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Royal Medical College: 'Inspiring Health Skilled Students''
Royal Medical College: 'Inspiring Health Skilled Students''
CONTENTS
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ROYAL MEDICAL COLLEGE
‘’inspiring Health Skilled Students’’
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ROYAL MEDICAL COLLEGE
‘’inspiring Health Skilled Students’’
OBJECTIVES
The students are expected to achieve the following general educational objectives after
completion of the course:
Understand and use anatomical terms.
Understand the function of the various organs and their
Relations with one another.
Know the location of each organ and the important
Anatomical land marks.
Know the normal structure of the human body in general.
Use the knowledge of anatomy and physiology in pharmacology
Practice.
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CHAPTER ONE
Introduction
The word anatomy is derived from a Greek word “Anatome” meaning to cut up.
Anatomy: is the study of the structure and shape of the body and body parts & their
relationships to one another.
Physiology: is the scientific study of the normal function in living systems. Or you can
define simply, is the study of how the body and its parts work or function.
Body Planes
Midsagittal (median) plane: median plane –divides body into two equal halves.
Frontal (coronal) plane: divides body into anterior and posterior parts.
Sagittal Plane: divides body into right and left parts.
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Transverse (cross Section) plane: horizontal section divides into upper and
lower parts.
Directional Terms
o Superior: means the part is above another or closer to head (cranial)
o Inferior: means the part is below another or towards the feet (caudal).
o Anterior: means towards the front (the eyes are anterior to the brain) - [Ventral].
o Posterior: means toward the back (the pharynx is posterior to the oral (Cavity) -[dorsal].
o Medial: relates to the imaginary midline dividing the body into equal Right and
left halves (the nose is medial to the eyes).
o Lateral: means to words the side with respect to the imaginary midline (The ears
are lateral to the eyes).
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CHAPTER TWO
Integumentary system is an organ system consists of skin hairs, nails and sweat glands.
Integument means covering because skin covers the entire outside of the body, it
composed variety of tissues each of which has specific purpose.
The skin contains several types of epithelial tissue that are partially responsible for skins
protective function glands made of epithelial tissue provide secretions form body’s internal
environment to the external connective tissue attach skin to underlying muscle nerves tissue
is integrated though out the skin top help the body tract to the world around it.
Nerve is responsible for sensations of heat, cold pain, touch and pressure.
Skin
Skin is the thin layer of tissue forming the natural outer covering of the body of a person or
animal and divided into two or three layers.
Skin and commonly there are three types of the skin and they are:
1= Epidermis
x Sub layers
Cornfield layer
Granular Layer
Germinative layer
2= Dermis
Fair follicle
Sweat gland
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Sweat pores
Blood vessels
Nerves
3= Hypodermis
o Subcutaneous layer
Germination layer has cells called (Melanocytes) that produce melanin. Melanin protects color
change this layer has no blood vessels, not nutrient and oxygen obtains from (Dermis) by
process called diffusion.
Protection
Thermo regulation
Sensation
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Communication
Metabolism
Skeleton system
The frame works of the body consisting of bones and other connective tissue which protects
and support the body tissue and internal organs
The human skeleton contains 206 bones, six of which are tiny bone of the middle ear (3 in
each ear) that function in hearing.
The largest bone in the body is the thigh bone or femur. The human skeleton is the internal
frame work of the body. It composed of 270 bones at birth this total decrease to 206 bones by
adulthood after same bones have fused together the human skeleton can be divided into the axial
skeleton an appendicular skeleton.
Supportive
Support body
Provides framework of body
Gives shape to the body
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Protection
Movement
Storage
Provide calcium
Provide phosphorus
Classification of bones
1. Long bones
2. Short bones
3. Flat bones
4. Irregular bone
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Classification of bones
Axial 80 Bones
Skull: 22 Bones
Spine: 33 Bones
Ribcage: 25 Bones
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Bones of ribs 24
7+7= 14 of ribs is called true ribs because they are directly attached to the sternum.
