DRUG STUDY: RANITIDINE

DRUG ORDER NURSING

TRADE / PHARMACOLOGIC ACTION OF INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
(Generic name, dosage, RESPONSIBILITIES/
BRAND NAME DRUG CONTRAINDICATIONS THE DRUG YOUR CLIENT
route, frequency, etc.) PRECAUTIONS
Competitively inhibits gastric INDICATIONS GI: constipation, There will be an Assess stomach pain, noting
RANITIDINE ZANTAC acid secretion by blocking the Management of peptic diarrhea, abdominal evidence of duodenal characteristics, frequency
HYDROCHLORIDE effect of histamine on ulcer disease, GERD, pain ulcer healing of occurrence, triggers,
histamine h2 receptors. Both persistent dyspepsia, & things that alter/relieve
daytime and nocturnal basal patients at risk of acid CNS: headache, Decrease in the
gastric acid secretions, as well
aspiration during general dizziness, malaise, abdominal pain/ Note H. pylori, UGI, or
as food- and pengastrin- insomnia, vertigo, discomfort endoscopy findings
anesth or childbirth.
stimulated gastric acid are confusion, anxiety,
CONTRAINDICATION
inhibited. Weak inhibitor of hallucinations
Cirrhosis of the liver, impaired
cytochrome P-450 (drug
renal or hepatic function
metabolizing enzymes); thus, CV: bradycardia or
drug interactions involving tachycardia
inhibitions involving inhibition
of hepatic metabolism are not HEMATOLOGIC:
expected to occur thrombocytopenia,
granulocytopenia,
leukopenia,
pancytopenia
 DRUG STUDY : ENALAPRIL

DRUG ORDER NURSING

TRADE / PHARMACOLOGIC ACTION OF INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
(Generic name, dosage, RESPONSIBILITIES/
BRAND NAME DRUG CONTRAINDICATIONS THE DRUG YOUR CLIENT
route, frequency, etc.) PRECAUTIONS

ENALAPRIL MALEATE Enalapril (and its active INDICATIONS CV: palpitations, There will be a Record ECG, VS and weight
VASOTEC metabolite enalaprilat) inhibit Treatment of essential & hypotensions, chest decrease in BP and
angiotensin-converting renovascular HTN, CHF & pain, angina, CVA, MI, decrease in preload Monitor CBC, electrolytes,
enzyme resulting in decreased prevention of coronary cardiac arrest and afterload with renal and LFTs. Reduce
plasma angiotensin II, which ischemic events in patients CHF dose with impaired renal
leads to decreased GI: diarrhea, abdominal function
w/ left ventricular
vasopressor activity and pain, alterations in
dysfunction.
decreased aldosterone taste, anorexia, dry
secretion. The parenteral mouth, constipation,
product is enalaprilat injection CONTRAINDICATIONS dyspepsia
Angioedema, hereditary or
idiopathic. Hyperkalemia, RESPIRATORY:
renal artery stenosis, bronchitis, cough,
bilateral or in a solitary dyspnea,
kidney or renal transplant, bronchospasm, URI,
renal function impairment. pneumonia, asthma

HEMATOLOGIC:
hrmolytic anemia,
neutropenia,
thrombocytopenia,
bone marrow
depressions
 DRUG STUDY: CITICOLINE

DRUG ORDER NURSING

TRADE / PHARMACOLOGIC ACTION OF INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
(Generic name, dosage, RESPONSIBILITIES/
BRAND NAME DRUG CONTRAINDICATIONS THE DRUG YOUR CLIENT
route, frequency, etc.) PRECAUTIONS

