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UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |1

1. Which of the ff is/are parent drug/s?


i. Digitoxin
ii. Hydrocortisone
iii. Primidone
iv. Propranolol
a. I and II only d. I, III, and IV only
b. III and IV only e. AOTA
c. I, II and IV only
2. Litharge is
a. Lead carbonate c. Lead monoxide
b. Lead acetate d. Lead subacetate
 Used in cementing pipes & pharmaceutical ingredient in lead subacetate solution
3. The unit of radiation damage used in medicine
a. Rem c. Sievert
b. RBE d. Rad
 Sievert (Sv) – SI unit for the effective damage 1Sv = 100 Rem
 RBE – Relative Biological Effectiveness of the radiation
4. Most frequent impurities in talc are oxides of
a. Calcium c. Iron
b. Aluminum d. All of the above
5. Protonic concept of acidity
a. Classical concept c. Arrhenius concept
b. Lewis acid-base concept d. Bronsted Lowry concept
 Classical – acid are substance that contains Hydrogen and when dissolve in water will furnish
hydrogen ion.
 Lewis acid-base – “electrophilic” seeking electrons
6. What is the type of formula of the chemical Methoxyethane
a. RCHO c. RCOOR
b. RCOOH d. ROR
7. What is the common functional moiety present in the molecules of the clinically useful carbonic
anhydrase inhibitor
a. Benzene c. Nitrobenzene
b. CH3 d. SNO2H2
8. Which of the following opioids contain phenanthrene nucleus?
a. Morphine c. Methadone
b. Meperidine d. Fentanyl
9. Names as “acid former” by Lavoisier
a. Hydrogen c. Nitrogen
b. Oxygen d. Carbon
10. Iridium belongs to
a. First triad c. Fourth triad
b. Third triad d. Second triad
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |2

11. Employed as system acidifier


a. NaHCO3 c. CaCl3
b. NH3Cl d. B & C
12. Equal amounts of 2 isomers are called
a. Levorotatory c. Racemic mixture
b. Detrorotatory d. Optically active
 Racemic mixtrure- equal amount of 2 isomers. It will not rotate the plane of polarize light
because the rotator effect of the 2 isomers cancel each other.
13. Which of the following compounds is subject to addition reaction?
a. 1-propene c. 2-chloropropane
b. Benzene d. 1-propanol
 Addition reaction occurs in chemical compounds characterized by the presence of pi-bond
between 2 carbon or a carbon with another atom
14. It is used in the diagnosis of pancreatic tumor and growth
a. Selenomethionine Se-75 inj c. NaI
b. HIDA d. Tech 99m-Phytate
15. Flame test are observed under
a. Non-luminous flame c. A & B
b. Luminous flame d. None of these
16. The proton pump inhibitors are chemically known as
a. Ethenediamine c. Hydropropane
b. Propanimidamide d. Benzimidazole
17. Which of the following agents is clinically useful 5-HT1D receptor antagonist
a. Buspirone c. Sumatriptan
b. Losartan d. Propanolol
18. What is the form of insulin in the presence of zinc ion or at high concentration? This form of
insulin is the primary storage form in man
a. Monomer c. Pentamer
b. Dimer d. Hexamer
19. Which of the following drugs is an anion-exchanger
a. Colestipol c. Sitosterol
b. Nicotinic acid d. Probucol
20. Which of the following agents is classified as a tricyclic antidepressant
a. Trazodone c. Maprotiline
b. Amoxapine d. Amitryptiline
21. The chemical CH3OCH3 is an example of what type of organic compound
a. Ketone c. Ether
b. Ester d. Aldehyde
22. The structure given below is commonly called

a. Sec-pentyl c. Neo-pentyl
b. Tert-pentyl d. Isopentyl
23. An organic compound with a molecular formula C10H22 is most likely a/an
a. Alkane c. Alkyne
b. Alkene d. Cycloalkene
 Alkanes can be represented by the general formula CnH2n+2
 Alkene & cycloalkane CnH2n
 Alkyne CnH2n-2
24. Most abundant isotope
a. Deuterium c. Protium
b. Titrium d. Hydrogen
 Titrium (3neutrons) – unstable nucleus
 Deuterium & Hydrogen – stable and gives rise to deuterium oxides
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |3

