STRENGTH/ PREGNANCY

CLASS GENERIC BRAND DOSAGE FORM MOA INDICATION CONTRAINDICATION

CATEGORY

Anti-Diabetic Agents
1mg, 2mg, Promotes insulin release from Type-2 diabeties Diabetic
Sulfonaylurease Glimepride Getryl A
3mg, 4mg tab beta cells mellitus ketoacidosis
Type-2 diabeties
60mg, 120 mg Same as sulfonylurease, but has mellitus, Pregnancy, Breast
Glinides Nateglimide Glytan C
tab rapid and short duration of action Cardiopulmonary feeding
resustication

Increases glucose uptake and Type 1 and 2 DM,

Glucophage, 250mg, 500mg, Anemia, MI,
Biguanides Metformin consume it by targeted tissues. Hyperlipoproteiniemia B
Neodipar 650mg, 1g tab Respiratory distress
Without insulin fluctuations. , Obesity

Type 1 and 2 DM,

Cardiac failure,
softening and dilation
Thiazolidinones 15mg, 30mg, Reduce peripheral insulin Hepatic impairment,
Pioglitazone Dowglit of cervix before B
(Glitazone) 4mg tab resistance. Hypersensitivity
mechanical cervical
with drug insulin.
dilatation

Alpha Eclampsia,
50mg, 100 mg regulate intestinal carbohydrate
glycosidase Acarbose Acabose Type 1 and 2 DM, Ulcerative B
tab digestion and absorption
inhibitors conditions,
Dipeptidyl Inhibit DPP-4, works by
Hypersensitivity to
peptidase IV Vildagliptin Vildos 50 mg tab increasing amount of two Type 1 and 2 DM,
drug
inhibitors hormones, GLP-1 and GLP
INSULIN

Short acting 100 units/ml

Regular insulin Humulin R A
insulin SC injection
Rapid,
intermediate Aspart, protamine Novomix 100 units/ml A
acting Anlogue lowers blood glucose by
Hypersensivity,
70% isophane, stimulating peripheral glucose Type-1 and 2 DM
Premixed insulin Humulin 70/30 100 u/ml Hypoglycemia A
30% regular insulin uptake in skeletal muscles and fat.

Long acting Glargine Lantus solostar 100 u/ml A

Intermediate NPH insulin
Humulin N 100 u/ml A
acting (isophane)
 Anti-fungals
Broadest spectrum use
against number of Renally
Amphotericin yeasts and Endemic
Amphotericin B 50mg Inj compromised B
(lyophilized) Amphotericin B binds with the mycosis patients.
membrane lipid, ergosterol, and
increases fungal cell permeability
Anti-fungals Oropharyngeal thrush, Iv administration is
Nystatin Nilstat oral liquid vaginal candidiases toxic

Blocks fungal P450 enzyme to Conditions with low

Fluconazol Diflucan Tab 50mg, interfere ergosterol synthesis Fungal meningitis, white blood count B
150mg
Analgesic
Ibuprofen Brufen 200 mg tab Nasal polyp, C
Pain, fever,
Angioedema, CV
osteoarthritis
Paracetamol Calpol high risk patients B
500 mg tab
Rhematic associated Peptic ulceration, GI
topical gel 0.5
Non-selective Piroxicam P cam %
pain. disturbances
NSAIDs
Hypersensitivity to
Inhibit COX-1 and COX-2 diclofenac, renal
pathways insufficiency,
Diclofenac Esmert 50mg tab C
Rheumatoid arthiritis,
Osteoarthritis, mild to
moderate acute pain
Analgesic, antiplatelet GI disturbances,
effects Renally compromise
Salicylated Aspirin 75mg tab patients, B

Acute pain, Primary Ulceration,

Mefenamic acid Ponstan 250 mg tab Inhibit selective COX-2 pathway dysmenorrhea C

Antibiotics
Dental infections, Soft
375mg, 625mg, tissue and skin
Penicillin C0-Amoxiclave Augmentin A
1g tab infections, LRTIs,

