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Nephrectomy Surgical Approaches: Angiomyolipomas
Nephrectomy Surgical Approaches: Angiomyolipomas
Hinmann CHAPTER 8 Surgical Approaches for Open Renal Surgery, Including Open
Radical Neph rectomy 63
Angiomyolipomas Treatment
Patients with angiomyolipomas resulting from tuberous sclerosis are at risk for hemorrhage
and impaired renal function (Bissler et al., 2016).
For many years, the threshold diameter for intervention has been more than 4 cm. Recent data
in adult patients with sporadic angiomyolipoma suggest that intervention can be delayed until
the diameter exceeds 6 cm (Kuusk et al., 2015). The International TSC Consensus Group
recommends intervention for lesions larger than 3 cm in diameter (Kingswood et al., 2016).
Lesions in TSC patients that are larger than 3 cm and enlarging appear to be at greatest risk
for bleeding. The first-line treatment for children with growing lesions (Fig. 53.13) is
with mTOR inhibitor, and embolization or surgery are second-line treatments.
Historically, a size of 4 cm or greater and being of childbearing age were used as indications
for intervention because of a concern for spontaneous hemorrhage and pain. AML less than
4 cm in size are expected to be asymptomatic and unlikely to bleed, and therefore active
surveillance is an option.
Mapping biopsy (dome, trigone, anterior, posterior, lateral kanan kiri bladder wall)
CAPD insertion
New catheters have been devised to prevent obstruction (4, 5). Their intra peritoneal portions
have discs or balloons to keep the tip in the true pelvis and protect it from omental wrapping.
It also seemed logical to direct the tunnel cranially if this would make migration less likely.
After this tunnel direction was employed more frequently in our institution we had the
impression that exit infections became more frequent and difficult to treat, and began to
suspect that cranial tunnel direction facilitated exit-site contamination and impeded the
drainage of pus.