Genetic Predisposition

Precipitating Factors
- Age
- Diet and Lifestyle
- Sex
- Economic Status
- Heredity

Somatic Mutation in DNA

or Gene

Alteration of self-cells

Common Symptoms
- Excessive thirst
- Increased
urination Type 1 diabetes must be
- Unexplained treated with insulin. To do
weight loss Autoimmune response this, a person with type 1
- Headache
- Dehydration diabetes must inject insulin
- Irritability under their skin where it
- Mood swings can be absorbed into their
- Increased bloodstream to help glucose
appetite access the cells that require
- Fatigue it. Insulin can’t be taken in
Destruction of B Cells
- Disruption of pill form because the
menstrual cycles
digestive juices in the
and miscarriage
(in adults) stomach would destroy the
- Yeast infections insulin before it could work.
- Waking up in the
middle of the
night to urinate Insulin Deficiency

Type 1 DM