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Performance Assessment: Title Theme Sub-Theme Standard Assessed Outcome(s)
Performance Assessment: Title Theme Sub-Theme Standard Assessed Outcome(s)
Performance Assessment: Title Theme Sub-Theme Standard Assessed Outcome(s)
a) For a lytic cycle to reproduce a new phage: The virus attaches itself to its host to insert
its genome into the cell, the DNA replicates which than synthesizes new DNA and
proteins, new phages assemble and exit the damaged host cell.
b) ) The major determinant whether the virus exhibits a lytic or a lysogenic cycle is its
genome nature. If the virus is naturally hazardous, it is usually undergoing the lytic
process to reproduce itself, but if it is less dangerous then it performs lysogenic cycle.
Sometimes in lysogenic cycles, if a virus is exposed to external factors such as UV light
or stressors, it can actually extract themselves from the host genome and enter the lytic
cycle. Note that a virus can only switch itself from lysogenic to lytic cycle, and never
from lytic to lysogenic.
c) The risks are less extreme that the lytic-cycle viruses. The lytic cycle infiltrates a cell and
immediately kills the host by producing more of itself in the process, but for lysogenic
cycle, it is still harmful but just slower than the lytic process. That does not
underestimate its dangerous effects, the risk of lysogenic cycles is that the more time it
utilizes, the more infected daughter cells are produced in the host.
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism.
Viruses infect all types of life forms, from animals and plants to microorganisms,
including bacteria and archaea. Viruses are considered by some biologists to be a life form, because
they carry genetic material, reproduce, and evolve through natural selection, although they lack the
key characteristics, such as cell structure, that are generally considered necessary criteria for life.
Because they possess some but not all such qualities, viruses have been described as "organisms
at the edge of life”, and as self-replicators.
Research ANY three viruses of plants, animals, or humans. Collect the data regarding host, rate of
infection and rate of spread. Mention the reference (scientists name, publication). Present your
findings below:
1. Tobacco mosaic virus (TMV): plants serve as its host. Its symptoms include stunting,
malformation of leaven, yellow streaking of leaves. It is usually known to carry out the lytic
cycle, where the rate of infection is fast and direct. This virus is easily transmitted when an
infected leaf rub against another. Dmitry Ivanovsky is a microbiologist who discovered this
virus in 1887 to 1890.
2. Hepatitis B: only humans are affected by this virus. A person that is infected with
Hepatitis B will experience fever, fatigue, nausea. The spread might be slow, but it can
possibly spread through body fluid contact blood, sharing needles or syringes, or saliva.
Hepatitis B uses the lysogenic process for reproduction; thus, it is slow in showing symptoms
of infection, but still poses a great threat to the person when the time comes. This virus was
discovered by Dr. Baruch Blumberg in 1965.
3. Rabies: usually infects animals, but rarely in humans. An animal that is suffering from
rabies will show symptoms such as vomiting, hyperactivity, headache. This virus mainly
reproduces new phages through the lytic process, so the infection rate is fast, which
causes the symptoms to show pretty quick. This virus can be transmitted rapidly if the
animals have a direct contact with each other, such as scratches, broken skin, or mucous
membranes in the eyes or nose. Georg Gottfried Zinke and Franz Christian Karl Krugelstein
worked to together to officially announce this virus and its dangers.
What would happen with a sickness like varicella (chickenpox)- it is very contagious, but usually not
dangerous and will go away in about 10 days. Once you get it, you are immune to it, and it is not
likely you will ever get it again.
a. What parameters would you set in this applet to model this disease?
b. Write your own hypothesis.
c. Test your hypothesis using the model. Record your results. Were they what you
expected? Why or why not?
a)
I put 90% sick rate since the disease is very contagious and spreads fast. I set
the recovery rate in moderate because the person can recover in about 10
days. Because the infected person will get immune to it after being sick in 10
days, I set the susceptibility and days to susceptibility fairly low.
b) My hypothesis is that at first the rate of sick people will be high in the initial
days of the disease infection. A lot will be susceptible to this disease at first,
but in about 10 days, the population of the infected people will decrease in
its rate, because of the immunity that people gain after getting the disease,
lowering the susceptibility of the population.
c)
Research the effect of Covid-19 till date in terms of the mortality rate and the survival rate. Also explain the effect of
covid-19 on different geographical parts of the world. Research that the increase or decrease rate of infection is because of
any environmental conditions. If Yes what are they?