3+3=6 of ribs is called false ribs because they indirectly connected to the sternum.
2+2=4 ribs is called floating ribs because they are not connects to the sternum but they are to
the abdominal muscles.
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1. 7 cervical vertebrate
2. 12 thoracic vertebrate
3. 5 Lumbar vertebrate
4. 5 sacrum vertebrate
5. 4 coccyx vertebrate
Bones is made up of living cells called osteocytes. Bones tissue made up of two types:
compact bone is hard and dense. Spongy bone is composed of small bony plates and it has
more space than compact bone. The hollow inner part of the bone is filled with soft substance
called marrow. Marrow comes into forms into the yellow and red.Yellow marrow is found in
central cavities is long bones and red bone is found the ends of long bones. Red bone marrow
is responsible for manufacturing RBCs. Yellow bone marrow is responsible for manufacturing
WBC and platelets. This manufacturing process is called Hematopoiesis.
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Joints
The point at which bones attach to each other called articulation, Joint make hundreds of motion
possible because the way bones are attached. Joints are classified according to the degree of
movement.
Fixed joints
Are immovable
joints. These joints
are not firmly fixed
infants but in
adulthood
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Semi-movable joint
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Movable joint
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Cell
All the basic building block thing or cell is the smallest structure and functional unit in body the
human body is composed of trillions of cell. Some of the basic functions of cell are: growth,
metabolism, irritability and reproduction. Human cells contain the following major part used
alphabetical order.
Cytoplasm
Within cell the cytoplasm is made up of a jelly like fluid called cytosine other structure
that surround the nucleus.
Cytoskeleton
The cytoskeleton is a network of long fibers that make up the cells structure frame work. The
cytoskeleton has several critical functions including demining cell shape participating in cells
division and allowing cells to move.
Endoplasmic reticulum
This organelle helps process molecules created by the cell the endoplasmic reticulum also
transport these molecules to their destination either inside or outside the cell.
Golgi apparatus
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Mitochondria
Mitochondria are complex organelle s that converts energy from food into a form that the
cell can use they have their own genetic material separate from DNAin the nucleus and can
make copies of themselves.
Nucleus
The nucleus serves as the cell command center sending direction to the cell grow mature
divide or die. it has also causes DNA ‘’ De-oxyribo nucleic acid’’ the cell heredity material
the nucleus is surround by membrane called nuclear envelope which protects and separated the
nucleus from the rest of cell.
Plasma membrane
The plasma membrane is outer living of the cell it separates the cell from its environment
and allows material to enter and leave the cells.
Ribosome’s
Ribosome’s are organelles that process the cell genetic in structurally create proteins these
organelles can float freely in the cytoplasm or be connected to the endoplasmic reticulum.
Tissue
Tissue is made up of many similar cells that perform a Specific function. And divided in to the
four types of human body tissue and their basic function.
o Connective tissue: anchors and support other body structure, blood is special types
of connective tissues that bring food and oxygen to the cell and carries wastes away
o Muscles tissue: Provides movement of the body
o Nerve tissue: conduct impulse to and from all parts of the body
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Epithelial Tissue
Connective Tissue
The different connective tissue is found human connective tissues are where connecting
the structure thereof, human body the main function of connective tissue is following:
Supportive
Connective other tissue
Provide all nutrients and remove waste product
Stores essential nutrient like fat and calcium
Muscle tissue
Muscle tissue contains fibers that contract and relaxation bring about movement chemicals sent
from muscles and nervous system.
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Functionally
o Smooth muscle
o Cardiac muscle
o Skeletal muscle
Appearance
Controls
Voluntary
Involuntary
Nervous system
Nerves tissue is compassed of neurons and neuralgia nervous are the actual working nerves cells
that response to stimuli there are several types of neurons but the two main types are the
sensory neuron and motor neuron, they send impulses to and receive impulses from all parts
of the body.
