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NHSCT/18/1204 Anaemia and Vitamin Supplementation in Pregnancy
NHSCT/18/1204 Anaemia and Vitamin Supplementation in Pregnancy
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Reference No: NHSCT/18/1204
Title: Anaemia and Vitamin Supplementation in Pregnancy
Key words within Anaemia, Haemoglobin, iron, ferritin, pregnancy
policy (max 10 words):
Policy Author(s): Louisa Lapworth, Deputy Sister OPD4
Cathy Hamilton, Practice Development Midwife
Responsible Director: Marie Roulston, Divisional Director of Women, Children and Families
Division
Policy Type: Trust Wide ☐ Division Specific ☒ Clinical and/or social care ☒
Policy Replacement: Yes ☒ No ☐ Anaemia and Vitamin Supplementation in
Pregnancy - NHSCT/14/755
Directors/Divisions Nursing ☐
policy to be issued to: Medicine ☐
Finance ☐
Medicine and Emergency Medicine ☐
Human Resources, Organisational Development and Corporate
Communications ☐
Community Care ☐
Surgical and Clinical Services ☐
Mental Health, Learning Disability and Community Wellbeing ☐
Women, Children and Families ☒
Strategic Development and Business Services ☐
Target Audience, ie, This guideline is directed to midwives, obstetricians and other staff
specific staff groups working with pregnant women in both the hospital and community
setting.
Approved by: Dr Kate Scott & Mrs Suzanne Pullins 4 May 2018
Co-chairs, Clinical and Social Care Policy and Appendix 4 - document
Guidelines Committee link revised, 18 Dec 2018
Operational Date: 23 May 2018 Review Date: 30 November 2020
Policy Library Clinical and Social Care - Hospital (incl Comm Hosp) ☐
Categories: Clinical and Social Care - Children’s Hospital & Community ☐
(Please tick as Clinical and Social Care - Community ☐
appropriate) Clinical and Social Care - Mental Health and/or Learning Disability ☐
Children’s Nursing ☐
Maternity & Gynae ☒ Estates ☐
Health & Safety ☐ Human Resources ☐
Palliative Care ☐ Major Incident Plan ☐
Infection Control ☐ Information Management ☐
Family Planning ☐ Allied Health Professions ☐
Finance ☐ Trust Wide ☐
Safeguarding Children ☐
NHSCT Vision
To deliver excellent integrated services in partnership with our community.
Contents
2.0 Responsibilities 3
Intrapartum management 8
Postnatal management 8
4.0 Monitoring 13
2.0 Responsibilities
Line managers are responsible for ensuring that staff have a working
knowledge of and adhere to the guidance and that any amendments are
disseminated.
All practitioners are responsible for familiarising themselves with and adhering
to this guidance.
During the antenatal period all women should be given written dietary
information to maximise iron intake and absorption 2.
Letter to woman informing her to collect prescription from General Practitioner (GP). Dietary a
Letter to GP requesting prescription for oral combined iron preparation such as Pregaday® 1
Hb increasing
No:
Yes & compliance good:
Check compliance; consider alternative prepa
Continue oral iron
Check ferritin levels (ochre-topped bottle and
The professional who initiates a test is responsible for ensuring that any necessary follow up actio
SQR/SAI/2017/023 (MCH & PHC)
Letter to woman with dietary advice (Appendix 4) and request to collect prescription from GP.
Letter to GP requesting prescription for oral combined iron preparation such as Pregaday® 1 da
If improving:
Continue oral iron
The professional who initiates a test is responsible for ensuring that any necessary follow up actions are
Community midwife follow-up with ferritin < 15 - consider discussion with Consultant of Week prior to re
Postnatal management
Vitamins are organic compounds essential for normal cell function, growth
and development. There are 13 essential vitamins: vitamins A, C, D, E, K and
the B series including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5
(pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folic acid), B12
(cobalamin).
Combined preparations
Pregaday® Elemental Iron 100mg Folic acid 350 micrograms
®
Fefol Elemental Iron 47mg Folic acid 500 micrograms
®
Galfer FA Elemental Iron 100mg Folic acid 350 micrograms
Pregnacare® Elemental Iron 17mg Folic acid 400 micrograms Vit. D
10 micrograms
Folic acid supplements taken before and during pregnancy can reduce the
occurrence of neural tube defects. The risk of a neural tube defect occurring
in a child should be assessed and folic acid given as follows:
Women in the high-risk group who wish to become pregnant (or who
are at risk of becoming pregnant) should be advised to take folic acid 5
4
mg daily from pre-conception and continue until week 12 of pregnancy
(women with sickle-cell disease should continue taking their normal
dose of folic acid 5 mg daily (or to increase the dose to 5 mg daily) and
continue this throughout pregnancy).
