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3 0 min u t e s b e fo re b re a kfa s t a n d d in n e r fo r 1 5 d a ys , t h e n o n ly in t h e mo rn in g fo r
a n o t h e r 3 0 d a ys , ma kin g s u re t h a t t h e p a t ie n t a s s u me s a ll t h e p o s it io n s (p ro n e ,
s u p in e a n d la t e ra l) s o t h a t co n t a ct w it h t h e s a lt s is a ch ie ve d w it h a ll t h e mu cu s o f t h e
o rg a n .
It ma y h a p p e n s o me t ime s t h a t t h e d o u b le d a ily d o s a g e ca u s e s d ia rrh e a d is ch a rg e , b u t
s u s p e n d in g t h e e ve n in g d o s e s h o u ld b e a b le t o s o lve t h e p ro b le m.
Ge n e ra lly t h e b lo o d in t h e fe ce s d is a p p e a rs a ft e r five t o 1 0 d a ys , d ig e s t io n b e g in s t o
n o rma liz e a n d t h e fe e lin g o f h e a vin e s s t e n d s t o re g re s s w it h t h e re s u lt t h a t t h e
p a t ie n t ma n a g e s t o g a in w e ig h t .
E ve ryt h in g is fa irly s imp le , t h e re fo re , w h e n t h e n e o p la s ia – e ve n o f la rg e d ime n s io n s –
re ma in s co n fin e d t o t h e s t o ma ch w a ll a n d t o s o me p e rip h e ra l lymp h o n o id s .
In ca s e s w h e re t h e re is a vis ib le s p re a d in g in t h e a d ja ce n t s t ru ct u re s – e s p e cia lly in
t h e lig a me n t s – s t o ma ch ca n ce r, a s it is imp o s s ib le t o re a ch co mp le t e ly, b e co me s
e xt re me ly d ifficu lt t o u p ro o t .
Th e co lo n ie s , in fa ct , a re n o t t o u ch e d b y t h e b ica rb o n a t e a d min is t e re d in t h e s t o ma ch
a n d w o rk a s a re ce p t a cle fo r a mo re ma rke d p ro life ra t io n w h e re t h e y ca n n o t b e
a t t a cke d .
Th e y b e co me t h e re fe re n ce p o s it io n fo r a ll t h e o t h e rs , s u s t a in e d in t h e fig h t fo r
s u rviva l b y t h o s e e le me n t s o f b io ch e mica l s o lid a rit y t h a t a re a t t h e b a s is o f t h e
fo rma t io n a n d o f t h e p ro g re s s io n o f t h e ma s s e s .
To b e t t e r u n d e rs t a n d t h is co n ce p t , o n e ca n ima g in e a g re a t s p id e r w e b fo rme d b y
vo lu min o u s a g g re g a t e s in t h e co rn e rs , a n d e le me n t s o f lin e a r co n n e ct io n t h a t jo in
t h e m a n d t h a t w o rk a s co mmu n ica t io n me a n s b e t w e e n t h e ce lls . W h e n a n e le me n t , a n
a g g re g a t io n o r a g re a t p a rt o f t h e s t ru ct u re is a t t a cke d , t h e a la rm s ig n a ls mo ve fro m
t h e mo re e xp o s e d co lo n ie s t o t h o s e w h ich re ma in o u t s id e o f t h e fie ld o f a n y t o xic
s u b s t a n ce s o t h a t t h e ir d e fe n s e re a ct io n s ca n b e a ct iva t e d a n d in cre a s e d w it h o u t
limit a t io n . Fu rt h e rmo re , a d is p la ce me n t o f n u cle a r e le me n t s fro m e a ch ce ll t o w a rd s a
n o n -e n d a n g e re d lo ca t io n t a ke s p la ce t h ro u g h t h e p o ro u s ce llu la r n e t w o rk, w it h t h e
re s u lt t h a t a g re a t e r co n ce n t ra t io n o f n o b le re p ro d u ct ive s t ru ct u re s ca n w o rk
u n d is t u rb e d , e ve n h a vin g t h e t ime t o p e rfo rm g e n e t ic ch a n g e s a s a fu n ct io n o f t h e
n o xio u s a g e n t .