25. It is used to detect & measure radioactivity


a. Geiger counter c. X-ray
b. Photographic plate d. All of the above
26. The place where reacting molecules may be absorbed are called
a. Reactive state c. Active site
b. Prosthetic site d. Adsorptive site
27. An alloy of antimony that contains 80% tin and 20% antimony
a. Babbit metal c. Anti-friction
b. Pewter d. None of the above
28. Grignard’s reagent usually contains
a. Co c. Fe
b. Cu d. Mg
29. Noble gases are all
a. Monoatomic c. Unreactive
b. Polyatomic d. A & C
 Characterized as completely filled s & p subshell. They are very unreactive
30. Solution that follows Raoult’s law
a. Standard solution c. Ideal solution
b. True solution d. B & C
31. “Greenish yellow” halogen
a. Fluorine c. Iodine
b. Chlorine d. Bromine
 This gaseous element takes its name from “chloros” meaning “greenish yellow”
32. It is found in H2O2 in concentration of 0.03% to increases its stability by catalytic retarding its
decomposition
a. Benzene c. Acetanilid
b. Ether d. None of the above
 Acetanilid in 0.03 % concentration increases the stability of H 2O2. In addition, compared with
other stabilizer it does not inactivate catalase
33. The only single acid that can dissolve gold
a. Hydrochloric acid c. Selenic acid
b. Nitric acid d. Aqua regia
 HCl and HNO3 can’t dissolve gold but when mixed as aqua regia in (3:1), it can dissolve gold
34. the first element discovered by means of spectroscope
a. Rubidium c. Technetium
b. Cesium d. None of these
35. An aluminum magnesium hydroxide sulfate
a. Maalox c. Magaldrate
b. Mylanta d. All of these
36. Purest native form of uncombined atom
a. Diamond c. Lamp black
b. Graphite d. Coal
 Diamond is considered the purest native form of uncombined carbon. It is one of the hardest
substance
37. It has become the drug of choice in the treatment of genital herpes
a. Amantadine c. Acyclovir
b. Idoxuridine d. Vidarabine
 Acyclovir has potent activity against several DNA viruses including herpes simplex type 1 and 2,
varicella-zoster and Epstein-Barr
38. The major constituent (98%) of the bones and teeth in which the cation is calcium
a. Hydroxyoxalate c. Hydroxyapatite
b. Raphides d. None of these
39. This metals exhibit autocomplexation
a. Noble metal c. Coinage metal
b. Volatile metals d. Alkaline earth metal
 Autocomplexation is manifested by the volatile metals. This group is composed of zinc,
cadmium, and mercury
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |4

40. D-(4-amino-4-carboxybutyl) is
a. Cephalosporin c. Chloramphenicol B
b. Synnematin d. Penicillin N
41. Cisplatin is
a. Platinol c. Used for cancer
b. A platinum complex d. All of the above
42. This gas was once named nitron
a. Radon c. Xenon
b. Argon d. Helium
 Radon is used in the treatment of cancer and was once called by Ramsay as nitron
43. Types of element nomenclature that gives the charge of the complex ion rather than the
oxidation state of the central unit.
a. Stock nomenclature c. Ewens-Bassett System
b. Classic nomenclature d. None of these
 Ewens-Bassett – utilize use of charge on the ion complex
 Classical – involves naming compounds using Latin or Greek prefix
 Stock – names compounds based on oxidation state of the central ion
44. It decolorizes KMnO4 and I2 solution
a. Peroxide c. Thiosulfate
b. Thiocyanate d. Dichromate
 Thiosulfate decolorizes iodine by forming tetrathionate ion & Manganate to Manganese ion
45. A statement that equal volume of gases at the same temperature & pressure is directly
proportional to the quantity of the gas
a. Avogardo’s number c. Avogadro’s law
b. Avogardo’s hypothesis d. Boyle’s law
46. Which of the following compounds is a 5-sulfamoylanthranilic acid derivative
a. Furosemide c. Triamterene
b. Cocaine d. Sulfadiazine
47. If entropy is zero the reaction is
a. C & D c. Spontaneous
b. Irreversible d. Reversible
48. Lanthanides has
a. 10 elements c. 15 elements
b. 5 elements d. 14 elements
49. Antidote for gold poisoning
a. Penicillamine c. EDTA
b. Activated charcoal d. Dimercaprol
50. An ion that often shows expectorant action
a. Iodide c. Fluoride
b. Phosphate d. Iodate
51. Represents a class of acidic inhibitors of prostaglandin synthetase, although it does not
antagonize PGE2 directly
a. Naproxen c. Piroxicam
b. Fenoprofen d. Zomepirac
52. This is emitted when a neutron converts to a proton
a. Positron c. Gamma ray
b. Negatron d. Alpha ray
 Positron – emitted when a nuclear proton changes to a neutron
53. Copper is an essential trace element used for the utilization of iron & occurs in
a. Hemoglobin c. Hemocyanin
b. Albumin d. Heme
 Hemoglobin – contains iron in its molecule
 Heme – constitutes about 4% of its weight consisting of iron in the center of the pyrrole-
porphyrin
 Albumin – Primary protein found in the blood
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |5

