SARHAD UNIVERSITY OF SCIENCE & INFORMATION TECHNOLOGY, PESHAWAR

Department: Institute of biological sciences Program: BS MLT

Mid-Term Examination-Fall 2020

Course Title: Immunology and serology Semester: Fall 2020

Course Code: MLT-407 Time Duration: 24 Hours
Instructor’s Name: Hina Nayab Total Marks: 30 (30 % weightage)
Exam Date: 9 /Jan/2021
Student’s Name:
Registration No:
Student email:
Whatsapp Contact No:

INSTRUCTIONS:
Answer all the Questions in the same Question Paper under each question/section subsequently.
Before uploading, save the same file in this format MID EXAM_DEPARTMENT_COURSE_Student Name_Reg#.doc
Upload it at your SUIT PORTAL before the deadline. Answer Sheet sent through EMAIL will not be accepted.
The total size of this file should not exceed 5MB at the time of uploading it at portal so don’t insert images.
Just type the answers under each question, avoid inserting images and follow the instructions at SUIT Portal.
Copying, plagiarism, and sharing your answers with other students is strictly prohibited and marks will be deducted.

Attempt All Questions. Each Question Carries 10 marks. Mention the references (if any) as
footnotes or at the end after completing the question
Long answers should not be more than 7-8 lines

Q#1:
a) Role of HLA genes in immunology in detail? (4 marks)
b)Which domain of antibody defines its type and which domain is for specificity against antigen.
Also explain the rearrangement of genes for IgA. (6 marks)

Solution#1 (to be typed here by the student)

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Q#2
a) Why some individual have hypersensitivity reaction but not all? (3 marks)
b) Hypersensivity has four types I,II,III,IV. Explain one type of hypersensitivity reaction of your
choice with help of one example. Write symptoms with their description in brackets .
(7 marks)

Solution#2 (to be typed here by the student)

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Q#3.
a) Enlist mechanisms that are used to tackle a foreign body entering human body? (3 marks)
b) Briefly describe the stages in T cell development in the thymus and describe the mechanisms that
lead to self- tolerance. Explain one example of any kind of defect that leads to failure of central tolerance
and cause an autoimmune disease? (7 marks)

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Solution#3 (to be typed here by the student)

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