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Nano Technology in Biomedical
Nano Technology in Biomedical
Bridge Circuit
DC Bridges AC Bridges
DC Bridges
Wheatstone Bridge
AC bridges are used for measuring the values of inductors and capacitors or for
converting the signals measured from inductive or capacitive into a suitable form such
as a voltage.
The general ac bridge circuit consists of 4 impedances, an ac voltage source, and
detector.
The operation of the bridge depends on the fact that when certain specific circuit
conditions apply, the detector current becomes zero.
This is known as the null or balanced condition. Zero current means that there is no
voltage difference across detector.
The voltages at point a and b and from point a to c must be equal.
The condition for balance is given as
The important difference from the DC bridge balance equation is that, here not only the
magnitude of the impedances be balanced but also the phase angle.
Writing the impedances in their polar form, the above condition becomes,
General rule for AC bridges
Definition of Reactance, X
For a capacitor,
Deflection AC bridges
AC bridge can be used in two configurations: null and deflection modes.
In the null mode, the bridge is used to find the value of an L or C component
accurately.
In a deflection type bridge, the physical variable to be measured is converted to an
output voltage.
The deflection bridge is especially necessary in cases where the variable to be
measured is changing rapidly.
The results depend upon the value of the frequency as opposed to Maxwell bridge,
where the results were independent of the value of frequency.
2 2 2 2
ω C1 R1 = 1/Qc ≈ 0
Using this approximation, values of L3 and R3 can be found for high Q values.
L3 = C1R2R4
R3 =
Hay bridge is preferred for measuring inductances with high Q figures, while Maxwell’s
bridge works best with low Q inductors.
Schering Bridge
It is useful in measuring the capacitance and dielectric loss of a capacitor.
It is a device for comparing an imperfect capacitor in terms of a loss free standard
capacitor.
The imperfect capacitor is represented by its equivalent loss-free capacitor in series
with a resistance.
One arm contains a parallel combination of a resistor and a capacitor, and the
standard arm consists of only a capacitor.
The standard capacitor is usually a high quality mica capacitor.
A good quality mica capacitor has very low losses.
The junction between arms 3 and 4 is earthed.
Since capacitor impedances at lower frequencies are much higher than resistances,
most of the voltage will appear across capacitors.
Grounding of the junction affords safety to the operator from the high voltage hazards
while making balancing adjustments in arms 3 and 4.
The power factor of a series RC combination is defined as the cosine of the phase
angle of the circuit.
PF = Rx / Zx.
For phase angles close to 90˚, the reactance is almost equal to the impedance and
hence,
PF ≈ r/XC2 = ωC2r
The dissipation factor of a series RC circuit is defined as the cotangent of the phase
angle.
D = r/XC2 = ωC2r
We know that Q = XC/R.
This shows that dissipation factor is the reciprocal of the quality factor Q.
D = 1/Q
Substituting the values of C2 and r in D, we get,
D = ωR4C4.
Concepts of Filtering
To obtain a specific output from a device, it is sometimes necessary to
electronically sort through and pick out exactly what is desired from the
incoming signal.
Filters can simplify this process by altering the amplitude and phase of the signal
in a desired way.
In most applications, the signals we obtain contain more frequency components
than we want, so we use a filter to reject undesired components.
A filter is an electronic circuit that, by design attenuates sinusoidal voltage
signals at undesired components of a signal.
The changes made to a signal depend on the frequency contained in the signal
and the filter design. A filter is usually inserted between the input source and the
output.
where f = ω / 2π.
The low pass filter passes all frequency components lower than fc and rejects all frequency
components higher than fc. It is practically not possible to build a filter with sharp transition
from pass band to stop band, it takes some finite number of frequencies. Widely used filters
are low pass filter, high pass filter, band pass filter, band stop filter. All these filters have a pass
band, where they pass the frequency components and a stopband, where they reject or attenuate the
frequency components.
Preamplifiers
A preamplifier (preamp) is an electronic amplifier that prepares a small electrical
signal for further amplification or processing.
A preamplifier is often placed close to the sensor to reduce the effects of noise and
interference.
It is used to boost the signal strength to drive the cable to the main instrument without
significantly degrading the signal-to-noise ratio (SNR).