54. Borates in turmeric paper is colored


a. Olive c. White
b. Green d. Orange to red
 Turmeric paper when dipped into a solution of borate acidified with HCl & then drying the paper
will produce reddish brown color

55. A particle found in the nucleus of an atom is called


a. Nucleon c. Nuclide
b. Nuclei d. Proton
56. Precipitated sulfur is also known as
a. Sublimed sulfur c. Milk sulfur
b. Lac sulfur d. B & C
 Both lac sulfur & milk sulfur corresponds to precipitated sulfur
57. Which of the following cation is a member of the alkaline earth group
a. Li+ c. Ag+
b. Sr+2 d. Al+3

The Story of AlCroZan (Part 1: Cations Mnemonics)

 Group 1 Silver/Chloride Group


Alcrozan is a kargador of saba. One day he and his best bro carried heavy saba on their backs,
climbed the mountain and cried APH! Because it is too heavy.

 Group 2 Hydrogen Sulfide Group


“CuPbBiCd!”, they cried. (read as kupadbigat!) – Copper Subgroup

And they prayed that “SnHgAsSb” (Sana hagis saba para gumaan dala natin) – Tin Subgroup

 Group 3 Ammonium Sulfide Group


His buddy decided to confess that he has secret. He uttered with hesitancy, “AlCrZn” –
Aluminum Subgroup

FeMnNiCo! (read as feminine ako!) – Iron Subgroup

 Group 4 Ammonium Carbonate/Alkaline Earth Group


Alcrozan was shocked. However he accepts his best buddy. He said “BaCaMgSr” na ang
palengke sa bundok.

 Group 5 Alkali/Soluble Group


“LiKNaNH4” (read as Lika na, amoy -for ammonia- pawis ka na)
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |6

58. Which hormone possesses the following chemical structure?

A. Glucagon C. Insulin
B. Estrogen D. Thyroxine
59. Which of the ff is/are considered slow acetylators:
v. Eskimos
vi. Egyptians
vii. Filipinos
viii. Mediterranean Jews
a. III only d. II and IV only
b. I and II only e. I and III only
c. III and IV only
60. Calcium in a non-luminous flame emits a ________ color.
a. Brick red c. Golden yellow
b. Carmine red d. Yellowish green

Mr. Li: The Chinese Businessman Who Travels Around the World Using His Car

 LI rode a CAR
 Kia in VIOLET
 Eating SR CRIM
 From NAGOYa
 To BAYGing
 To COPPEMhaGen
 Thru a Car BRIdge

Hindi sinama ang Mg+2 and NH4+ sa kwento kasi mawawalan ng kulay ang kwento.
MAWAWALAN NG KULAY ang kwento.

61. Vleminckx’s solution is prepared by boiling sublimed sulphur and:


a. Lime c. calcium Carbonate
b. a & d d. Calcium oxide
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |7

62. Tienam is a combination of:


i. Piperacillin
ii. Cilastatin
iii. Tazobactam
iv. Imipenem
a. II and IV d. II and III
b. I and II e. I and III
c. I and IV
63. Give the IUPAC name of the given chemical CH2=CHCH2CH2CH3:
a. Pentene d. 1- pentyne
b. 1- pentene e. 2- pentene
c. Pentane
64. Which of the following is/are side effect/s of dactinomycin?

i. Alopecia
ii. Bone marrow depression
iii. Nausea and vomiting
a. I, II and III d. I only
b. I and II e. III only
c. II and III
65. Which of the following is/are factors affecting drug metabolism:

ix. Age
x. Economic status
xi. Species and strain
xii. Gender
a. I only d. I, III and IV only
b. AOTA e. I, II and III only
c. I and II only
66. The sum of the number of protons & neutron:
a. Mass number c. Isotope
b. Atomic weight d. Atomic number
67. Principle which states that it is impossible to accurately determine simultaneously the position
& motion of an electron:
a. Pauli’s exclusion principle c. Heisenberg principle
b. Aufbau principle d. NOTA
68. The 1st aminoglycoside antibiotic to be used in chemotherapy:
a. Amikacin d. Kanamycin
b. Gentamicin e. Neomycin
c. Streptomycin
69. Which of the following is/are brand name/s of Ibuprofen:
i. Tylenol
ii. Advil
iii. Siverol
a. I only d. AOTA
b. II only e. I and III
c. I and II only
70. The compound with the formula, CH3CH2COCH2CH3 is a/an:
a. Ketone d. Ether
b. Aldehyde e. Ester
c. Carboxylic acid
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |8