It is in t h is w a y t h a t a ll fo rms o f re s is t a n ce t o d ru g s a n d t o o t h e r co mp o u n d s (in clu d in g
b ica rb o n a t e ) is d e ve lo p e d , e ve n t h o u g h w h e n it co me s t o t h e la t t e r t h e a d a p t a t io n is
t o b e co n ce ive d in t e rms o f re s is t a n ce t o t h e lo w d o s a g e u s e d in t h e t h e ra p y.
Th e b io lo g ica l re a ct ive n e t w o rk t h e re fo re e xp la in s t h e p h e n o me n a o f co mmu n ica t io n
a n d d e fe n s e b e t w e e n t h e a g g re g a t e s , ce lls a n d s p o re s t h a t a re e ve n q u it e d is t a n t
fro m e a ch o t h e r. It a ls o e xp la in s t h e me ch a n is m o f t h e me t a s t a s e s , w h ich a re n o t h in g
b u t n e w fu n g in ma s s e s t h a t h a ve co lo n iz e d a n o rg a n a ft e r d e p a rt in g a n d b e in g fe d b y
t h e mo t h e r co lo n y.
As s u min g , h o w e ve r, t h a t t h e s p id e r w e b is w id e s p re a d a n d t h a t it t o u ch e s ma n y
o rg a n s , o n e ca n a s k w h y me t a s t a s e s a re p ro d u ce d g ra d u a lly, firs t in o n e o rg a n a n d
t h e n in a n o t h e r, a n d s o o n . Th e e xp la n a t io n co n s is t s in t h e fa ct t h a t , a s lo n g a s a
t is s u e h a s in t e g rit y a n d t o n e – t h a t is , it is re a ct ive – n o fu n g in ro o t in g is p o s s ib le .

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d is e a s e b e yo n d a ce rt a in limit it b e co me s mo re s u s ce p t ib le t o a t t a ck a n d t h u s it ca n b e
co lo n iz e d . Th is is t h e re a s o n w h y t h e ma in ca u s e s o f me t a s t a s is a re o ft e n t h e o fficia l
t h e ra p ie s , a s t h e y p ro d u ce s u ch t is s u e s u ffe rin g a s t o re n d e r t h o s e t is s u e s
d e fe n s e le s s t o t h e fu n g i.
Go in g b a ck t o t h e s t o ma ch ca n ce r, t h e p o in t s t h a t a re le s s a cce s s ib le fo r t h e t h e ra p y
w it h b ica rb o n a t e a re t h e lig a me n t s , s t a rt in g p o in t s fo r t h e d e fe n s e a n d t h e
re g e n e ra t io n o f t h e co lo n ie s . If, b e s id e s t h e lig a me n t s t h e re is a ls o a n in vo lve me n t o f
o t h e r o rg a n s , e s p e cia lly t h e live r, it a ll b e co me s e ve n mo re d ifficu lt .
It is t h e re fo re a p p ro p ria t e t o t re a t t h e s t o ma ch t u mo r a s s o o n a s p o s s ib le a n d w it h
t h e g re a t e s t p o s s ib le in t e n s it y in o rd e r t o u p ro o t it co mp le t e ly a n d o n ce a n d fo r a ll
b e fo re it is a b le t o g e t it s e lf “ o rg a n iz e d ” . Th e p o s it io n in g o f a ca t h e t e r in a p e rig a s t ric
lo ca t io n a n d a n a rt e ria l o n e in t h e ce lia c t rip o d t h ro u g h w h ich it is p o s s ib le t o
a d min is t e r t h e b ica rb o n a t e d ire ct ly o n t o t h e fu n g in ma s s e s ca n a llo w t h e re g re s s io n o f
t h e d is e a s e e ve n in co mp le x ca s e s .
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