Name: Ismael Jaani BSM- 3 Date: October 20,2020

DRUG STUDY
Drug Order Mechanism of Action Indication Contraindications Side Effects / Adverse Responsibilities in
Effects administering the drug

Generic Name: Selectively blocks the Treatment of  Contraindicated CNS: Headache, BEFORE:
LOSARTAN binding of angiotensin II hypertension, alone or in in patient’s dizziness, syncope,  Assess patient’s
to specific tissue combination with other hypersensitive to insomnia health history.
receptors found in the antihypertensive drug. CV: Hypotension  Assess patient’s
Brand Name: vascular smooth muscle Agents. Breastfeeding Dermatologic: Rash, blood pressure.
Cozaar and adrenal gland; this Treatment of diabetic isn’t urticaria, pruritus,  Assess patient’s
action blocks the neuropathy with an recommended alopecia, dry skin renal function.
vasoconstriction effect of elevated serum creatinine during losartan GI: Diarrhea, abdominal DURING:
the renin-angiotensin and proteinuria in therapy. pain, nausea,  Monitor patient’s
Dosage: system as well as the patients with type 2  Use cautiously in constipation, dry mouth intake and output.
Give 50mg 1tab release of aldosterone (non–insulin-dependent) patient’s with Respiratory: URI  Administer drug
leading to decreased diabetes and a history of impaired renal or symptoms, cough, sinus at daytime.
blood pressure. hypertension hepatic function. disorders AFTER:
Route: Other: Back pain, fever,
 Drugs that act  Be alert for
PO gout, muscle weakness
directly on the adverse reaction.
renin angiotensin Monitor patient’s
system(such as Interactions sleeping pattern.
Frequency: Drug-drug
losartan) can
OD Decreased serum levels
cause fetal and Patient’s teaching:
neonatal and effectiveness if taken
morbidity and concurrently with > Take drug without
death when given phenobarbital regard to meals.
to women in Losartan is converted to >Do not stop taking this
second or third an active metabolite by drug without consulting
trimester of cytochrome P450-3A4. your health care provider.
pregnancy. These Drugs that inhibit 3A4 >Tell patient to take drug
problems haven’t (ketoconazole, at morning to prevent
been detected fluconazole, diltiazem) insomnia at night.
when exposure may decrease the >Stop medication if
Name: Ismael Jaani BSM- 3 Date: October 20,2020

was limited to antihypertensive effects adverse reaction occur,

the first of losartan. notify prescriber
trimester. If immediately.
pregnancy is
suspected, notify
prescriber
because drug
should be
stopped.