An organ is a group of different types of tissue that from in specific manner to perform a
definite function. Example the heart is organ is combination of muscle, nerves, connective
(Blood) and epithelial tissue. Organs do not work independently but are associated with other
organs. Organs have many functions. Group of organs are called systems, each organ
contributes its share to the function of the whole system do specialized work in the body, but all
systems depend on one another.
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CHAPTER FOUR
The cardio vascular system is designed for transportation and communication throughout all
parts of the body in approximately 1 minute a drop of blood travels through the right side of
the heart, lungs, left side of heart and systemic circulation completing its circuit by returning to
the right side of the heart. The cells located at the tips of toes and finger receive oxygen (O2)
from the lungs and nutrients from intestines. They send carbon dioxide (CO2) another wastes to
be excreted. The cardio vascular system plays vital role in it is process.
The cardio vascular system is composed of the heart and blood vessel it’s function include:
pumping blood and transporting gases, nutrient, and wastes.
1. Heart
The heart is a strong muscular pump organ it is weight 250-310g. It lays thoracic cavity behind
the sternum between the lungs. The heart is irregular shaped and slightly flat cone shaped.
The inferior point is apex which is formed by tip of the left ventricle; the apical pulse is counted
here. The superior is called base, lies and opposite the apex is formed moistly the left atrium.
Epicardium
Myocardium
Endo cardium
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A complete muscular wall called septum divides heart into two right and left sides.
The two sides are completely separated with no communication from right and left. Each side is
separate pump.
These are thin walled with low pressure receiving center for blood
Two lower chambers are right and left ventricles. These are high pressure
chambers because they pump blood out of the heart.
Left ventricle must contract with sufficient force to send blood entire of
the body therefore its muscle walls are thickest and its internal pressure is
highest.
The right ventricle needs only to pump blood into low pressure in lugs
therefore in thinner walled chambers.
Heart Valves
As each heart contract blood pushes into ventricle or out of the heart to the lungs or to the boy
the cardiac valve or opens and closes in response pressure changes either in the chambers cardiac
valve is unidirectional that allows blood following only one direction and preventing back flow.
Tricuspid valve
Pulmonary valve
Bicuspid valve ( mitral valve)
Aortic valve
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o Tricuspid valve
Regulates blood flow between the right atrium and right ventricle.
o Pulmonary valve
Controls blood flow from the right ventricle into the pulmonary arteries, which carry blood to
your lungs to pick up oxygen.
/HW¶VR[\JHQ-rich blood from your lungs pass from the left atrium into the left ventricle.
o Aortic valve
Opens the way for oxygen-rich blood to pass from the left ventricle into the aorta,
your body's largest artery, where it is delivered to the rest of your body.
Pumping action
Pumps blood to body and lungs
Receives blood from body and lungs
Influences blood pressure
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2. Blood
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o RBC
o WBC
o PLTS
Plasma 55%
o Albumin
o Globumin
o Fibrinogen active
o E.t.c
Function of blood
o Protection (defense)
o . Blood clot
o Protection (defense)
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WBC
They are a heterogeneous group of nucleated cells that are responsible for the body’s defenses
and are transported by the blood to the various tissues where they exert their physiologic role,
e.g. phagocytosis. WBCs are present in normal blood in smaller number than the red blood
cells (5.0-10.0 × 103/μl in adults). Their production is in the bone marrow and lymphoid
Tissues (lymph nodes, lymph nodules and spleen).
