DRUG REFRERENCES

1 BACKGROUND

1.1 D DOSE CHILD: PI( MAY OR MAY NOT) , LEXICOMP OFF LABEL
SECTION OF GENERAL D INFORMATION, HARRIET LANE

1.2 ADMINISTARTIN RECOMMENDATIN ( CRUSH TABELT) OR

PRODUCY AVAILABILITY (SOLUTION ) IN PI REFLECTED IN GDI, IF
FORMULATION NOT AVAILABLE FOR CHILD, USE USP795 MASTER
FORMULA RECPIE FOR ORAL KEPPRA LIQUID

1.3 D INTERACTION W NATRUAL PRODUCT(SAFETY MELATONIN W

KEPPRA) IN MOST GDI+SPECIFIC NATRUAL MEDICINE RESOURCE
2 PACKAGE INSERT

2.1 BW, RECNT MAJOR CHANGES, INDICATION AND USAGE, DOSAGE

AND ADMININSTRATION, DOSAGE FORMS AND STRENGTHS,
CONTRAINDICATION, WARNING AND PRECUTION, ADVERSE RX, DI, USE
IN SPECIFIC POPULATIONS, D ABUSE AND DEPENDENCE,
OVERDOSAGE/TOXICOLOGY, PHARMACOLOGY/MECHANISM OF
ACTION, ADDITIONAL CATEGORIES(PHARMACOKINETICS AND
PHARMACODYNAMICS, CLINICAL STUDIES,STORAGE AND HANDLING,
PT COUNSELING INFORMATION
2.1.1 D SAFETY INFORMATION:
BW:STRICEST WARNING, DEATH OR PERMANENT DISABILITY(VTE,DEATH FROM
STROKE W RALOXIFENE)
CI:PT HAS CI D, CAN NOT BE USED(RISK OUTWEIGH BENEFIT) (HISTORY OF VTE W
RALOXIFENE)
WARNING AND PRECAUTIONS: RXS RESULT DEATH, HOSPITILAZTION, MEDICAL
INTERVENTION, DISABILITY OR TERATOGENCITY(RALOXIFENE WARNING FOR
VTE)(GET DVT EVISTA IF SLEEP ON COUCH)
ADVERSE RXS: UNDESIRABLE, UNCOMFORTABLE OR DANGEROUS EFFCTS FROM D(
ARTHRALGIA, HOT FLASHES FROM RALOXIFENE)

2.2 1-FDA APPROVED DRUG INFORMATION:DRUGS@FDA, FDA

PROVIDES PIS TO NLM:2-DAILY MED(NLM) , WHICH PUTS CURRENT PIS
ON #DAILYMED WEBSITE AND 3- DRUG MANFACTURER
WEBSITE(WWW.PFIZER.COM) 4- WEBSITE URL DRUG BRAND
NAME(WWW.ELIQUIS.COM)W NEWER D

2.3 PIS FOUND ON FDA WEBSITE, DAILY MED SIMPLER, TOP OF

BOTTLE
2.4 FDA APPROVES D AND THEIR ABELILNG, PI IS PART OF
LABELING, PIS DO NOT CONTAIN INFORMATION NOT APPROVED BY
FDA, SUCH AS OFF LABEL US, OR DRUGS COST
2.5 PI IS FDA APPROVED D INFORMATION IS PART OF D LABEL, FDA
PROVIDES PIS TO NLM WHICH PUTS CURRENT PIS ON DAILYMED
WEBSITE+MANUFATURER WEBSITE WHICH WILL HAVVE PIS FOR
MANUFACTURE DRUG, PIS LOCATED ON FDA WEBSITE NOT ACCESSED
COZ SERACH FUNCTION SIMPLER ON DAILYMED, BOTH HAVE
CURRENT PIS+TOP BOTTLE
3 GENERAL DRUG INFORMATION RESOURCES:TRISSEL IV D
COMPATIBIILTY AND STABILITY DATA, D CLASS COMPARISONS,
NATURAL PRODUCT, DRUG TABLET/CAPSULE IDENTIFICATION AND
INTERNATIONAL DRUG NAMES, MOST SITES: D PRICING WITH AWP
BY MANFACUTRER OR AVERAGE AT PHARMACY LOWER THAN AWP

3.1 RELY ON PI FOR MUCH OF THEIR CONTENT

3.2 AHFS PROVIDES COMPREHENSIE MONOGRAPH LINK
SUPPORTING EVIDENCE AND REFERENCES+OFF LABEL D USE SECTIN
W LINKED REFERENCES

