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Ⅳ.

Antihistamine Drugs
Rehistacal-B6 X
Each ml contains: 5ml/amp
Diphenhydramine HCl 4mg
Vitamin B6 1mg
Calcium bromide 40mg
醫令碼:IVEN6
Indication:
氣喘、過敏性鼻炎、蕁痲疹、皮膚炎、藥物過
敏症、皮膚搔癢症。
Dosage:
IV slowly 5ml qd-bid.
Contraindication:
孕婦禁用,早產兒及新生兒不建議使用。
Side effect:
輕度之睡意、熱感、倦怠、昏暈。
Cetirizine 2HCL B
Brand name:
Cety; Cetimin 10mg/tab
Cetirizine solution 60mg/60ml
醫令碼:OCEMI
醫令碼:OCETI
Indication:
Perennial and seasonal allergic rhinitis and other
allergic symptoms including urticaria.
Dosage:
Children≧6 yrs and Adults: 5-10mg QD or BID
2-5 yrs: 2.5mg/day MAX: 5mg/day QD or BID
12-23 months: initial 2.5mg QD may be increased
to 2.5mg BID
6-12 months : 2.5mg QD
Side effect:
Headache, drowsiness, somnolence, fatigue.
Precaution:
Dose > 10mg/day may cause significant
drowsiness.
Loratadine B
Brand name:
Finska 10mg/tab 醫令碼:OLOMI
Indication:
Relief of nasal and non-nasal symptoms of
seasonal allergic rhinitis.
Dosage:
Childre > 12 yrs and Adults: 10mg/day.
Children 2 yr-12 years- > 30 kg: 10mg/day.
≦30 kg: 5mg/day.
Side effect:
Headache, somnolence, fatigue, xerostomia,
palpitation.
Precaution:
1.Drink plenty of water.
2.May cause sedation, drowsiness and impair
coordination.
Desloratadine C
Brand name:
Denosin 5mg/tab 醫令碼:ODENOS
Indication:
Symptomatic relief of seasonal allergic rhinitis &
chronic idiopathic urticaria.
Dosage:
Adult & child >=12 yrs: PO 5mg once daily.
Side effect:
Nausea, headache, fatigue, pharyngitis, dry
mouth, somnolence
Precaution:
Patients with hepatic/renal impairment: PO 5mg
qod is recommended.
Clarinase
Contains:
Loratadine 5mg
Pseudoephedrone 120mg
sustaind release F.C. tab
Brand name:magnitude
Finska-LP; LoraPseudo-SR;
Minlife-P
醫令碼:OCLARI
Indication:
Relief of symptoms associated with allergic
rhinitis & common cold including nasal congestion,
sneezing, rhinorrhea, pruritus & lacrimation.
Dosage:
Adult and childn> 12yrs: 1 tad bid.
Side effect:
Insomnia, dry mouth.
Precaution:
Glaucoma, stenosing peptic ulcer, pyloroduodenal
obstruction, prostatic hypertrophy or bladder neck
obstruction.
Oral pseudoephedrine should be avoided during
the first trimester
Allerga C
Contains:
Fexofenadine 60mg/tab 醫令碼:OALLEG
Indication:
Relief of symptoms associated with allergic
rhinitis
Dosage:
Adult and childn> 12yrs: 1 tad bid.
Child:
Seasonal allergic rhinitis:
2 to 11 years, 30 mg ORALLY twice daily
with water.
12 years and older, 60 mg ORALLY twice
daily .
Side effect:
消化不良、肌痛、暈眩、嗜睡。
Precaution:
懷孕及授乳期間不應使用本品。
Chlorpheniramin B
Brand name:
CTM 4mg/tab 醫令碼:OCTM4
Indication:
Perennial and seasonal allergic rhinitis and other
allergic symptoms including urticaria.
Dosage:
Adult: 4mg q4-6hr up to 24mg/day.
Children (6-12 years): 2mg qid, not to exceed 12
mg/day; 2-6 years: 1mg q4-6hrs, not to exceed
6 mg in 24hrs.
Elderly: 4mg once or twice daily.
Contraindication:
Symptomatic prostate hypertrophy, during
asthmatic attack, narrow-angle glaucoma, bladder
neck obstruction.
Side effect:
Urinary retention, polyuria, diplopia, silght to
moderate drowsiness.
Precaution:
Anticholinergic action may cause significant
confusional symptoms.
Meclizine B
Brand name:
Bonamine ; Meclizine
25mg/tab
醫令碼:OBONA
Indication:
Prevention and treatment of symptoms of motion
sickness; management of vertigo with disease
affecting the vestibular system; labrinthine
disorders.
Dosage:
Motion sickness: 12.5-25mg 1 hrs before travel,
repeat dose q12-24hrs if need; doses up to 50mg
may be needed.
Vertigo: 25-100mg/day in divided doses.
Children (6-12y/o): 12.5-25mg 1 hrs before
travel.
Contraindication:
Pregnancy.
Side effect:
Drowsiness, sedation, blurred vision, dry mouth.
Precaution:
Don’t use in children < 3 years.
Brompheniramine C
Brand name:
Dimetane 4mg/tab 醫令碼:ODIM4
Indication:
Perennial and seasonal allergic rhinitis and other
allergic symptoms including urticaria.
Dosage:
Adults: 4-8mg tid or qid.
Children 6-12 years: 2-4mg tid or qid.
3-6 years: 2mg tid or qid.
< 3 years: 0.4-1mg/day.
Contraindication:
Narrow-angle glaucoma, bladder neck
obstruction, asthmatic attack.
Side effect:
Slight to moderate drowsiness, thickening of
bronchial secretion.
Precaution:
Use with caution in patients with heart disease,
hypertension, thyroid disease and asthma.