Neutrophil Granulocyte or polymorphonucleur Leukocyte
Esinophils
Basinophils
Lymphocytes A granulocyte or mononuclear Leukocyte
Monocytes
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Neutrophil Eosinophil
Basophil
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Blood Vessels
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CHAPTER FIVE
Respiratory system
The respiratory systemis responsible for drawing air intothe lungs. Exchanging oxygen for
carbon dioxide, and removing carbon dioxide in exchange for oxygen. The lungs depend on
the cardio vascular system to actively contribute to the process of gas exchange and to delivery
oxygen at the cellular level
Respiration: - Is the exchange of gases between a person’s external environment and the body’s
internal cells. Respiration refers to three processes: Ventilation (breathing), gas exchange (in
the alveoli of the lungs and in the cells of the body), and oxygen and carbon dioxide
transportation (for metabolism, body processes, and waste removal)
The nose and nasal cavity form the main external opening for the respiratory system and are the
first section of the body’s airway—the respiratory tract through which air moves. The nose is a
structure of the face made of cartilage, bone, muscle, and skin that supports and protects the
anterior portion of the nasal cavity. The nasal cavity is a hollow space within the nose
and skull that is lined with hairs and mucus membrane. The function of the nasal cavity is to
warm, moisturize, and filter air entering the body before it reaches the lungs. Hairs and mucus
lining the nasal cavity help to trap dust and other environmental contaminants before they can
reach the inner portions of the body..
Pharynx
Air travels from the nose to the pharynx, a tube shaped passage for air and food.
Nasopharynx.
The section of the pharynx that extends for the nares to the uvula is called thenasopharynx. It is
passageway for air only.
Oropharnx.
The oropharnx is part of the pharynx extending from the uvula to the epiglottis. Commonly
called the ‘’ Throat’’ the oropharnx carries food to the esophagus and air to the trachea.
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Laryngo pharynx
is lowest portion of the pharynx. It extends from the epiglottis to the openings of the larynx and
esophagus. The division of the laryngopharynx provides separate passageways for food and air.
From the pharynx, air passes into the larynx, a boxlike structure made of the cartilages held
together by ligaments. The function of these cartilages s keep the airway open at all times (the
largest and most prominent cartilage is the thyroid cartilage, commonly known as the ‘’ Adam’s
apple.’’ The larynx is located in the midline of the neck
Trachea (Windpipe)
Air passes from the larynx into the trachea, a tube approximately 4.5 inches (11cm) long and 1
inch in diameter in adults. It consists of cartilage and connective tissue and extends from the
lower end of the larynx into the chest cavity behind the heart. Immediately posterior to the
larynx and the trachea is the tube called esophagus, which transports food from the pharynx to
the stomach. The trachea’s horseshoe shaped cartilaginous rings provide sufficient rigidity to
keep it open at all the time for air to pass through the rings are flexible enough, however, to
permit bending of the neck.
Breathing
Ventilation (breathing) is the mechanical process of respiration that moves air to and from the
alveoli. Ventilation is divided into inhalation and exhalation. Breathing air in is called
inhalation or inspiration; breathing out is called exhalation or expiration. Adults usually
average between 12 and 20 respirations per minute’ the rate is much higher in children. Normal
respiration is calledeupnea; difficult breathing is known as dyspnea
Bronchi
As the bronchi enter the chest cavity, it divides into two smaller tubes called bronchi. There is
an indented area, called the hilum, where each bronchus enters the lung and branches off. The
arteries, veins bronchi, and nerves enter the lungs at the hilum as well. One (primary)
bronchus enters each lung. The right bronchus is shorter, straighter, and wider than the left
bronchus, which makes it a more common site for aspiration of foreign objects.
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Each bronchus continues to divide into smaller branches to from what commonly is called the
bronchial tree or tracheobranchial tree. This bronchial tree spreads throughout the lung tissue, as
the bronchi become smaller, their walls become thinner, the amount of cartilage decreases, and
they become known as the bronchioles. The bronchi and bronchioles continue to the lined with
ciliated mucous membrane. The bronchioles bran first into alveolar ducts
Protection
Speech Production
o Air passes over vocal cord to produce sound
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Common Terms
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REFERENCE
1. Human and anatomy physiology, by the William and Flora Hewlett Foundation.
2. LN_human_anat_Final PDF.
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