3.3 CLININCAL PHRAMACOLOGY, FACTS AND

COMPARISONS,LEXICOMP,MICROMEDEX CONTAIN TRISSEL IV D
COMPATIBILITY,STABILITY DATA, D CLASS COMPARISONS, NATRUAL
PRODUCTS,D TABELT/CAPSULE IDENTIFICATION,INTERNATIINAL D
NAME+MOST D PRICING INCLUDE AWP BY MANFACTURER OR AT
PHARMACY
3.4 CAUTION: RPH RELY ON DATA IN DI RESOURCES BUT PI UPDATED,
LAG TIME TILL D MONOGRAPH INCLUDES UPDATE SO CHECK PI
DIRECTLY ON FDA WEBSITE DRUGDD @FDA

3.5 DRUG MONOGRAPH SITES PULL IN INFORMATION FROM PI AND

OTHER RSOURCES(TRISSELS IV INFO IN LEXICOMP,MICROMEDEX,
CLINICAL PHARMACOLOGY

3.6 GENERAL D INFORMATION RESOURCES CONTAIN MONOGRAPH

ON EACH DRUG, THE MONOGRAPH INCLUDE FDA APPROVED
INFORMATION FROM DRUGS PI, PLUS SOME OTHER ITEMS DEPEND ON
RESOURCE

3.7 paid SUBSCRIPTIONS VERSUS FREE ACCESS

3.7.1 AHFS:AHFS DI+AHFS DI ESSENTIAL :BOOK(MONOGRAPH+PT
COUNSEL), AHFS CLINICAL DI=CDI:ONLINE+MOBILE APP INCLUDED
W LEXICOMP ONLINE, AHFS DI+AHFS DI ESSENTIAL
DATABASE+REALTIME UPDATES( D SHORTAGE, FDA SAFETY ALRT)

3.7.2 CLINICAL PHARMACOLOGY

ONLINE, MOBILE APP, MONOGRAPH RX,OTC DS, NATRUAL PRODUCTS AND
INVESTIGATIONAL DS

3.7.3 DRUG INFORMATION PORTAL NLM:government no charge

ONLINE,D SEARCHES LINK TO OTHER NLM DATABASES FOR RELATED
INFORMATION, EG: DAILY MED FOR PI,LACTMED FOR EFFECT ON
BREASTFEED,PILLBOX FOR D IDENTIFICATION AND IMAGES

3.7.4 EPOCRATES/EPOCRTES PLUS

ONLINE AND MOBILE APP, FREE W REGISTRATION, DI+GUIDELINE SUMMARIES,
EPOCRATES PLUS (FEE REQQUIRED ) EXPAND INTO EVIDENCE BASED DISEASE
MANAGEMENT+NATRUAL PRODUCT, LAB AND DIAGNOSTIC INFOMRATION+ICD-10
CODING FOR BILLING PURPOSES

3.7.5 FACTS AND COMPARISONS

D FACTS AND COMPARISON: BOOK, FACTS AND COMPARISONS EANSWERS: ONLINE,
MONOGRAPH OF RX, OTC DS ORGANIZED BY THERAPEUTIC CLASS, D MONOGRAPH,
COMPARTIVE D CHARTS, UNIQUE RESOURCES(SEARCH DS BASED ON ADVERSE RX)

3.7.6 LEXICOMP
D INFORMATION HANDBOOK:BOOK, LEXI-DRUGS:ONLINE AND MOBILE APP,
INCLUDED W UP TO DATE, D MONOGRAPH ORGANIZED ALPHABETICALLY
+APPENDICES( D CLASS COMPARISONS, EQUIVALENT DOSING CHARTS),MUTIPLE
CLINICAL DATABASES(BEYOND LEXI DS)DEPEND ON LEVEL PURCHASED

3.7.7 MICROMEDEX
DRUGDEX: ONLINE AND MOBILE APP, MUTIPLE CLININCAL DATABASES BEYOND
DRUGDEX

3.7.8 PRESCRIBERS DIGITAL REFERNCE( MOBILE PDR)

MOBILE APP, FREE W REGISTERATION, PREVIOUSLY PHYSICIAN DESK REFERENCE,
INCLUDES INFORMATION FOR DS, VACCINES, BIOLOGICS, MORE DETAILED THAN
DRUG PIS+ PRACTICAL INFORMATION(WHERE NJECTIION GIVEN, TIME TO REACH
CLINICAL EFFECT)

