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Cite as: K. M. White et al.

, Science
10.1126/science.abf4058 (2021).

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Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein
eEF1A
Kris M. White, Romel Rosales, Soner Yildiz, Thomas Kehrer, Lisa Miorin, Elena Moreno, Sonia Jangra, Melissa B. Uccellini, Raveen
Rathnasinghe, Lynda Coughlan, Carles Martinez-Romero, Jyoti Batra, Ajda Rojc, Mehdi Bouhaddou, Jacqueline M. Fabius, Kirsten
Obernier, Marion Dejosez, María José Guillén, Alejandro Losada, Pablo Avilés, Michael Schotsaert, Thomas Zwaka, Marco
Vignuzzi, Kevan M. Shokat, Nevan J. Krogan and Adolfo García-Sastre

published online January 25, 2021

Downloaded from http://science.sciencemag.org/ on January 26, 2021


ARTICLE TOOLS http://science.sciencemag.org/content/early/2021/01/22/science.abf4058

SUPPLEMENTARY http://science.sciencemag.org/content/suppl/2021/01/22/science.abf4058.DC1
MATERIALS

REFERENCES This article cites 58 articles, 15 of which you can access for free
http://science.sciencemag.org/content/early/2021/01/22/science.abf4058#BIBL

PERMISSIONS http://www.sciencemag.org/help/reprints-and-permissions

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Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science.
No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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