CITICOLINE Citicoline is a complex INDICATIONS Stomach pain, To minimize the Somazine must not be
organic molecule that Cerebrovascular disorders diarrhea; hypotension, attack of sroke administered along with
CHOLINERV functions as an including ischemic stroke, tachycardia, medicaments containing
intermediate in the parkinsonism & head injury. bradycardia. meclophenoxate
biosynthesis of cell CONTRAINDICATIONS
membrane phospholipids. It Parasympathetic
is also known as CDP- hypertonia.
choline or cytidine
diphosphate choline
(cytidine 5'-
diphosphocholine). CDP-
choline belongs to the
group of biomolecules in
living systems known as
nucleotides that play
important roles in cellular
metabolism.
 DRUG ORDER NURSING
TRADE / PHARMACOLOGIC ACTION OF INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
(Generic name, dosage, RESPONSIBILITIES/
BRAND NAME DRUG CONTRAINDICATIONS THE DRUG YOUR CLIENT
route, frequency, etc.) PRECAUTIONS

CEFUROXIME Cefuroxime axetil is absorbed INDICATIONS GI disturbances, There will be a Note for reasons for
AXET from the GIT and is rapidly Infections of the bone & pseudomembranous resolution on the S&S therapy, characteristics of
hydrolyzed in the intestinal joint, upper & lower resp colitis, headache, of infection S&S, culture results,
mucosa and blood to tract, skin & soft tissue; eosinophilic & baseline assessment
cefuroxime. Absorption is surgical infections, UTI, transient increase in
enhanced in the presence of hepatic enzymes, false
gonorrhea.
food. Peak plasma +ve Coomb's test.
CONTRAINDICATIONS
concentrations are reported
Hypersensitivity to
about 2-3 hrs after an oral
dose. It is widely distributed in cephalosporins.
the body including pleural
fluid, sputum, synovial fluid
and aqueous humor, but only
achieves therapeutic
concentrations in the CSF
when the meninges are
inflamed. It crosses the
placenta and has been
detected in breast milk. It is
excreted unchanged by
glomerular filtration and renal
tubular secretion and high
concentrations are achieved in
the urine.

DRUG ORDER
TRADE / PHARMACOLOGIC ACTION OF
(Generic name, dosage,
BRAND NAME DRUG
route, frequency, etc.)
CEFTRIAXONE Ceftriaxone exerts in vitro
ROCEPHIN activity against a wide range
of gram-negative and gram-
positive microorganisms. It
is highly stable to most -
lactamases, both
penicillinases and
cephalosporinases, of gram-
positive and gram-negative
bacteria
Long-acting, broad-
spectrum cephalosporin
antibiotic
DRUG STUDY: CETRIAXONE
NURSING
INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
RESPONSIBILITIES/
CONTRAINDICATIONS THE DRUG YOUR CLIENT
PRECAUTIONS
INDICATIONS Systemic Adverse Resolution of S&S of Note for reasons for
Sepsis, meningitis; Effects: GI infection therapy, characteristics of
abdominal, biliary tract, Complaints (about S&S, culture results,
GIT, bone, joints, soft 2% of cases): Loose There will be a baseline assessment
tissue, renal, resp tract, stools or diarrhea, negative report on
ENT, genital & skin & nausea, vomiting,
culture sensitivity Assess for GI disease.
wound infections. UTI, stomatitis and
test Report any bleeding/
gonorrhea. Periop bruising, diarrhea.
glossitis.
prophylaxis of infections.
CONTRAINDICATIONS
hypersensitivity to Hematological
cephalosporins. Changes (about 2%):
Eosinophilia,
leukopenia,
granulocytopenia,
hemolytic anemia
and
thrombocytopenia.
Skin Reactions (about
1%): Exanthema,
allergic dermatitis,
pruritus, urticaria,
edema and erythema
multiforme.
 DRUG ORDER
TRADE / PHARMACOLOGIC ACTION OF
(Generic name, dosage,
BRAND NAME DRUG
route, frequency, etc.)
SIMVASTATIN Treatment of
REDUSCOLE hypercholesterolemia
(heterozygous familial &
nonfamilial) & mixed
dyslipidemia (type IIa & IIb
hyperlipoproteinemia).
NURSING
INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
RESPONSIBILITIES/
CONTRAINDICATIONS THE DRUG YOUR CLIENT
PRECAUTIONS
INDICATIONS Constipation, diarrhea, Note reasons for therapy,
Treatment of flatulence, heartburn, characteristics of S&S,
hypercholesterolemia stomach pain, culture results.
(heterozygous familial & dizziness, headache,
nonfamilial) & mixed nausea, skin rash. Assess for GI disorders
Rarely, myalgia,
dyslipidemia (type IIa & IIb
myositis or Report for any
hyperlipoproteinemia).
rhabdomyolysis. bleeding/bruising
CONTRAINDICATIONS
Active hepatic disease.