3.7.9 DRUGS.COM:FREE
ONLINE AND MOBILE APP, FREE FOR PROFESSIONALS , CONSUMERS, D
INFORMATION FROM AHFS D INFORMATION, MICROMEDEX, FACTS AND
COMPARISONS AND FDA

3.7.10RXLIST:FREE
ONLINE AND MOBILE APP, FREE FOR PROFESSIONALS AND CONSUMERS, D
INFORMATION SOURCED FROM OTHER PRODUCTS :FDA, CERNER MUTUM AND
FIRST DATABANK
3.8 UNIQUE FEATURES OF COMMON D INFORAMTIO RESOURCES

3.8.1 AHFS/AHFS CDI:OFF LABEL USES, IV D COMPATIBILITY (AHFS

DI), INTERNATIONAL D NAMES(VIA USP DICTIONARY OF USAN AND
INTERNATIONAL DRUG NAMES)
3.8.2 CLINICAL PHARMACOLOGY: IV D COMPATIBILITY (VIA
TRISSELS),D PILL/PILL IDENTIFICATION, NATRUAL PRIDUCTS, D
CLASS COMPARISONS, PRICING, INTERNATIONAL D NAMES(VIA
INDEX NOMINUM)

3.8.3 DRUGS.COM: OFF LABEL USES, D/PILL IDENTIFICATION,

NATRUAL PRODUCTS, PRICING, INTERNATIONAL D NAMES

3.8.4 EPOCRATES/EPOCRATES LUS: OF LABEL USES, D/PILL

IDENTIFCATION, NATRUAL PRODUCTS(EPOCRTAES PLUS), D CLASS
COMPARISON,PRICNG

3.8.5 FACTS&COMPARISONS E ANSWERS: OFF LLABEL USE, IV D

COMPATIBILITY(VIA TRISSELS), D /PILL IDENTIFCATION, NATRUAL
PRODUCTS, D CLASS COMPARISONS, INTERNATIONAL D NAMES(VIA
MARTINDALE)

3.8.6 LEXICOMP:OFF LABEL USES, IV D COMPATABILITY( VIA

TRISSELS), D PILL/IDENTIFICATION( LEXI DS ID), NATRUAL
PRODUCTS(LEXI NATRUAL PRODUCTS), D CLASS COMPARISON(VIA
FACTS AND COMPARISONS), PRICING, INTERNATOINAL D NAMES(VIA
MARTINDALE)
3.8.7 MICROMEDEX: OFF LABEL USES, IV D COMPATIBILITY( VIA
TRISSELS), D PILL IDENTIFICATION(IDENTIDEX), NATRUAL
PRODUCTS( ALTMEDDEX),D CLASS COMPARISON, PRICING(RED
BOOK), INTERNATIONAL D NAMES(VIA MARTINDALE, INDEX
NOMINUM AND OTHERS)
3.8.8 MOBILE PDR: D PILL IDENTIFCATION, D CLASS COMPARISONS

3.8.9 OFF LABEL USE: AHFS/AHFS CDI, DRUGS.COM,

EPOCRATES/EPOCRATES PLUS,FACTS AND COMPARISONS E
ANSWERS, LEXICOMP,MICROMEDEX,2-FOR IV D COMPATIBILITY:
AHFS/AHFS CDI(IN AHFS CDI), CLININCAL PHARMACOLOGY, FACTS
AND COMPARISONS E ANSWERS,LEXICOMP,MICROMEDEX ALL 4 (VIA
TRISSELS) , 3-D PILL/IDENTIFICATION(CLINICAL PHARMACOLOGY,
DRUGS.COM,EPOCRATES/EPOCRATES/PLUS,FACTS AND
COMPARISONS EANSWERS, LEXICOMP(LEXIDRUGS ID),
MICROMEDEX(IDENTIDEX),MOBILE PDR, 4-NATRUAL
PRODUCTS(CLINICAL
PHARMACOLOGY,DRUGS.COM,EPOCRATES/EPO PLUS(EPOCRATES
PLUS),FACTS AND COMAPRISONS, LEXICOMP(LEXI NATRUAL
PRODUCTS), MICROMEDEX(ALTMEDEX), 5-D CLASS COMPAERISON(
CLICNCAL PHRMACOLOGY,EPOCRTAES/EPOCRTAES PLUS),FACTS
AND COMPARISONS EANSWERS,LEXICOMP(VIA FACT AND
CMPARISON),MICROMEDEX,MOBILE PDR, 6-PRICING(CLINICAL
PHRAMACOLOGY, DRUGS.COM,EPOCRATES/EPOCRTAES
PLUS),LEXICOMP,MICROMEDEX(RED BOOK), 7-INTERNATIONAL D
NAMES:AHFS/AHFS CDI(VIA USP DICTIONARY OF USAN AND
INTERNATIONAL D NAMES0, CLINICAL PHARMACOLGY(VIA INDEX
NOMINUM), DRUGS.COM, FACTS AND COMPARISONEANSWERS(VIA
MARTINDALE),LEXICOMP(VIA MARTINDALE),MICRMEDEX( VIA
MARTINDALE,INDEX NOMINUM )
LEXICOMP INCLUDE MONOGRAPH AND IMMUNIZATION SCHEDULE FOR
VACCINE+LINK TO IMMUNIZATION RESOURCE ON CDC WEBSITE