Peace C
Contains:
Pseu (Peace) syrup 60ml/bot:
Triprolidine 1.25mg/5ml
Pseudoephedrine 30mg/5ml
Peace tab:
Triprolidine 2.5mg/tab
Pseudoephedrine 60mg/tab
醫令碼:OPEAS
醫令碼:OPEAC
Indication:
鼻充血、過敏性鼻炎、打噴嚏等症狀。
Dosage:
Tab- Adult and 12 years :1 tab qid.
Children 6-12 years :1/2 tab tid-qid.
Syrup- Adult: 10 ml tid-qid.
Children 6-12 years: 5ml; 4-6 years: 3.75
ml, 2-4 years: 2.5ml; 4 months-2years
1.25ml; 3-4 times/day.
Contraindication:
禁用新生兒、授乳孕婦、下呼吸道疾患(Asthma)
及正使用MAOI 治療之患者。
Side effect:
CNS stimulation, sedation, mild drowsiness.
Precaution:
眼壓過高、前列腺肥大、高血壓、糖尿病、缺
氧性心臟疾患。
Cyproheptadine HCl B
Brand name:
Pilian 4mg/tab
Cypromin solution
0.4mg/ml,120ml/bot
醫令碼:OPERI
醫令碼:OCYPR
Indication:
Perennial and seasonal and other allergic symptoms
including urticaria, its off-labled uses have
induded appetite stimulation, blepharospasm,
cluster headaches, migraine spasm, schizophorenia,
and pruritus, and tradive dyskinesia.
Dosage:
Solution:
2-6 yrs: 5ml bid ~ tid.
7-14 yrs: 10ml bid ~ tid.
Allergy-
Adult: 4mg tid (MAX 32mg/day); 7-14 years:
4mg tid, Max of 16 mg.
Children 2-6 years: 2mg tid (MAX 12mg/day).
Stimulation of appetite-
Adults: 2-4mg tid or qid.
Children 2-6 years: MAX : 8mg.
Contraindication:
Narrow angle-glaucoma, stenosing peptic ulcer
avoid use in premature and term newborns due to
potential associated with SIDS (Sudden Infant
Death Syndrome).
Side effect:
Thickening of bronchial secretion, headache,
nervousness, abdominal pain, and arthralgia.
Precaution:
Safety and efficacy have not been established in
children < 2 years; cyprohepatadine has promoted
weight gain in anorexic adults; it’s easy to induce
CNS stimulating for children; syncope, toxic
confusion states, and hypotension in elderly.
Oxatomide
Brand name:
Tinset, Oxamide 30mg/tab 醫令碼:OTINS
Indication:
Common allergic disorder (eg. Hay fever, food
allergy, urticaria).
Dosage:
Adults- 30mg bid.
Children- 0.5mg/kg bid.
15-35 kg: 15mg bid.
≧ 35 kg: 30mg bid.
Side effect:
Rash, urticaria, angioedema, sommolence,
fatigue, nausea, vomiting.
Precaution:
1.Tinset is not suited for prompt relief of allergic
conditions such as asthma attacks.
2.Because of its hepatic elimination, Tinset should
be administered carfully to pt’s who have a
liver disorder.
Diphenhydramine HCl B
Brand name:
Diphenhydramine
(Re-Histamine) 30mg/ml/amp
醫令碼:IVENA
Indication:
過敏性疾患、蕁麻疹、皮膚炎、溼疹。
Dosage:SC, IM
Adults: 10-50mg q3h; critical diseae, MAX:
400mg/day.
Children: 5mg/kg/day, in 4 divided doses; MAX:
300mg/day.
Side effect:
睡意、胃腸障礙、食慾不振、喉鼻乾燥。
Precaution:
1.避免用CNS depressant agents 或飲酒
2.老人宜以最低有效起始劑量開始治療。
3.premature infants 及neonate 不建議使用。
4.以靜脈注射時,每次diphenhydramine 之劑量
以10mg-50 mg 為宜,且其注射速率不宜超過
25 mg/min。
5.有過敏症狀發生時應停用。
Dimenhydrinate B
Brand name:
Dramamine ; Doang 50mg/tab
Dimen 50mg/ml/amp
醫令碼:ODRAM
醫令碼:IDRAM
Indication:
Vomiting, vertigo and vomiting associated with
motion sickness.
Dosage:
IM, IV(> 2 min), Oral-
Adult: 50-100mg tid-qid; MAX 400mg/day.
IMChild:
1.25mg/kg qid, not to exceed 300mg/
day.
Oral-
Childn 2-5 yrs: 12.5-25mg bid-tid, MAX
dose: 75mg/day; 6-12 yrs: 25-50mg bid-tid,
MAX: 150mg/day.
For motion sickness: 50-100mg, 30 min before
travel.
Side effect:
Drowsiness, thickening of bronchial secretions,
weight gain, nervousness, rash.
Precaution:
BPH, peptic ulcer, narrow-angle glaucoma,
bronchial asthma, cardiac arrhythmias.
Azelastine HCL C
Brand name:
Azetin nasal spray
140mcg(0.14ml)/dose;20ml/bot
醫令碼:EAZET
Indication:
過敏性鼻炎.
Dosage:
Adult: 每次兩鼻孔各噴一下,每天使用兩次,
可依需要增加至每次噴兩下。.
5~11yrs: 每次兩鼻孔各噴一下,每天使用兩次
Side effect:
想睡、口乾、鼻腔乾燥、焦慮、憂鬱。
Precaution:
1.給藥後可能會產生苦味(因頭部過於向後傾
斜),偶爾有噁心感。
2.避免同時服用含酒精類溶液及其他中樞神經
抑制劑。
3. 使用本品後可能會有想睡或困倦的感覺,所
以操作機械要注意。

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