Drug Study Uses

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Mannitol 100cc every 4 hours as side drip, fast drip initially of 100cc,

Mannitol is a sugar alcohol solution which is sometimes effective in reducing brain swelling after
head injury.

Mannitol injection is also used to reduce swelling and pressure inside the eye or around the
brain.

Dexamethasone (Decadron) 8 mg IVP now the 4 mg IVP every 6 hours,

Dexamethasone is a steroid drug that has proven benefit in reducing the swelling (oedema)
caused by some brain tumours. Swelling associated with brain tumours may contribute to the
symptoms produced by the tumour including headaches and neurological deficits (such as
weakness and loss of speech).

Dexamethasone (Decadron™) and prednisone are some corticosteroid drugs. These steroids
can temporarily improve neurological symptoms by reducing brain swelling but in most cases do
not directly treat the tumor. Because steroids are hormones, their long-term use requires close
monitoring.

Dexamethasone is the corticosteroid most commonly used for the management of vasogenic
edema and increased intracranial pressure in patients with brain tumours. It is also used after
surgery (before embarking on radiotherapy), particularly in patients whose tumours exert
significant mass effect.

Ranitide (Zantac) 50mg IVP now then every 8 hours,

Ranitidine Solution for Injection is indicated for the treatment of duodenal ulcer, benign gastric
ulcer, post - operative ulcer, and of Zollinger - Ellison Syndrome . In the management of
conditions where reduction of gastric secretion and acid output is desirable, such as reflux
oesphagitis.

Ranitidine injection is used in people who are hospitalized to treat certain conditions in which
the stomach produces too much acid or to treat ulcers (sores in the lining of the stomach or
intestine) that were not successfully treated with other medications.

Captopril (Capoten) 25 mg tab (pulverized) SL,

Captopril is used alone or in combination with other medications to treat high blood pressure
and heart failure.

Captopril is used to treat high blood pressure (hypertension). Lowering high blood pressure
helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure,
protect the kidneys from harm due to diabetes, and to improve survival after a heart attack.
Captopril works by opening your blood vessels. This allows blood to flow more easily and
decreases how hard your heart has to pump. These effects lower your blood pressure levels,
improve your heart's ability to pump blood, and improve blood flow in your kidneys.

Nicardipine drip 10ml/ 1 amp incorporated to present IV with MAP of equal or greater
than 160 and target BP is 150/90,

Nicardipine, a dihydropyridine Ca channel blocker, acts as an arterial dilator thereby increasing


blood flow to the brain and ameliorating cerebral vasospasm following aneurysmal SAH. It also
has also been shown to have a positive effect on neuronal function in patients with ischemia.

Cardene I.V. (nicardipine hydrochloride) is a calcium channel blocker indicated for the short-
term treatment of high blood pressure (hypertension) for patients who cannot take the
medication orally.

If desired blood pressure reduction is not achieved at this dose, the infusion rate may be
increased by 25 mL/hr (2.5 mg/hr) every 5 minutes (for rapid titration) to 15 minutes (for gradual
titration) up to a maximum of 150 mL/hr (15 mg/hr), until desired blood pressure reduction is
achieved.

phenytoin (Dilantin) 100 mg PO TID,

Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may
begin during or after surgery to the brain or nervous system. Phenytoin is in a class of
medications called anticonvulsants. It works by decreasing abnormal electrical activity in the
brain.

Phenytoin works by slowing down impulses in the brain that cause seizures. Phenytoin is used
to control seizures.

Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic
drug). It works by reducing the spread of seizure activity in the brain.

Acetamenophen ( Tylenol) 1 tab 500 mg every 4 hours PO.

Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches,
menstrual periods, colds and sore throats, toothaches, backaches, and reactions to
vaccinations (shots), and to reduce fever.

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