Bacterial cell wall synthesis

inhibitor

Hypersensitive
 Bronchitis, UTIs,
Cefixime Cebosh 400mg tab Bacterial cell wall synthesis Cardiopulmonary A
inhibitor resustication,Pharyngit

s
rin
is, Pneumonia

po
os
Bone n joint Hypersensitive
al
ph infections, Dental
Ce
Cephalexin Keflex 500mg tab infections, Skin and A
soft tissue infections

Acute leukemia,
500 mg Inhibit cellwall synthesis, Blocks bactericimia, Brain
Glycopeptide Vancomycin Vinjec B
injectable glycopeptide polymerization abcessm colitic,
meningitis
Enterococcus
associated
endocarditis,Prosthetic Renal compromised
80 IM/IV,
Aminoglycoside Gentamicin Genticyn inhibit bacterial protein synthesis valve MRSA strains, patients, D
40 IM/IV Acute diarrhea, Hypersensitivity
Ulcerative colitis,

Inhibit protein synthesis by Acne vulgaris, Systemic lupus

Tetracycline Minocyclin Minogen 100mg tab D
binding 30s Clamydial infections, erythmatosus
Gonococcal infections
LRTIs, Skin and soft
Azithromycin Azomax 250mg tab tissue infections, Hypersensivity, A
Urethritis, CAP, Hepatic impaired
Inhibit protein synthesis by COVID (Offlabel) patients
Macrolides
binding 50s Chlamydial infections,
RTIs, Skin infections,
Clarithromycin Kelaricid 250mg tab Throat infections. Hypersensitivity A

A prodrug, active is Sulfapyrdine and Hypersensitvity,

5-Aminosalicylic acid (ASA), inhibit B and D if
Sulphonamide Sulfasalazine Azolfidine 500mg tab leukotriene synthesis and
Ulcerative colitis, RA, Urinary tract
prolong use
lipoxygenase. obstruction
 Bone and joint
250mg, 500mg
Ciprofloxacin Ciproxin infections, Acute B
tab
sinusitis,
Myasthenia gravis,
Flouroquinolone Inhibit DNA gyrase, promote
tendinitis, peripheral
s/Quinolone breakage of double strand DNA Acute sinusitis, CAP,
Moxcifloxacin Izilon 400mg infusion neuropathy B
Acute exacerbation

CAP, Nosocmial
Levofloxacin Leflox 500mg tab pnemonia, B
Complicated UTIs,

Vancomycin-resistant
Bind with 50s and prevent protein enterococcual infections,
Oxazolidinone Linezolid Nezkil 600mg infusion
translation.
Complicated skin Hypersensitvity A
infections, CAP, MRSA
infections

Anti-hypertensive
Angioedema,
2mg, 4mg, 8mg
Perindopril Coversyl tab
CHF, HF,HTN, MI Hypersensitivity, D
dry cough
Prodrug, competes with Salt depletion
Bening gastric ulcer
angiotensin-1 conversion into hypotension,
ACE inhibitors Ramipril Ramipace 5mg, 10mg, tab
angiotensin-2, and inhibit
associated with H.pylori, D
CHF, HT, Stroke stenosis
vasoconstriction
Acute HTN, CHF, Left Hypersensitivty,
Captopril Capoten 25 mg tab ventricular dysfunction anuria, D
with MI
Angioedema
150mg, 300mg HTN, Neuropathy in
Irbesartan Approval tab type-2 diabeties C,D

HTN, CHF, Renal

Candesartan 8 mg tab impairment C
Adrant Antagonizes the angitensin ll
ARB inhibitors Hypersensitivity
receptor
HTN, HTN with left
ventricular hypertrophy,
Losartan Tansin 50 mg tab Nephropathy in type-2 C
diabeties
 Acidosis, asthma, HF,
1mg/ml Cardiogenic shock,
Anti anginal, anti
Propanolol Inderal (injection), arrythmiatic, anti HTN Bronchospasm C
10mg, 40mg
Beta blockers Beta adrenergic antagonistof
Non-selective beta-1 and beta-2 receptors Asthma,
Cardiac arrythmia,
25mg, 6.25mg, cardiogenic shock,
carvedilol Carveda 12.5mg tab
Hypertension, A
cardiomyopathy hepatic
dysfunction