71. A preparation of 5% iodine in water with potassium iodide:


a. Iodine solution d. Mayer’s reagent
b. Iodine tincture e. Wagner’s reagent
c. Lugol’s solution
72. An ion that often shows expectorant action is:
a. Iodide c. Fluoride
b. Phosphate d. Iodate
73. The only single acid that can dissolve gold:
a. HCl c. Selenic acid
b. HNO3 d. Aqua regia
74. Argyria can be caused by:
a. Gold c. Iron
b. Cobalt d. Silver
75. BAL is:
a. British Anti- Lewisite c. 3,2 dimercaptopropranolol
b. 2,3 dimercaptopropranolol d. a and b
76. Elements of Group 6 have:
A. 6 C Atoms C. 6 valence electrons
B. 6 H atoms D. 60 oxygen atoms
77. The oldest antiseptic introduced by Dr. J. Lister
A. Phenol C. Iodine
B. Sulfonamide D. Ammonia
78. The most abundant metal and third most abundant element on the earth's crust
A. Sodium C. Carbon
B. Aluminum D. Copper
79. Symbolized as Pb
A. Plutonium C. Silver
B. Gold D. Lead
80. Amalgams are alloys of
A. Fe C. Hg
B. Zn D. Cu
81. Known as amphoteric substance
A. Salt C. Base
B. Acid D. Water
82. A system in which two opposing reactions are pccuring at the same time
A. Chemical equilibrium C. Chemical constant
B. Chemical reaction D. Hydrolysis
83. The following are inhalational anesthetics except;
A. Isoflurane C. Halothane
B. Nitrous oxide D. Phenobarbital
84. The following refers to a brand of Rimfampicin, except;
A. Ricin C. Rimactane
B. Rifadin D. Rifater
85. Physiologically inert substances added to active ingredient to provide convenience in swallowing
A. Stabilizers C. Lubricants
B. Surfactants D. Diluents
86. Synonym for Lactated Ringer's solution
A. Bronsted solution C. Saline solution
B. Hartmann's solution D. KISS
UST CA MODULE 1 ANSWER KEY – PHARMACEUTICAL CHEMISTRY 20% Page |9

87. Sr color in flame test


A. bluish green C. crimson red
B. emerald green D. carmine red
88. RCOR is a general formula for
A. ether C. aldehyde
B. ketone D. amide
89. Insulin which plays a vital role in regualting blood sugar contains this metal
A. Co C. Zn
B. Fe D. Mg
90. In analysis of cations, Group I are often called:
A. insoluble chloride C. soluble sulfide
B. insoluble sulfide D. soluble chloride
91. The following antimalarials are synthetic drugs, except;
A. Chloroquine C. Pamaquine
B. Quinacrine D. Quinine
92. Goiter may be caused by lack of:
A. Iodine C. Fluorine
B. Calcium D. Nitrogen
93. All ate iodine containing preparation, except;
A. Betadine C. Formol
B. Iodine tincture D. Lugol's solution
94. The most potent and most toxic local anesthetic
A. Proparacaine C. Metivacaine
B. Dibucaine D. Lidocaine
95. Spirit of Hartshorn is:
A. Strong ammonia solution C. HCl
B. Boric acid solution D. Aluminum hydroxide
96. Vitamin B12 is a naturally occuring chelate which contains
A. Fe C. Cu
B. Zn D. Co
97. Used as ingredient of eyewash solution
A. aluminum hydroxide C. sodium chloride
B. boric acid D. silver nitrate
98. A homogenous mixture of two or more substances
A. matter C. compound
B. solution D. element
99. Serious problem with abuse of CNS stimulants in the young
A. loss of sleep C. nutritional disturbances
B. induction of mental D. effect on the heart
abnormalities
100. Drugs that stimulates sympathetic division of the autonomic nervous system
A. stimulants C. adrenergic drugs
B. vasoprotective D. sedative
-END-

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