of March 31, 2018) 【Conducted in FY2011-2013】

Total 116 (39 males : 77 females)
(102 surgically confirmed cases: 1 benign nodule, 100 PTC, 1 PDTC)

Second round (as of March 31, 2020) 【Conducted in FY2014-2015】

Total 71 (32 males : 39 females)
(54 surgically confirmed cases: 53 PTC, 1 other thyroid cancer)

Third round (as of March 31, 2020) 【Conducted in FY2016-2017】

 FY2016 municipalities 13 (7 males : 6 females)
(11 surgically confirmed cases: 11 PTC)
 FY2017 municipalities 18 (6 males : 12 females)
(16 surgically confirmed cases: 13 PTC)

Total 31 (13 males : 18 females)

(27 surgically confirmed cases: 27 PTC)

Fourth round (as of June 30, 2020) 【Conducted in FY2018-2019】

 FY2018 municipalities 17 (7 males : 10 females)
(12 surgically confirmed case: 12 PTC)
 FY2019 municipalities 10 (4 males : 6 female)
(4 surgically confirmed case: 4 PTC)

Total 27 (11 males : 16 females)

(16 surgically confirmed cases: 16 PTC)

Fifth round (as of June 30, 2020) 【Conducted in FY2020-2021】

 FY2020 municipalities 0 (0 male : 0 female)
(0 surgically confirmed case)

Age 25 Milestone Screening (as of March 31, 2020) 【Conducted in FY2017-】

Total 7 (2 males : 5 females)
(4 surgically confirmed cases: 3 PTC, 1 FTC)