Vitamin A Supplements
Vitamin C, B and E
Vitamin C is commonly included in low doses (less than 200 mg/day) within
multivitamin preparations for pregnancy but has also been given in higher
doses (up to 1000 mg/day) as a supplement, alone or in combination with
vitamin E. Routine supplementation with higher doses of Vit. C and E are not
recommended.
The Reference Nutrient Intakes (RNI) of 10 μg/d (400 IU/d) proposed for the
general UK population (aged 4years and above) includes pregnant and
lactating women and population groups at increased risk of having a serum
25(OH)D concentration < 25 nmol/L. A separate RNI is not required for these
groups. This is a change from previous advice.7,8
From October to March everyone over the age of five, including pregnant and
breastfeeding women, should consider taking a daily supplement containing
10 micrograms of vitamin D7,8 to ensure the mother’s requirements for vitamin
D are met and to build adequate fetal stores for early infancy.
Pregnacare® once daily is the medication that contains the required Vitamin D
(10 micrograms) and folate (400 micrograms) requirement.
2. National Institute for Health and Care Excellence. CG62 Antenatal Care for
uncomplicated pregnancies.
https://www.nice.org.uk/guidance/cg62/resources/antenatal-care-for-
uncomplicated-pregnancies-pdf-975564597445
7. Public Health Authority (2016). Folic acid and Vitamin D guidelines for
health professionals http://www.publichealth.hscni.net/publications/folic-acid-
and-vitamin-d-guidelines-health-professionals
11. HSC/PHA (2017). Safety & Quality Reminder of best practice guidance.
SQR/SAI/2017/023 “Sepsis due to untreated urinary tract infections in
pregnancy.”
http://insight.hscb.hscni.net/download/safety_quality_and_learning/sqr_best_p
ractice_reminder_letters/SQR-SAI-2017-023-MCH-PHC-Sepsis-due-to-
untreated-urinary-tract-infections-in-pregnancy.pdf
This policy has been drawn up and reviewed in the light of Section 75 of the
Northern Ireland Act (1998) which requires the Trust to have due regard to the
need to promote equality of opportunity. It has been screened to identify any
adverse impact on the 9 equality categories.
The policy has been ‘screened out’ without mitigation or an alternative policy
proposed to be adopted.
This document can be made available on request on disc, larger font, Braille,
audio-cassette and in other minority languages to meet the needs of those
who are not fluent in English.
Louisa Lapworth
Cathy Hamilton 18th May 2017
Lead Policy Authors Date
Appendix 1
Ferrous Fumarate (Galfer®) comes as 210mg; 322mg and 305mg. Northern Trust
stock the:
Patients should have received an information leaflet prior to attendance. The SHO
on call overnight will calculate and prescribe the dose of Monofer ® required as per
the equation below.
- Patient’s iron need depends on Hb level and body weight (USE BOOKING
WEIGHT).
-
Use Ganzoni formula to calculate iron need and round to nearest 100mg Using
Ganzoni formula the Iron need (in mg iron) is equal to
Worked example:
Step 3: Monitoring:
The patient should be observed prior to infusion, during infusion and for at least 30
minutes following each Monofer® injection for signs and symptoms of hypersensitivity
reactions9 (Appendix 3).
NOTE
Monofer® is not licensed for use in patients under 18 years old – Ferinject ® is
available for these patients.
Caution should be advised in patients with severe asthma – use in discussion with
Consultant
2 Ampoules (200mg of Venofer) in 200mls of 0.9% Sodium Chloride (N/Saline) for every
patient on alternate days for 3 doses only.
100mls per hour for 15 minutes as test Dose. Have adrenaline® (SC), Piriton® and
Hydrocortisone available.
200mls / hour until finished
Standard dose: 1000 mg (2 X 10mls vials) in 250 mls 0.9% Sodium Chloride intravenous at
the rate of 1000ml/ hr.
No test dose required. (Low antigenic properties, thus anaphylaxis is extremely rare)
Minimum administration time: 15 minutes.
Follow up: Arrange recheck haemoglobin after 2-4 weeks of having intravenous iron.
®
Midwifery Procedure for infusion of Ferinject (by permission of Ulster Hospital,
Dundonald)
Record baseline observations; temperature, pulse and blood pressure.
Prepare infusion of Ferinject ®
Have anaphylaxis pack in clinical area
Prepare skin with a sterett
Insert Cannula and secure with a dressing
Take blood sample for FBP if requested
Flush Cannula with 2mls 0.9% Sodium Chloride
Commence infusion of Ferinject ®
Observe mother for any adverse effects
Remove Cannula after infusion complete.
Appendix 3
The following is an MHRA Drug Safety Update (Sept. 2013) following
hypersensitivity reactions to IV Iron in France)
Prescribing