Angina, cardiac Cardiogenic shock,

metoprolol Betalok 20k 100mg tab arrythmias, HTN, MI A
bradycardia,
atrioventricular block
cardioselective, beta-1,
selective Sinus bradycardia,
Bisoprolol Concor 10mg tab antagonist HTN, HF cardiogenic shock, C
Hypersensititvity

25mg, 50mg Angina, Cardiac Asthma, depression,

Atenolol D
Tenormin tab arrythmias, HT HF
Angina, HTN, Cardiogenic shock,
Supraventricular Symtomatic
Verapamil Calan SR 240mg tab arrythmias, Tradive hypotension C
dyskinesia
inhibit transmembrane influx of sinoatrial node disease,
Ca-channel Angina pectoris, essential hypersensitvity, aortic
extracellular calcium ion across
blocker Amlopdipine Ampress 5mg, 10mg tab membranes HTN, Prophylaxis of stenosis B
angina

HTN, Cardiac Bradycardia, Sick

30mg, 60mg,
Diltiazem Herbressor 90mg tab
arrythmias, Coronary sinus syndrome C
artery spasm
Diuretics
Mannitol
Antagonizes the reabsorption of
17.5% w/v, Bladder irrigation,
Osmotic diuretic Mannitol Mannitol 20% water and sodium from kidney A
Sorbitol 2.5% cerebral edema acidosis, congestive
tubules
w/v heart failure
Inhibit H+ ion excreation, renal hyperchloremic
increasing Na, K, bicarbonate and acidosis, Addison's
Carbonic water excreation and produces Edema, epilepsy, fluid disease, liver disease
acetazolamide Diamox 250mg tab C
anhydrous alkaline duresis retention,
 Metolazone Metxone 5mg Inhibit reabsorption of Na in ventricular arrythmia C
Thiazide diuretic distal tubules with promote CHF, Edema, HF,
excreation of K and water Diabeties mellitus,
Hydrochlorthiazide Diuza 25mg B
hypercholestremia

edema, HTN, acute electrolyte

Loop diuretic furosemide Lasix 10mg/ml inj inhibit Na and Cl reabsorption at pulmonary edema C
imbalance
proximal and distal renal tubules
Amiloride
K+sparing 5mg, CHF, Duodenal Hyperkalemia, acute
amiloride Duride Inhibit Na reabsorption B
diuretic furesamide ulceration, HT renal failure, gout
40mg
Anti-Hyperlipedimic agents
HMG-CoA Atorvastatin Orva 10mg tab Hypersensitivity, D
selective HMG-CoA reductase Hypercholestremia,
reductase hyperlipidemia
inhibitor Rosuvastatin Rovista 5mg tab inhibitor Liver disease, renal D
impairment
Bind with bile acid, forms soluble Atherosclerosis, Bile
Bile acid 5g granules, 1g complex, increases fecal loss of bile salt-induced diarrhea, Intestinal
Colestipol acid-bound low density lipoprotein hypercholestremia C
sequestrants tab
cholestrol
obstruction

Hypersensitivity,
Lipoprotein Inhibit peripheral lipolysis, decrease
Gemfibrozil Gempid 600mg hepatic uptake of free faatty acids, Hypertriglyceridemiarenal disease, A
lipase activator
which inturn inhibit secretion of biliary cirrhosis
VLDL, may increase HDL-cholestrol
Sterol Inhibit sterol transporter at
absorption brush border and intestinal Hypercholestremia,
Ezetimibe Ezita 10mg Hypersensitvity C
inhibitor absorption of cholestrol Sitosterolemia