Preamplifiers may be:incorporated into the housing or chassis of the amplifier they
feed in a separate housing mounted within or near the signal source
Examples:
Similar to electrical transmission lines, an impedance matching problem exists when
transferring sound energy from one medium to another.
If the acoustic impedance of the two media are very different most sound energy will
be reflected (or absorbed), rather than transferred across the border.
The gel used in medical ultrasonography helps transfer acoustic energy from the
transducer to the body and back again.
Without the gel, the impedance mismatch in the transducer-to-air and the air-to-body
discontinuity reflects almost all the energy, leaving very little to go into the body.
The bones in the middle ear provide impedance matching between the eardrum
(which is acted upon by vibrations in air) and the fluid-filled inner ear.
Isolation Amplifier
They are commonly used for providing protection against leakage currents.
They break the ohmic continuity of electric signals between the input and output of
the amplifier.
The isolation includes different supply voltage sources and different grounds on each
side of the isolation barrier.
Three methods used in the design of isolation amplifiers are transformer isolation,
optical isolation, capacitive isolation.
The transformer approach uses either a frequency modulated or a pulse width
modulated carrier signal.
It uses an internal dc-to-dc converter comprising of a 20kHz oscillator, transformer,
rectifier and filter to supply isolated power.
Isolation by optical means is carried out by using a separate battery operated circuit
that supplies power to the patient circuit and the signal of interest is converted into
light by an LED.
It is a form of differential amplifier that allows measurement of small signals in the
presence of high common mode voltage by providing electrical isolation and
electrical safety.
Isolation amplifiers are used to allow measurement of small signals in the presence of
high common mode voltage. The capacity of an isolation amplifier is a function of 2
key isolation amplifier specifications.
1. The amplifier’s isolation breakdown voltage which defines the absolute
maximum common mode voltage that it will tolerate without damage.
Specifications of 1000 volts are common.
2. The amplifier’s common mode rejection ratio specification defines the degree
to which the common mode voltage will disrupt the normal mode component
measurement and therefore affect measurement accuracy.
The light falls on the phototransistor on the output side, which converts the light
signal again into an electrical signal.
The capacitive method of isolation uses digital encoding of the input voltage and
frequency modulation to send the signal across a differential capacitive barrier.
Separate power supply is needed on both the sides.
Merits
Transformer isolation amplifier is the most commonly used type.
Opto-coupled amplifier is cost effective followed by the transformer coupled
amplifier.
Opto coupled offers an isolation voltage of 800 V, transformer coupled offers 1200 V
and capacitance coupled offers 2200V.
Spectrum Analyzer
The spectrum analyzer, like an oscilloscope, is a basic tool used for observing signals.
The oscilloscope provides a window into the time domain, whereas the spectrum
analyzer provides a window into the frequency domain.
In the analyzer, a signal at the input first travels through the attenuator and the low
pass input filter.
The attenuator then limits the amplitude of the signal, while the filter eliminates the
undesirable frequencies.
Past the input filter, the signal gets mixed with another signal generated by a voltage
controlled oscillator.
The frequency of the VCO is controlled by a repeating ramp generator, whose voltage
also drives the horizontal axis of the display.
As the frequency of the VCO changes, the mixed input signal sweeps through the
resolution bandwidth filter which is fixed in frequency.
A detector then measures the power level of the signal passing through the IF filter,
producing a dc voltage that drives the vertical portion of the display.
As the VCO sweeps through its frequency range, a trace is drawn across the screen.
This trace shows the spectral content of the input signal within a selected range of
frequencies.
There are three essential steps in any spectrum analyzer measurement:
It is an oscilloscope that displays the data. It is actually a super heterodyne receiver in
which the local oscillator is a sweep generator. A low frequency wave is applied to both the
sweep oscillator and the horizontal deflection plates of the CRT producing a horizontal
deflection that is a function of frequency.
The lowest frequency of the sweep oscillator is represented by the left side of the trace, while the
highest frequency is represented by right side. The input signals are mixed with local oscillator
signal to produce signal. The bandwidth of amplifier is relatively narrow band, so the output
signal at the detector will have a strength that is proportional to the frequency.