3.9 THE PHARMACISTS LETTER

3.9.1 NOT TRADITIONAL D MONOGRAPHS, BUT VALUBALE
RESOURCE EVIDENCE BASED DRUG INFORMATION, SAME
COMPANYY PROVIDES SIMILAR PRODUCT FOR PRESCRIBERS
CALLED THE PRESCRIBERS LETTER, SUBSCRIBERS RECEIVE
MONTHLY NEWSLETTER IN MAIL, ONLINE ACCESS
3.9.2 NEW DRUG APPROVALS, DRUG WTHDRAWAL, NEW DOSAGE
FORMS AND FIRST TIME GENERICS
3.9.3 CHARTS( EG: D CLASS COMPARISONS, DISEASE STATE TT
SUMMARIES)
3.9.4 LISTS OF MEDICATIONS W MEDGUIDES, W LINKS TO MEDGUIDE
ON FDA WEBSITE

3.9.5 PT EDUCATION SUMMARIES AND PT FLYERS

3.9.6 CONTINUNING EDUCATION CE

3.9.7 TRAINING MATERIALS FOR TECHNICANS AND INTERN

PHARMACISTS
3.9.8 FORUM FOR PEER DISCUUSIONS AND COMMENTS

4 OTC DRUG INFORMATION

4.1 OTC OR NONPRESCRIPTION DS ARE CONSIDERED SAFE AND

EFFECTIVE FOR #SELF DIAGNOSED CONDITIONS BY #GENERAL
PUBLIC, # HAVE ADEQUATE WRITTEN DIRECTIONS FOR SELF USE, # DO
NOT REQUIRE PHYSICIAN SUPERVISION, NO RX REQUIRED FOR
PURCHASE OF OTC PRODUCTS
4.2 LABELING REQUIREMENTS FOR OTC DS
4.2.1 FOR PTS, LABELING ON PACKAGE OF OTC D IN #D FACTS
PANEL(ACTIVE INGREDIENTS, USES, WARNING NOT USE DS (KIDNEY
DISEASE), SE, INACTIVE INGREDIENT)

4.3 OTC D APPROVAL MARKET

4.3.1 NEW DRUG APPLICATION NDA PROCESS: NDA FOR RX DS
THROUGH CDER, FOR OTC GO THROUGH SAME APROVAL PROCESS
OR MANFACTURE OPT STICK TO STDS IN #OTC MONOGRAPH FOR
DRUG CLASS( INGREDIENTS, DOSES, FOMULATIONS, LABELING,
STUDY DATA ON D SAFETY AND EFFECTIVENESS)

4.3.2 OTC MONOGRAPH PROCESS

4.4 LOCATING OTC DS STATUS AND LABELING

4.4.1 OTC DS HAVE GONE THROUGH NDA APPROVAL PROCESS
BECOME #FDA APPROVED DS, LISTED IN #GENERAL D INFORMATION
RESOURCES(LEXICOMP,MICROMEDEX)
4.4.2 OTC LABELING FOUND IN #SAME LOCATION ON FDA WEBSITE
CONTAINS #LABELING (PACKAGE INSERT) FOR RX DS:DRUGS@FDA,
#LABELING FOR OTC DS DOES NOT NEED TO BE SEPARATE
DOCUMENT BUT CAN BE #CONTAINER ITSELF
5 SELECT COLOR D REFERENCE

