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  • Antibiotics - Compleate Classification

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    Neal Gupta
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    The document classifies anti-microbial drugs according to their mechanism of action in 7 categories: 1) Those that inhibit cell wall synthesis like penicillin and cephalosporins. 2) Those that cause leakage from the cell membrane like polymyxines and colistin. 3) Those that inhibit protein synthesis like tetracycline. 4) Those that cause misreading of RNA and affect permeability like aminoglycosides and streptomycin. 5) Those that inhibit DNA gyrase like fluoroquinolones. 6) Those that interfere with DNA function like rifampin and metronidazole. 7) Those that interfere with DNA synthesis like acyclovir and zidovudine.

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    pharmacology note

    Original Title

    Antibiotics- Compleate Classification

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    The document classifies anti-microbial drugs according to their mechanism of action in 7 categories: 1) Those that inhibit cell wall synthesis like penicillin and cephalosporins. 2) Those that cause leakage from the cell membrane like polymyxines and colistin. 3) Those that inhibit protein synthesis like tetracycline. 4) Those that cause misreading of RNA and affect permeability like aminoglycosides and streptomycin. 5) Those that inhibit DNA gyrase like fluoroquinolones. 6) Those that interfere with DNA function like rifampin and metronidazole. 7) Those that interfere with DNA synthesis like acyclovir and zidovudine.

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    © All Rights Reserved
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    6K views2 pages

    Antibiotics - Compleate Classification

    Uploaded by

    Neal Gupta
    The document classifies anti-microbial drugs according to their mechanism of action in 7 categories: 1) Those that inhibit cell wall synthesis like penicillin and cephalosporins. 2) Those that cause leakage from the cell membrane like polymyxines and colistin. 3) Those that inhibit protein synthesis like tetracycline. 4) Those that cause misreading of RNA and affect permeability like aminoglycosides and streptomycin. 5) Those that inhibit DNA gyrase like fluoroquinolones. 6) Those that interfere with DNA function like rifampin and metronidazole. 7) Those that interfere with DNA synthesis like acyclovir and zidovudine.

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    of 2

    Anti Microbial Drugs

    Classification According to Mechanism of Action


    Classification Reference- KD Tripathi (Pharmacology)

    Inhibit Cause Leakage Inhibit Cause misreading or Inhibit Interfere with Interfere with
    Cell wall synthesis From cell membrane Protein Synthesis RNA and affect DNA gyrase DNA function DNA synthesis
    permeability
    Penicillin Polymyxines
    Tetracycline Aminoglycosides Fluoroquinolones Rifampin Acyclovir
    Cephalosporins Colistin Streptomycin Ciprofloxacin etc Metronidazole Zidovudine
    Gentamycin
    Nystatin Cloramphenicol
    Cycloserine
    Sulfonamides, PAS, Sulfones, Interfere with
    Trimethoprim, Ethambutol,
    Erythromycin Intermediary Metabolism
    Bacitracin polymers
    Bacitracin Amphotericin- B
    Clindamycin

    Vancomycin Hamycin Linezolid

    www.facebook.com/pharmavideo/

    Note- Mnemonics are based on my thoughts; it may or may


    not useful to you. It’s always better to create your own so you
    may memorize it.

    E Mail- solutionpharmacy@gmail.com &


    Reach solution at- www.facebook.com/pharmavideo/ E Mail- solutionpharmacy@gmail.com & Reach solution at- www.facebook.com/pharmavideo/
    Anti Microbial Drugs
    Classification According to Various Parameters
    Classification Reference- KD Tripathi (Pharmacology)

    Types of Organism
    Against which primarily
    Spectrum of Activity Type of Activity
    Active

    Antibacterial Bacteriostatic Bacteriosidal


    Penicillins, Aminoglycosides
    Erythromycin etc Narrow Broad
    Spectrum Spectrum Sulfonamide Penicillin
    Antifungal
    Griseofulvin, Amphotericin B, Aminoglycosides
    Penicillin G Tetracycline Tetracycline
    Ketoconazole etc
    Polypeptides
    Chloramphenicol
    Antiviral Streptomycin Chloramphenicol
    Acyclovir, Amantadine,
    Erythromycin Rifampin
    Zidovudine etc Erythromycin
    Isoniazide
    Ethambutol
    Antiprotozoal
    Chloroquine, Pyrimethamine, Pyrazinamide
    Metronidazole, Diloxanide etc Linezolid
    Cephalosporin
    Anthalmentic
    Mebendazole, Pyrantel, Vancomycin
    Niclosamide, Diethyl
    carbamazine etc Nalidixic Acid

    Ciprofloxacin

    Metronidazole

    Cotrimoxazole

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