CLSI eCLIPSE - Jose Ricardo Aguirre Calderón - BD - 01/23/2018. Unauthorized duplication or network sharing is not allowed.

Glossary I

Glossary I (Part 1). -Lactams: Class and Subclass Designations and Generic Name
242

M100, 28th ed.

In the late 1990s, several authorities were consulted to construct the glossary. The intention was to include all agents that appeared in M100, along
with related agents available for human use. Since that time, agents have been added to the glossary as they were introduced to CLSI, and they do not
need to be FDA cleared to be included. It cannot be assumed that the list is exhaustive, and it should be noted that some agents are no longer available
for human use.

Antimicrobial Class Antimicrobial Subclass(es) Agent(s) Included; Generic Name(s)

Penicillins Penicillinase-labile Penicillin Penicillin
penicillinsa Aminopenicillins Amoxicillin
Ampicillin
Carboxypenicillins Carbenicillin
Ticarcillin
Ureidopenicillins Azlocillin
Mezlocillin
Piperacillin
Penicillinase-stable Cloxacillin
penicillinsb Dicloxacillin
Methicillin
Nafcillin
Oxacillin
Aminopenicillin Mecillinam
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Clinical and Laboratory Standards Institute. All rights reserved.

-lactam combination agents Amoxicillin-clavulanate

Ampicillin-sulbactam
Aztreonam-avibactam
Cefepime-tazobactam (1:1)
Cefepime-zidebactam
Ceftaroline-avibactam
Ceftazidime-avibactam
Ceftolozane-tazobactam
Imipenem-relebactam
Meropenem-vaborbactam
Piperacillin-tazobactam
Ticarcillin-clavulanate
Cephems (parenteral) Cephalosporins Ic Cefazolin
Cephalothin
Cephapirin
Cephradine
Cephalosporins IIc Cefamandole

For Use With M02 and M07

Cefonicid
Cefuroxime (parenteral)
Cephalosporins IIIc Cefoperazone
Cefotaxime
Ceftazidime
Ceftizoxime
Ceftriaxone
Cephalosporins IVc Cefepime
Cefpirome
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Glossary I (Part 1). (Continued)

©

For Use With M02 and M07

Clinical and Laboratory Standards Institute. All rights reserved.

Antimicrobial Class Antimicrobial Subclass(es) Agent(s) Included; Generic Name(s)

Cephems (parenteral (Continued) Cephalosporins with anti-MRSA activity Ceftaroline
Ceftobiprole
Cephamycins Cefmetazole
Cefotetan
Cefoxitin
Oxacephem Moxalactam
Siderophore cephalosporin Cefiderocol
Cephems (oral) Cephalosporins Cefaclor
Cefadroxil
Cefdinir
Cefditoren
Cefetamet
Cefixime
Cefpodoxime
Cefprozil
Ceftibuten
Cefuroxime (oral)
Cephalexin
Cephradine
Carbacephem Loracarbef
Monobactams Aztreonam
Penems Carbapenems Biapenem
Doripenem
Ertapenem
Imipenem
Meropenem
Razupenem
Penems Faropenem
Sulopenem
Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; FDA, US Food and Drug Administration.

Footnotes

a. Hydrolyzed by staphylococcal penicillinase.

b. Not hydrolyzed by staphylococcal penicillinase.

c. Cephalosporins I, II, III, and IV are sometimes referred to as first-, second-, third-, and fourth-generation cephalosporins, respectively. Cephalosporins III and IV
are also referred to as “extended-spectrum cephalosporins.” This does not imply activity against extended-spectrum -lactamase–producing gram-negative
bacteria.

M100, 28th ed.

243

Glossary I
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Glossary I

Glossary I (Part 2). Non–-Lactams: Class and Subclass Designations and Generic Name
244

M100, 28th ed.

In the late 1990s, several authorities were consulted to construct the glossary. The intention was to include all agents that appeared in M100, along
with related agents available for human use. Since that time, agents have been added to the glossary as they were introduced to CLSI, and they do not
need to be FDA cleared to be included. It cannot be assumed that the list is exhaustive, and it should be noted that some agents are no longer available
for human use.

Antimicrobial Class Antimicrobial Subclass(es) Agent(s) Included; Generic Name(s)

Aminocyclitols Spectinomycin
Aminoglycosides Amikacin
Gentamicin
Kanamycin
Netilmicin
Plazomicin
Streptomycin
Tobramycin
Aminoglycoside-fosfomycin Amikacin-fosfomycin
Ansamycins Rifamycins Rifabutin
Rifapentine
Rifampin
Rifaximin
Folate pathway antagonists Dihydrofolate reductase inhibitors Iclaprim
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Clinical and Laboratory Standards Institute. All rights reserved.

Sulfonamides
Trimethoprim
Trimethoprim-sulfamethoxazole
Sulfonamides Sulfamethoxazole
Sulfisoxazole
Combination Trimethoprim-sulfamethoxazole
Fosfomycins Fosfomycin
Glycopeptides Glycopeptide Vancomycin
Lipoglycopeptides Dalbavancin
Oritavancin
Teicoplanin
Telavancin
Ramoplanin
Lincosamides Clindamycin
Lincomycin
Lipopeptides Daptomycin
Surotomycin

For Use With M02 and M07

Polymyxins Colistin
Polymyxin B
Macrocyclic lactone Fidaxomicin
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Glossary I (Part 2). (Continued)

©

For Use With M02 and M07

Clinical and Laboratory Standards Institute. All rights reserved.

Antimicrobial Class Antimicrobial Subclass(es) Agent(s) Included; Generic Name(s)

Macrolides Azithromycin
Clarithromycin
Dirithromycin
Erythromycin
Fluoroketolide Solithromycin
Ketolides Nafithromycin
Telithromycin
Nitroheterocyclics Nitrofuran Nitrofurantoin
Nitroimidazoles Metronidazole
Secnidazole
Tinidazole
Thiazolides Nitazoxanide
Tizoxanide
Oxazolidinones Linezolid
Tedizolid
Peptide Magainin Pexiganan
Phenicols Chloramphenicol
Thiamphenicol
Pleuromutilins Lefamulin
Retapamulin
Pseudomonic acid Mupirocin
Quinolones Cinoxacin
Garenoxacin
Nalidixic acid
Benzoquinolizine Levonadifloxacin
Fluoroquinolones Besifloxacin
Ciprofloxacin
Clinafloxacin
Delafloxacin
Enoxacin
Finafloxacin
Fleroxacin
Gatifloxacin
Gemifloxacin
Grepafloxacin
Levofloxacin
Lomefloxacin
Moxifloxacin
Norfloxacin
Ofloxacin
Pefloxacin
Sparfloxacin

M100, 28th ed.

Trovafloxacin
Ulifloxacin (prulifloxacin)
245

Glossary I
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Glossary I

Glossary I (Part 2). (Continued)

246

M100, 28th ed.

Antimicrobial Class Antimicrobial Subclass(es) Agent(s) Included; Generic Name(s)
Quinolonyl oxazolidinone Cadazolid
Steroid Fusidane Fusidic acid
Streptogramins Quinupristin-dalfopristin
Tetracyclines Doxycycline
Minocycline
Tetracycline
Fluorocycline Eravacycline
Glycylcycline Tigecycline
Aminomethylcycline Omadacycline
Triazaacenaphthylene Gepotidacin
Abbreviation: FDA, US Food and Drug Administration.
©
Clinical and Laboratory Standards Institute. All rights reserved.

For Use With M02 and M07