Mortality rates: Ever since the pandemic arose, the mortality rates increased non-stop all around the globe. Studies call
these as “excess deaths” which refer to the increase in mortality in the absence of Covid-19. Researchers not only record the
infected rates of the Covid-19 but also all the victims that fell into the social and economic negative impacts that the disease
has caused. Studies has revealed that the vital registration data sourced from death certificates on cause of death are likely to
underestimate the mortality burden associated with the disease for several reasons behind:
- some deaths may be assigned to other causes of death due to the absence of widespread testing and low rates of disganoses
at the time of death
- covid-19 deaths do not take into account the indirect consequences of the pandemic of mortality levels, such as the rapid
reduction in access to and use of health care services and psychosocial consequences of stay-at-home orders.
- several other psychological effects of the pandemic, such as stress and depression, all lead to an increase in suicidal and
overdose deaths.
- as well as economic hardships, housing and food insecurity.
As a result, the increase rate of mortality rate caused can be linked to the COVID-19 pandemic.
Though, the deaths attributed to the COVID-19 mask the deaths that do not take in account of the disease:
“Overall, we found that for every 100 deaths assigned to Covid-19, 144 all-cause deaths occurred (95% CI, 130 to 159),
implying that 31% (95% CI, 24% to 38%) of excess deaths were ascribed to causes of death other than Covid-19 itself.”
Survival rates: The COVID-19 mortality rate has dropped in recent times. Although the reason of the survival rates aren’t
very clear, experts have managed to point out the contributing factors, which includes a higher proportion of cases among the
young, increased knowledge of treatments, improved therapies, and less overcrowding in hospitals.
"It's going to be a long road," Petrilli added. "While it's good news that the mortality rate is down, the reason that it is down
is because everyone is doing a good job with mask-wearing and distancing. We just need to keep it up."
Geographic relations: Virus transmission can be influenced by a lot of geographic factors, that includes;
- climatic conditions: researchers found that the severity of the outbreak is more observed in mid-latitude regions, where the
temperatures are considerably low.
- population factors: population migration, immunity power, age groups, all play a major role in the transmission of the
disease.
- economic status: reasons such as reduction in trade and tourism had lead a country to a poor economic status, which makes
it difficult for a country to provide not only enough supplies but also other basic provision for survival.
Question # 2 4 6 Score
Parts a, b, c Student explained Student explained Students explained
the steps of the cycle the steps of the the steps of the cycle
properly. cycle properly and properly, able to
was able to explain explain the nature of
the nature of the the virus in addition to
virus. the effect of
lysogenic phage on
the host genome.
2 4 6
Explore Students researched Students researched Students researched
one virus (ANY plant, two viruses (ANY three viruses (ANY
animal based) along plant, animal plant, animal based)
with host, rate of based) along with along with host, rate
infection, rate of host, rate of of infection, rate of
spread with infection, rate of spread with reference
reference to any spread with to any publication.
publication. reference to any
publication.
0.5 1 2
Interpretation Students are able to Students are able to Students are able to
set the parameters to set the parameters set the parameters to
model the given to model the given model the given
disease. disease and are also disease, are also able
able to make a to make a hypothesis
hypothesis. in addition to record
the result and suggest
that suggested
hypothesis was
correct or incorrect.
2 3 6
Research and Students are able to Students are able to The answers
collaborate explain the mortality explain the mortality contained required
rate and the survival rate and the survival items i.e., mortality
rate because of rate because of rate and the survival
Covid-19 till date. Covid-19 till date rate because of
and effect of covid- Covid-19 till date and
19 on different effect of covid-19 on
geographical parts different
of the world geographical parts of
the world and also the
increase or decrease
rate of infection
because of any
environmental
conditions (IF ANY).