5.1 FDA ORANGE BOOK, DETERMINE IF GENERIC SUBSTITUTION OF

BRANDED PRODUCT IS #ACCEPTABE ON #AB RATING, INDICATES
#THERPEUTIC EQUIVALENCE
5.2 COLOR D REFERENCES
5.2.1 ORANGE BOOK FDA:DS INTERCHANGED W GENERICS BASED
ON THERAPEUTIC EQUIVLENCE

5.2.2 PINK BOOK CDC: INFORMATION ON EPIDEMIOLOGY AND

VACCINE PREVENTABLE DISEASE

5.2.3 PINK SHEET PHARMA INTELLIGECE:NEW REPORTS ON

REGULATORY,LEGISLATIVE, LEGAL AND BUSINESS DEVELOPMENT

5.2.4 PURPLE BOOK FDA: LIST OF BIOLOGICAL D PRODUCTS,

INCLUDING BIOSIMILARS
5.2.5 RED BOOK, PHARMACY: D PRICING INFORMATION

5.2.6 RED BOOK , PEDIATRCS AAP: SUMMAIES OF PEDIATRIC

INFECTIOUS DISEASES, ANTIMICROBIAL TT AND VACCINATIONS

5.2.7 YELLOW BOOK CDC: INFORMATION ON HEALTH RISK OF

INTERNATIONAL TRAVEL, REQUIRED VACCINES AND PROPHYLAXIS
MED
5.2.8 GREEN BOOK FDA: APROVED ANIMAL D PRODUCTS

6 LOCATING CLINICAL STUDY DATA AND RESERACH SUMMARIES

6.1 PUBMED: ACCESS MEDLINE(JOURNAL ARTICLES)+FREE SERVICE

FROM NLM

6.2 COCHRANE LIBRARY: #EVIDENCE BASED INFORMATION TO

GUIDE # CLINICAL DECISIOIN MAKING, DATA BASE OF COCHRANE #
SYSTEMIC REVIEWS CONTAIN >7500 REVIEWS, SUPPORTED BY
GOVERNMENT FUNDS AND DONATIONS, WITH NO COST ACCESS FOR
USERS, AVAILABLE AT WWW.COCHRANELIBRRAY.COM
7 CONSUMER RESOURCES

7.1 1-DRUGS.COM

7.2 2-RXLIST(SAME INFORMATION+INFORMATION ON DISEASE

STATES)
7.2.1 BOTH 1, 2:D MONOGRAPH+INFORMATION IN GDI, HAVE PT
LEVEL MATERIAL ON NATRUAL PRODUCT, #INTERNATIONAL DS, D
USE IN PREGNANCY AND BREASTFEEDING, # PILL IDENTIFIERS AND
#DRUG INTERACTION

7.3 3-CDC(WWW.CDC.GOV): INFORMATION ON INFECTIOUS DISEASES,

IMMUNIZATIONS, TRAVELERS HEALTH AND HAS SYMPTOM CHECKER

7.4 4-FDA FOR CONSUMERS; COMPREHENSIVE INFORMATION ON D

RECALLS, FOOD PRODUCTS, MEDICAL DEVICES, VACCINES, TOBACCO
PRODUCTS , CONTENT SELECTED BY AUDIENCE TYPE(WOMEN,
CHILDREN, MINORITY HEALTH)

7.5 5- US DEPARTMENT OF HEALTH AND HUMANS ERVICES WEBSITE

HEALTHFINDER.GOV: HEALTHY LIVING

7.6 6-#MAYO CLINIC (WWW.MAYOCLINIC.ORG) COMPREHENSIVE PT

INFORMATION FOR DISEASE, SYMPTOMS, TESTS AND PROCEDURES,
AND DRUGS AND SUPPLEMENTS
7.7 7- #MEDLINE PLUS(MEDLINEPLUS.GOV/FROM #NLM): HEALTH
TOPICS, DS, SUPPLEMENTS, HEALTH RELATED VIDEOS, LAB TESTS,
MEDICAL ENCYCLOPEDIA W IMAGES

7.8 8-SAFE MEDICATOINS(WWW.SAFEMEDICATION.COM FROM

ASHP): MEDICATION TIPS AND TOOLS AND SEARCHABLE DATABASE
FOR PT FOCUSED D MONOGRAPH, PULLED FORM AHFS

7.9 9-#WEBMED(WWW.WEBMD.COM): COVER DISEASES, HEALTHY

LIVING, PREGNANCY, RX AND OTC D INFORMATIO, PLUS# PILL
IDENTIFIER AND # INTERACTION CHECKER