DRUG ORDER
TRADE / PHARMACOLOGIC ACTION OF
(Generic name, dosage,
BRAND NAME DRUG
route, frequency, etc.)
Omeprazole suppresses
PEPTISOLV gastric acid secretion by
OMEPRAZOLE specific inhibition of the
enzyme system
hydrogen/potassium
adenosine triphosphatase
(H+/K+ ATPase) present on
the secretory surface of the
gastric parietal cell.
DRUG STUDY : OMEPRAZOLE
NURSING
INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
RESPONSIBILITIES/
CONTRAINDICATIONS THE DRUG YOUR CLIENT
PRECAUTIONS
INDICATIONS Headache, abdominal Promotion of ulcer List reasons for therapy,
Treatment of heartburn & pain, diarrhea N&V, healing frequency and
other symptoms associated URTI, rash characteristics of S&S
w/ GERD. Erosive Relief of pain
esophagitis, gastric CNS: anxiety disorders, Record abdominal
vertigo, insomnia, Lower gastric acid assessments,
hypersecretory condition,
nervousness production radiographic/endoscopic
Zollinger-Ellison syndrome,
findings
systemic mastocytosis, HEPATIC: overt liver
multiple endocrine disease cholestatic Monitor CBC
adenoma & peptic ulcer.
CONTRAINDICATIONS CV: angina,
Chronic hepatic disease. tachycardia,
bradycardia,
palpitation, peripheral
edema, elevated BP
 DRUG STUDY : ASPIRIN
DRUG ORDER
TRADE / PHARMACOLOGIC ACTION OF
(Generic name, dosage,
BRAND NAME DRUG
route, frequency, etc.)
ASPIRIN ASPILET Aspirin is an analgesic, anti-
inflammatory and antipyretic.
It inhibits cyclooxygenase,
which is responsible for the
synthesis of prostaglandin and
thromboxane. It also inhibits
platelet aggregation.
NURSING
INDICATIONS AND ADVERSE EFFECTS OF DESIRED ACTION ON
RESPONSIBILITIES/
CONTRAINDICATIONS THE DRUG YOUR CLIENT
PRECAUTIONS
INDICATIONS Fever, hypothermia, There will be a relief For pain, rate and
Aspilet Suspected acute MI; thirst. Dysrythmias, of pain/discomfort to determine the type,
Aspilet/EC Prophylactic hypotension, the patient location, and pattern of
treatment of thromboembolic tachycardia. Agitation, pain, if unusual, or if
disorders, MI, transient cerebral edema, coma, There will be a recurring
ischemic attacks & stroke. For confusion, dizziness, decrease fever and
the secondary prevention of headache, subdural or vascular mortality Determine history of peptic
CV disease in DM patients esp intracranial ulcers or bleeding tedency
those w/ history of MI, hemorrhage, lethargy,
vascular bypass procedure, seizures. Dehydration,
stroke or transient ischemic hyperkalemia,
attack & angina & those w/ metabolic acidosis,
additional risk factors: HTN, resp alkalosis,
smoking, dyslipidemia & dyspepsia, GI bleeding,
family history of CV disease. ulceration &
Revascularization procedures. perforation, nausea,
Pregnancy-induced HTN. vomiting, transient
CONTRAINDICATIONS hepatic enzyme
Asthma, rhinitis & nasal elevations, hepatitis.
polyps. History of active peptic
ulcer disease. Hypersensitivity.